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research 376 Tsc2 disruption in mesenchymal progenitors regulates hair follicles and TGF beta signaling

April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology”

Disrupting the Tsc2 gene in certain cells leads to thicker skin, larger hair, and changes in hair growth signaling, which can be partly reversed with specific treatment.

Dose-Dependent Histopathological and Structural Impact of Chemical Hair Straighteners on Scalp Epithelium and Hair Fibers Using Albino Wistar Rats

research Dose-Dependent Histopathological and Structural Impact of Chemical Hair-Straighteners on Scalp Epithelium and Hair-Fibres Using Albino Wistar Rats

September 2025 in “Sahel Journal of Life Sciences FUDMA”

Chemical hair straighteners can severely damage hair and scalp with repeated use.

research Dandelion-Derived Carbon Dots with pH-Responsive Charge and Dual ROS Regulation for Anti-Infection and Accelerated Wound Repair

June 2026 in “ACS Applied Materials & Interfaces”

Dandelion-derived carbon dots effectively kill bacteria and speed up wound healing.

research Gorab deficiency in skin dermis accelerates aging and is associated with dysregulation of RCHY1 ‐mediated P53 ubiquitination

March 2026 in “Animal Models and Experimental Medicine”

Gorab deficiency speeds up skin aging by disrupting protein regulation and reducing collagen.

Immunohistochemical Insight Into the Association Between the Collapse of Immune Privilege in the Sweat Gland and Syringotropic Immune Cell Infiltrates in Collagen Diseases

research 259 Immunohistochemical insight into the association between the collapse of immune privilege in the sweat gland and syringotropic immune cell infiltrates in collagen diseases

September 2017 in “Journal of Investigative Dermatology”

The study found that sweat glands normally suppress immune responses, but this is disrupted in certain skin diseases, possibly contributing to their development.

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community Minoxidil inhibits lysyl hydroxylase which is needed to produce collagen. If I take 2,5...5 mg of minoxidil every day can I cause my skin to age prematurely?

in Minoxidil 32 upvotes 1 year ago

Oral minoxidil is effective for hair loss and unlikely to significantly affect collagen synthesis, making it a safe option without causing premature skin aging. Users report positive hair regrowth without noticeable skin aging.

community microneedle, any long term users damage?

in Microneedling 35 upvotes 2 years ago

Microneedling is effective for hair growth, especially when combined with finasteride and minoxidil, but concerns exist about potential long-term skin damage. Users report increased collagen and elastin deposition, but the long-term effects on the scalp remain uncertain.

community Which biotin and shampoo do people use? Too many options...

in Treatment 1 upvotes 5 years ago

The conversation discusses using Biotin 10000mcg with Keratin and DHT blockers for hair growth. The user seeks advice on other community-recommended options.

community Rejux-3x - the copper peptide combo that tressless overlooks.

in Research/Science 4 months ago

Rejuv-3X, a topical blend with GHK-Cu, AHK-Cu, and JXL-089, is used for hair loss, offering a targeted option without finasteride's side effects. The user plans to combine it with microneedling for enhanced results.

community Study Shows That Oral Minoxidil Is Not Only Good At Improving Hair But Also Reducing Arterial Stiffness And Preventing Other Health Problems

in Minoxidil 23 upvotes 5 years ago

Oral minoxidil may improve hair growth, reduce arterial stiffness, and prevent other health issues. Some users believe it is an effective treatment despite concerns about its effects on skin and blood.

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