research Th1 effector CD4 T cells rely on IFN-γ production to induce alopecia areata May 2025 CD4 T cells need IFN-γ to cause hair loss in alopecia areata.
research Alopecia areata: Animal models illuminate autoimmune pathogenesis and novel immunotherapeutic strategies 82 citations , March 2016 in “Autoimmunity reviews” Animal models have helped understand hair loss from alopecia areata and find new treatments.
research Alopecia areata: a review of disease pathogenesis 191 citations , May 2018 in “British journal of dermatology/British journal of dermatology, Supplement” Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.
research IL-15 in T-Cell Responses and Immunopathogenesis 48 citations , January 2024 in “Immune Network” IL-15 is key for T cell function and could help improve treatments for immune-related diseases.
research Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition 701 citations , August 2014 in “Nature medicine” Alopecia areata can be reversed by JAK inhibitors, promoting hair regrowth.