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GlossaryChronic Mucocutaneous Candidiasis

persistent fungal infections of skin, nails, and mucous membranes

Chronic Mucocutaneous Candidiasis (CMC) is a condition characterized by persistent and recurrent infections of the skin, nails, and mucous membranes (such as the mouth and genitals) caused by the Candida species of fungi. This condition often results from an underlying immune system defect, making it difficult for the body to control Candida growth.

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Research

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research The L412F variant of Toll-like receptor 3 (TLR3) is associated with cutaneous candidiasis, increased susceptibility to cytomegalovirus, and autoimmunity

55 citations , November 2010 in “Journal of Allergy and Clinical Immunology”

The L412F variant of TLR3 is linked to skin infections, more viral infections, and autoimmune issues.

research Alopecia areata in a Patient with Candidiasis-Endocrinopathy Syndrome: Unsuccessful Treatment Trial with Diphenylcyclopropenone

16 citations , January 1995 in “Dermatology”

The treatment for alopecia areata with diphenylcyclopropenone was unsuccessful.

research Cutaneous Manifestations in Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy (APECED): A Comprehensive Review

January 2024 in “Biomedicines”

The review shows that skin symptoms like chronic fungal infections, hair loss, and skin depigmentation are key for early detection and management of APECED.