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      Stem Cell Heterogeneity and Plasticity in Epithelia

      research Stem Cell Heterogeneity and Plasticity in Epithelia

      129 citations , May 2015 in “Cell Stem Cell”
      Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

      research Tracking Adult Stem Cells

      180 citations , January 2011 in “EMBO Reports”
      A combined approach is needed to fully understand adult stem cells, with genetic lineage-tracing being crucial.

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