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Research

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research Effect of Metformin Therapy on Clinical and Hormonal Indices of Patients with Polycystic Ovary Syndrome

May 2021

Metformin helps manage weight, blood pressure, and hormonal imbalances in PCOS patients.

research MANAGEMENT OF ENDOCRINE DISEASE: Hyperandrogenism after menopause

84 citations , September 2014 in “European journal of endocrinology”

Doctors should check for serious tumor causes of high androgen levels in postmenopausal women and more research is needed on this condition.

research Subclinical hypothyroidism does not influence the metabolic and hormonal profile of women with PCOS

8 citations , June 2017 in “Hormone Molecular Biology and Clinical Investigation”

Mild thyroid issues don't affect the metabolism and hormones of women with PCOS.

research Insights learned from L457(3.43)R, an activating mutant of the human lutropin receptor

17 citations , October 2006 in “Molecular and Cellular Endocrinology”

The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.

Hypothyroidism in Polycystic Ovarian Syndrome: A Comparative Study of Clinical Characteristics, Metabolic and Hormonal Parameters in Euthyroid and Hypothyroid Polycystic Ovarian Syndrome Women

research Hypothyroidism in polycystic ovarian syndrome: a comparative study of clinical characteristics, metabolic and hormonal parameters in euthyroid and hypothyroid polycystic ovarian syndrome women

1 citations , January 2016 in “International journal of reproduction, contraception, obstetrics and gynecology”

Hypothyroidism may worsen metabolic problems like insulin resistance and obesity in women with PCOS.

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Community Join

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community Fresh off the press: Dutasteride may cause chronic infertility

in Research/Science 643 upvotes 1 year ago

Dutasteride may cause chronic infertility by reducing semen volume and motility, with concerns about irreversible prostate fibrosis. Users consider switching to finasteride or using treatments like minoxidil and microneedling, weighing hair preservation against fertility.

community Is there a topical androgen receptor blocker so we don't have to fuck with the enzyme and destroy our allopregnanolone, but go and hit the end target straight?

in Treatment 44 upvotes 2 years ago

The conversation discusses topical androgen receptor blockers for hair loss, mentioning Clascoterone, Pyrilutamide, GT20029, and RU58841. Ketoconazole's effectiveness and application methods are also debated.

community Fats on your Head to Stop Hair Loss?

in Research/Science 140 upvotes 2 years ago

The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

community Anyone else growing tired of the finasteride wars?

in Finasteride/Dutasteride 169 upvotes 2 years ago

The conversation is about differing experiences with finasteride for hair loss, with some users reporting side effects and others not, and the debate over the drug's safety and effectiveness. Specific treatments mentioned include finasteride, dutasteride, and topical finasteride.

community How is dht not beneficial to you?

in Finasteride/Dutasteride 111 upvotes 6 months ago

DHT is important for sexual function and mood, but finasteride and dutasteride can reduce DHT, causing side effects like reduced libido and erectile dysfunction. These treatments are effective for hair loss, but their impact on DHT leads to debate.

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