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research Omega-6 highly unsaturated fatty acids in Leydig cells facilitate male sex hormone production

7 citations , September 2022 in “Communications biology”

Omega-6 fats in certain cells boost male hormone production.

research Free internal lipids in hair from pre‐ and post‐menopausal women

7 citations , March 2005 in “International Journal of Cosmetic Science”

Menopause reduces hair quality, but hormone therapy can help improve it.

research RETRACTED: Serum lipids may causally affect the occurrence of alopecia areata: A Mendelian randomization study

3 citations , June 2024 in “Skin Research and Technology”

Higher LDL lipids may increase alopecia areata risk, while higher triglycerides may decrease it.

research Sdr16c5 and Sdr16c6 control a dormant pathway at a bifurcation point between meibogenesis and sebogenesis

June 2023 in “Journal of biological chemistry/The Journal of biological chemistry”

Sdr16c5 and Sdr16c6 genes regulate a key point in lipid production that affects eye and skin gland function.

research Runx1 Role in Epithelial and Cancer Cell Proliferation Implicates Lipid Metabolism and Scd1 and Soat1 Activity

24 citations , July 2018 in “Stem cells”

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

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community Running Gear- Preemptive Treatment

in Product 9 months ago

A 51-year-old on TRT plans to use steroids and is concerned about hair loss, considering topical treatments like Hair Rescue with RU58841 and finasteride, along with Nioxin shampoo. They are cautious about using oral DHT blockers due to potential interactions with steroids like Tren and Anavar.

community Bile Acid-Mediated DHT Dysregulation Hypothesis

in Research/Science 13 upvotes 1 year ago

Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 2 years ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Dht kills hair, but no one says why?

in Finasteride/Dutasteride 40 upvotes 11 months ago

DHT affects hair follicles, contributing to hair loss, but the exact mechanism is unclear. Treatments like finasteride and minoxidil are used to manage hair loss, though they may have side effects and varying effectiveness.