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GlossaryCardiac Hypertrophy

thickening of heart muscle due to increased workload

Cardiac Hypertrophy, also known as Myocardial Hypertrophy, is the thickening of the heart muscle, specifically the myocardium. This condition can result from increased workload on the heart due to high blood pressure or other cardiovascular diseases, leading to an enlarged heart that may struggle to pump blood efficiently. While it can be a compensatory response to increased demand, prolonged hypertrophy can lead to heart failure and other complications.

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Research

5 / 1000+ results

research Antiandrogenic Therapy With Finasteride Attenuates Cardiac Hypertrophy and Left Ventricular Dysfunction

56 citations , January 2015 in “Circulation”

Finasteride helps reduce heart issues and improves heart function.

research Maternal androgen excess induces cardiac hypertrophy and left ventricular dysfunction in female mice offspring

21 citations , July 2019 in “Cardiovascular Research”

High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.

Maternal Androgen Excess Inhibits Fetal Cardiomyocyte Proliferation Through RB-Mediated Cell Cycle Arrest and Induces Cardiac Hypertrophy in Adulthood

research Maternal androgen excess inhibits fetal cardiomyocytes proliferation through RB-mediated cell cycle arrest and induces cardiac hypertrophy in adulthood

2 citations , August 2023 in “Journal of Endocrinological Investigation”

Excess maternal androgens can cause heart problems in offspring.

research Targeting cardiac hypertrophy through a nuclear co‐repressor

3 citations , October 2019 in “EMBO molecular medicine”

Targeting NCoR1 can help treat heart enlargement and dysfunction.

research Gender Differences in Cardiac Hypertrophy

27 citations , February 2020 in “Journal of Cardiovascular Translational Research”

Women generally handle heart enlargement better than men, but it's riskier for them if it occurs; hormones like estrogen offer some protection.

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Community Join

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community The Biggest Concern That I Have For Oral Minoxidil: Cardiac Hypertrophy

in Minoxidil 27 upvotes 3 years ago

Oral minoxidil can cause serious heart issues like cardiac hypertrophy and arrhythmias, prompting some users to reduce dosage or switch to topical treatments. Despite significant hair regrowth, side effects such as shortness of breath and chest pains are common concerns.

community Extreme caution: my experience using Ru58841 only once

in Treatment 10 upvotes 1 year ago

An 18-year-old experienced severe side effects, including heart palpitations and high blood pressure, after using RU58841 once, leading to a referral to cardiology for suspected left ventricular hypertrophy. The user regrets using RU58841 and seeks advice on recovery, while others suggest preexisting conditions or genetic predispositions may be factors.

community Don't fall for the fear mongering bros

in Satire 1530 upvotes 1 year ago

Hair loss treatments discussed include finasteride, minoxidil, spironolactone, and estradiol, with concerns about side effects like sexual dysfunction and feminization. Some users prefer hair transplants or shaving over medication due to potential side effects.

community Male pattern baldness is not cosmetic.

in Chat 222 upvotes 8 months ago

Male pattern baldness is linked to health risks and should be treated medically. Finasteride is effective and should be insurance-covered.

community Oral Minoxidil Study of 60 AGA patients

in Minoxidil 70 upvotes 4 years ago

Oral minoxidil treatment increased hair density and shaft caliber in AGA patients. Side effects included hypertrichosis and lower extremity edema, with younger patients experiencing fewer side effects.

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