December 2023 in “European Journal of Pharmacology” C3G and Vitisin A may help prevent hair loss by blocking male hormones and stopping hair cell death.
March 2026 in “Food Science and Biotechnology” The study investigates the effects of blue honeysuckle fruit aqueous extraction (BHAE) and its major component, cyanidin-3-O-glucoside (C3G), on hair growth. BHAE was shown to enhance the proliferation of human hair follicle dermal papilla cells and activate the β-catenin signaling pathway. In C57BL/6 mice, oral administration of BHAE accelerated the transition from the telogen to anagen phase, increasing hair follicle size and number. Molecular analysis revealed that β-catenin activation upregulated growth factors and cyclins. C3G replicated these effects, suggesting that BHAE, rich in C3G, promotes hair growth by activating β-catenin signaling, highlighting its potential as a functional food or cosmeceutical for hair regeneration.
5 citations
,
February 2025 in “International Journal of Molecular Sciences” Vitisin A reduces triglycerides better than Cyanidin-3-O-glucoside.
28 citations
,
March 2017 in “Endocrinology” Removing vitamin D and calcium receptors in mice skin cells slows down skin wound healing.
January 2025 in “Journal of the Korean Society of Food Science and Nutrition” Combining finasteride and black soybean extract better protects hair cells from damage and may treat hair loss effectively with fewer side effects.