research 054 Deep Analysis of CD4+ Trm Cells in Normal and Atopic Dermatitis Human Skin November 2025 in “Journal of Investigative Dermatology” Certain immune cells in atopic dermatitis skin could be targeted for treatment.
research Skin CD4+ memory T cells exhibit combined cluster-mediated retention and equilibration with the circulation 155 citations , May 2016 in “Nature communications” Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.
research Skin-infiltrating CD4+ lymphoma cells depend on hair follicle-derived IL-7 September 2016 in “Journal of Dermatological Science” Hair follicles produce IL-7, which is essential for certain skin lymphoma cells to survive.
research Local heroes or villains: tissue-resident memory T cells in human health and disease 67 citations , January 2020 in “Cellular & Molecular Immunology/Cellular & molecular immunology” Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.
research Hair follicle–derived IL-7 and IL-15 mediate skin-resident memory T cell homeostasis and lymphoma 245 citations , October 2015 in “Nature medicine” Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.