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research Transduction‐induced overexpression of Merkel cell T antigens in human hair follicles induces formation of pathological cell clusters with Merkel cell carcinoma‐like phenotype

5 citations , August 2021 in “Experimental dermatology”

Overexpressing Merkel cell virus proteins in human hair follicles can create clusters of cells that resemble Merkel cell cancer.

research 1378 Identification of two distinct stem cell clusters, Lrig1-derived and Wnt/CD44-dependent, in corneal epithelium

April 2018 in “Journal of Investigative Dermatology”

The conclusion is that the cornea has two types of stem cells, with Lrig1+ cells being key for renewal in aging corneas, independent of CD44.

research Exploring machine learning strategies for single-cell transcriptomic analysis in wound healing

5 citations , January 2025 in “Burns & Trauma”

Machine learning and single-cell analysis improve understanding and treatment of wound healing.

research 644 Tumor cell adhesion as a risk factor for SLN metastasis and predictor of disease recurrence in primary cutaneous melanoma

April 2016 in “Journal of Investigative Dermatology”

Tumor cell adhesion is linked to higher risk of SLN metastasis and melanoma recurrence, and a model including these factors predicts these outcomes better than one with just clinical data.

research Responses of hair follicle–associated structures to loss of planar cell polarity signaling

29 citations , February 2013 in “Proceedings of the National Academy of Sciences of the United States of America”

Loss of Fz6 disrupts hair follicle and associated structures' orientation.

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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community Researchers working on ways to regenerate lost hair from stem cells identified a recipe for normal hair regeneration in the lab. “A method for cyclical regeneration of hair follicles from hair follicle stem cells and will help make hair follicle regeneration therapy a reality in the near future.”

in Research/Science 258 upvotes 5 years ago

Hair loss treatments like finasteride, minoxidil, and hair transplants have side effects and limitations. There is hope for future advancements in stem cell therapy and hair follicle regeneration, though skepticism about their effectiveness and timeline persists.

community Is DHT actually the cause of male pattern hair loss or just a correlating factor? Why I think the research is more complicated than we're told and why I've been looking into GHK-Cu

in Research/Science 74 upvotes 3 months ago

DHT is not the only cause of male pattern hair loss; genetic sensitivity, inflammation, and fibrosis also contribute. GHK-Cu, a copper peptide, is being explored as an alternative treatment to finasteride and minoxidil, showing potential in improving follicle health.

community Accelerated Hair Loss from Creatine

in Finasteride/Dutasteride 134 upvotes 9 months ago

Creatine may cause hair loss in some individuals, especially those on finasteride, despite no scientific link. Personal experiences suggest individual sensitivity to DHT could be a factor.

community Summary of Procapil video by Haircafe

in Minoxidil 2 upvotes 1 year ago

Procapil is marketed as a natural hair loss treatment but lacks strong evidence and is industry-biased. Minoxidil and Finasteride are the only FDA-approved treatments for androgenetic alopecia.

community An argument for why we should take topical Dutasteride seriously

in Research/Science 85 upvotes 5 years ago

Topical Dutasteride may halt hair loss and effectively treat androgenic alopecia. Combining low-dose oral Dutasteride with topical application could maximize regrowth and minimize side effects.

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