research Retracted: Causal Role of Immune Cells in Alopecia Areata: A Two-Sample Mendelian Randomization Study
The study suggested certain immune cells might cause alopecia areata, but it was retracted.
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5 / 62 resultsresearch Induction of T Cell Exhaustion by JAK1/3 Inhibition in the Treatment of Alopecia Areata
Ifidancitinib, a JAK inhibitor, effectively regrows hair in mice with alopecia by tiring out harmful T cells.
research CXCR3 Blockade Inhibits T Cell Migration Into the Skin and Prevents Development of Alopecia Areata
Blocking the CXCR3 receptor reduces T cell accumulation in the skin and prevents hair loss in mice.
research Characterization of Pathogenic CD8+ T Cells in an Adoptive Transfer Mouse Model of Alopecia Areata in C3H/HeJ Mice
Certain CD8+ T cells attack hair follicles in alopecia areata, suggesting they could be targeted for treatment.
research Comparative Spatial Transcriptomics of Hair Follicle-T Cell Interactions in Mouse, Dog, and Human Reveals Conserved Drivers of Primary Cicatricial Alopecia
Potential therapeutic targets for scarring hair loss are identified.
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