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GlossaryStem Cell Function

ability to self-renew and become specialized cell types

Stem cell function refers to the ability of stem cells to self-renew and differentiate into various specialized cell types. This means they can both replicate themselves to maintain the stem cell pool and transform into different types of cells needed for growth, repair, and maintenance of tissues, including hair follicles. This dual capability is crucial for regenerative medicine and understanding conditions like alopecia, where hair growth is disrupted.

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Research

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research Spermidine Promotes Human Hair Growth and Is a Novel Modulator of Human Epithelial Stem Cell Functions

61 citations , July 2011 in “PLOS ONE”

Spermidine may help reduce hair loss and deserves further testing as a treatment.

research Patched1 Functions as a Gatekeeper by Promoting Cell Cycle Progression

176 citations , February 2006 in “Cancer Research”

Patched1 helps prevent tumors by controlling cell growth.

research Vestibular Hair Cell Regeneration and Restoration of Balance Function Induced by Math1 Gene Transfer

129 citations , January 2007 in “Otology & Neurotology”

Gene therapy with the Math1 gene helped regenerate balance-related cells and improve balance in mice.

research The structural and functional aspects of hair cell regeneration in the chick as a result of exposure to intense sound

63 citations , January 1992 in “Experimental Neurology”

Chickens exposed to loud noise can quickly regain hearing mostly due to repair of the tectorial membrane, not just hair cell regeneration.

Essential Role of Polarity Protein Par3 for Epidermal Homeostasis Through Regulation of Barrier Function, Keratinocyte Differentiation, and Stem Cell Maintenance

research Essential Role of Polarity Protein Par3 for Epidermal Homeostasis through Regulation of Barrier Function, Keratinocyte Differentiation, and Stem Cell Maintenance

26 citations , July 2016 in “The journal of investigative dermatology/Journal of investigative dermatology”

The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.

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Community Join

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community Fully Functional Hair Follicles Have Been Grown in The Lab For The First Time

in Research/Science 383 upvotes 5 months ago

Scientists have successfully grown functional hair follicles in the lab, marking a significant advancement in hair regeneration research. A user shared their personal experience with hair loss treatments, including Minoxidil and Finasteride, and plans to share a detailed protocol for hair restoration.

community What do you guys think of stem cell hai restoration?

in Chat 11 upvotes 7 months ago

Stem cell hair restoration lacks scientific evidence and is often considered a scam. Effective hair loss treatments include hair transplants, Minoxidil, and Finasteride, but stem cell treatments are not proven.

community Functional hair follicles grown from stem cells: Scientists have created natural-looking hair that grows through the skin using human induced pluripotent stem cells (iPSCs), a major scientific achievement that could revolutionize the hair growth industry.

170 upvotes 7 years ago

Scientists have grown natural-looking hair from stem cells, potentially revolutionizing hair growth treatments. Concerns include cost, DHT resistance, and the need for future procedures.

community Japan-led "Third Cell" Discovery: Is this the missing link for full follicle regeneration?

in Technology 132 upvotes 5 months ago

A new "third cell" discovery in Japan could be key to fully regenerating hair follicles, with human trials possibly starting in 2027-2028. AI is expected to accelerate medical discoveries, potentially leading to a hair loss cure within a few years.

community Why did this recent research paper from professor Tsuji lab in Japan largely go unnoticed by this sub? Isn't this discovery huge? (hair cloning)

in Research/Science 31 upvotes 2 months ago

A recent discovery in hair cloning identified a previously unknown cell type essential for hair follicle growth, which could potentially make lab-grown hair viable if translated to humans. However, skepticism remains due to past delays and the challenges of replicating results in humans and making the process affordable.

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Learn

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learn Stem Cell Factor

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Ketoconazole

antifungal with some anti-androgenic benefits, often used as a shampoo

learn Thymosin Beta 4

learn Epidermal Growth Factor

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