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research Sequence of the intron/exon junctions of the coding region of the human androgen receptor gene and identification of a point mutation in a family with complete androgen insensitivity.

32 citations , November 2020 in “UNC Libraries”

A point mutation in the androgen receptor gene causes complete androgen insensitivity.

research Editor's evaluation: Complementary evolution of coding and noncoding sequence underlies mammalian hairlessness

March 2022

Hairlessness in mammals is due to complex genetic changes in both genes and regulatory regions.

research Complementary evolution of coding and noncoding sequence underlies mammalian hairlessness

16 citations , November 2022 in “eLife”

Both gene and non-gene areas of DNA evolved to make some mammals hairless.

research Complementary evolution of coding and noncoding sequence underlies mammalian hairlessness

2 citations , March 2021 in “bioRxiv (Cold Spring Harbor Laboratory)”

Hairless mammals have genetic changes in both their protein-coding and regulatory sequences related to hair.

research Decision letter: Complementary evolution of coding and noncoding sequence underlies mammalian hairlessness

March 2022

Hairless mammals evolved quickly in both gene and non-gene areas related to skin and hair.

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community How likely do you think it is for PP405 to come out?

in Research/Science 21 upvotes 9 months ago

PP405 is a potential new hair loss treatment that works through metabolic pathways rather than hormonal ones, with an estimated market release between late 2027 and 2029. Current alternatives to finasteride include minoxidil, pyralutamide, fluridil, and RU58841, with hair transplants also being a viable option.

community UPDATE: The theory that explains everything. Please help me make this big!

in Research/Science 444 upvotes 5 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

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learn Stem Cell Factor

learn Thymosin Beta 4

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