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Efficient Genome Editing Using CRISPR/Cas9 Ribonucleoprotein Approach in iPS Cells for Recessive Dystrophic Epidermolysis Bullosa

research 924 Efficient genome editing using CRISPR/Cas9 ribonucleoprotein approach in iPS cells for recessive dystrophic epidermolysis bullosa

April 2019 in “Journal of Investigative Dermatology”

Researchers fixed gene mutations causing a skin disease in stem cells, which then improved skin grafts in mice.

research Non-viral delivery of the CRISPR/Cas system: DNAversusRNAversusRNP

21 citations , January 2022 in “Biomaterials Science”

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

research Strategies for High-Efficiency Mutation Using the CRISPR/Cas System

29 citations , February 2022 in “Frontiers in Cell and Developmental Biology”

Improving CRISPR/Cas systems can make gene editing more efficient and precise.

research Ultrasound-activated particles as CRISPR/Cas9 delivery system for androgenic alopecia therapy

47 citations , December 2019 in “Biomaterials”

Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.

research Pre-clinical non-viral vectors exploited forin vivoCRISPR/Cas9 gene editing: an overview

23 citations , January 2022 in “Biomaterials Science”

Non-viral vectors show promise for safe and effective CRISPR/Cas9 gene editing in treating diseases.

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community The pessimism about the Crisp Cas 9 is excessive

in Chat 11 upvotes 10 months ago

CRISPR Cas9 could potentially treat baldness by targeting specific genes in hair follicles without affecting other body functions. There is optimism about its future use, despite ethical concerns and the current reliance on treatments like minoxidil and finasteride.

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