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Research
5 / 1000+ resultsresearch The value of Trichoscopy and Histopathology in the diagnosis of post-COVID-19 telogen effluvium
This study investigates the distinct trichoscopic and histopathological features of post-COVID-19 telogen effluvium (TE) in 13 patients. Trichoscopy revealed thick, livedoid arborizing vessels and giant serpiginous vessels in 38% of cases, with a strong correlation between the presence of giant vessels and the need for supplementary oxygen during COVID-19 infection (p=0.001). Histopathology showed a catagen/telogen shift and a consistent superficial perivascular and perifollicular lymphocytic infiltrate, suggesting a direct viral or immune-mediated insult. These findings highlight the unique vascular patterns that can help distinguish post-COVID-19 TE from classical TE.
research `Cyclic alopecia' inMsx2mutants: defects in hair cycling and hair shaft differentiation
Msx2-deficient mice experience irregular hair growth and loss due to disrupted hair cycle phases.
research In Vivo Non-Invasive Observation of Dynamic Changes in Hair Shaft, Melanin, and Collagen During the C57BL/6 Follicle Cycle
Non-invasive methods can effectively monitor hair growth cycles, aiding hair loss treatment development.
research A comparative study of histopathologic features in alopecia areata and pattern hair loss
The study found certain scalp biopsy features can help tell apart alopecia areata from pattern hair loss even when typical immune cells are not seen.
research Healthy Hair: Form and Function
Hair health is influenced by genetics, aging, and environmental factors, with proper care needed to maintain it.
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5 / 72 resultscommunity Hair loss over a year following depression and taking antidepressants
A 33-year-old experienced significant hair loss after a depressive episode and taking paroxetine, possibly due to telogen effluvium or androgenic alopecia. Suggestions included reducing alcohol, considering finasteride and minoxidil, and consulting a doctor about antidepressant side effects.
community HLT Megathread on HMI-115 (key takeaways in comments)
HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.
community A lot of hair falling out like this, what does it mean? Diffuse thinning, chronic dandruff and scalp crust (seborrheic dermatitis), 28 y/o male
A 28 year old male experiencing diffuse thinning, chronic dandruff and scalp crust (seborrheic dermatitis), with replies discussing the use of topical fin for hormone imbalances and Nizoral for seb derm.
community 1 year of finasteride 1.25 mg daily. 21->22 years old.
The conclusion of the conversation is that the user experienced significant hair regrowth after taking finasteride for a year. They did not use any other treatments and did not experience any noticeable side effects.
community PP405 Won’t Work: Follicle Is Miniaturized, Fibrosed, And Missing Key Support Cells
PP405 is ineffective for miniaturized, fibrosed hair follicles in androgenetic alopecia. AMP303 may activate hair follicle stem cells, but minoxidil and finasteride are still the main treatments.