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Integrated Single-Cell Chromatin and Transcriptomic Analyses of Human Scalp Reveal Etiological Insights Into Genetic Risk for Hair and Skin Disease

research Integrated Single-Cell Chromatin and Transcriptomic Analyses of Human Scalp Reveal Etiological Insights Into Genetic Risk for Hair and Skin Disease

September 2022 in “bioRxiv (Cold Spring Harbor Laboratory)”

The research provided new insights into the genetic factors contributing to hair loss and skin conditions by analyzing individual cells from the human scalp.

research Single Cell Analysis of Transcriptome and Open Chromatin Reveals the Dynamics of Hair Follicle Stem Cell Aging

3 citations , July 2023 in “Frontiers in Aging”

Hair follicle stem cells change states with age, affecting hair growth and aging.

research How a Bird Gets Its Feathers: Insights from Chromatin Looping

3 citations , June 2020 in “Developmental Cell”

Feather patterns are influenced by enhancers and chromatin looping, and the structure of protein complexes important for hair growth has been detailed.

research Single-Cell Chromatin Landscapes of Mouse Skin Development

2 citations , December 2022 in “Scientific Data”

The study maps how genes are regulated during mouse hair growth.

research ATP-Dependent Chromatin Remodeling During Mammalian Development

182 citations , August 2016 in “Development”

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

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community TWIST-1 and the cure: Is it really that easy?

in Research/Science 283 upvotes 3 years ago

TWIST-1 gene's role in hair loss and potential as a treatment target. Inhibiting TWIST-1 may prolong hair growth and reduce hair follicle sensitivity to DHT.