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GlossaryCarcinomas

Carcinomas are a type of cancer that originates in epithelial cells, which line the surfaces of organs and structures throughout the body. While not directly related to hair loss, certain carcinomas, particularly those affecting the scalp or skin, can lead to hair loss due to localized treatments like radiation or surgical removal. Additionally, some systemic treatments for cancer, such as chemotherapy, can cause widespread hair thinning or loss as a side effect. Understanding carcinomas is important in the context of hair biology, as they can impact the health of hair follicles and the scalp environment.

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The Hair Cycle of the Mouse and Its Importance in the Study of Sequences of Experimental Carcinogenesis

research THE HAIR CYCLE OF THE MOUSE AND ITS IMPORTANCE IN THE STUDY OF SEQUENCES OF EXPERIMENTAL CARCINOGENESIS

111 citations , March 1951 in “Annals of the New York Academy of Sciences”

Understanding the mouse hair cycle is crucial for cancer research.

research Transgenic mice overexpressing protein kinase C epsilon in their epidermis exhibit reduced papilloma burden but enhanced carcinoma formation after tumor promotion.

99 citations , February 2000 in “PubMed”

Overexpressing PKCepsilon in mice reduces papillomas but increases carcinomas.

research Inducible Cutaneous Inflammation Reveals a Protumorigenic Role for Keratinocyte CXCR2 in Skin Carcinogenesis

70 citations , December 2008 in “Cancer Research”

CXCR2 in skin cells promotes tumor growth.

WNT10A Promotes an Invasive and Self-Renewing Phenotype in Esophageal Squamous Cell Carcinoma

research WNT10A promotes an invasive and self-renewing phenotype in esophageal squamous cell carcinoma

55 citations , March 2015 in “Carcinogenesis”

WNT10A helps esophageal cancer cells spread and keep renewing themselves.

research Targeted expression of spermidine/spermine N1-acetyltransferase increases susceptibility to chemically induced skin carcinogenesis

54 citations , February 2002 in “Carcinogenesis”

Increasing SSAT makes skin more prone to cancer.

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