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      learn Pyrilutamide

      highly targeted anti-androgen that might have minimal systemic effects

      learn PP405

      mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

      learn Follistatin

      glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

      learn GT20029

      research compound made to degrade androgen receptors in scalp

      learn Exosomes

      Microscopic delivery system that sends growth-promoting signals to hair follicles

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      community Pp405 phase 2a clinical results

      in Research/Science  38 upvotes 9 months ago
      PP405 shows initial promise for treating androgenetic alopecia, with safety confirmed in early trials, but skepticism remains due to limited data. Further trials are needed to determine its true efficacy and potential market impact.

      community Pyrilutamide phase III clinical trial results released

      in Research/Science  31 upvotes 2 years ago
      Pyrilutamide did not show effectiveness in regrowing hair compared to a placebo, but it may still help maintain existing hair by preventing DHT from causing follicle miniaturization. Some users believe it could be beneficial when used with other treatments like minoxidil, finasteride, and dutasteride.