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Microneedling over existing hair is discussed, with concerns about potential harm. Treatments mentioned include Minoxidil, finasteride, and RU58841.

A 26-year-old male is considering starting the "Big 3" treatments for hair thinning, which include Minoxidil, finasteride, and RU58841, and is unsure whether to begin these treatments or consult a dermatologist first.

A 20-year-old with no signs of hair loss is considering finasteride or dutasteride due to family history of baldness. Advice given is to monitor hair and start treatment only if thinning occurs.

A private clinic suggests starting with topical Minoxidil only, raising concerns about DHT blocking and potential side effects of Finasteride. The user is considering whether to follow this plan or use a combination of Minoxidil and Finasteride for hair thinning.

The user is experiencing hair loss with possible causes including chronic telogen effluvium, diffuse alopecia areata, and androgenic alopecia. They have tried treatments like Nizoral shampoo, minoxidil, and finasteride, and are considering a biopsy for further clarity.

Oral minoxidil and finasteride can change hair texture, making it drier or frizzier. Minoxidil is likely causing the roughness; adding a moisturizing treatment may help.

The user used minoxidil unnecessarily for two months due to a perceived hair loss but realized their hairline hadn't changed in 2.5 years. They are concerned about shedding caused by minoxidil and whether stopping its use will allow regrowth or cause permanent damage.

The user has been using finasteride for a year and recently started minoxidil, noticing reduced hair shedding but no significant regrowth. Suggestions include continuing the current regimen, adding micro-needling, and considering a hair transplant for more noticeable results.

The user experienced side effects from finasteride and found improved mood and performance with DHT, but it worsened hair loss. They are considering options like TRT, HCG, and topical treatments like Saw Palmetto, but struggle with balancing hair preservation and functionality.

A 22-year-old is frustrated with ongoing hair loss despite using treatments like topical minoxidil, finasteride, microneedling, oral dutasteride, and oral minoxidil. Their dermatologist suggests treating scalp inflammation with oral tretinoin and using exosomes for alopecia.

The user is experiencing hair loss with a receding hairline and has started using minoxidil. They are concerned about increased hair shedding after discontinuing a previous lotion.

The user plans to start finasteride treatment for hair thinning and seeks advice on dosage, specifically how many 1mg pills to take weekly. They have noticed hair loss in the shower and some receding at the hairline.

A 25-year-old male has been using 5% Minoxidil, 1.25 mg Finasteride, and weekly microneedling for hair loss but sees no improvement after a year. Despite a healthy lifestyle, his hairline continues to recede, and he seeks advice.

The user is experiencing hair loss and is concerned about a small bald patch despite having thick hair and a full crown. They are considering starting minoxidil and finasteride to prevent further hair loss.

The conversation is about starting microneedling for hair growth, with questions on needle sizes, session frequency, and reliable purchasing options. The user seeks clarity on FDA regulations and prefers to avoid certain online retailers.

Consider using finasteride or minoxidil for hair loss. Both treatments require patience as results may take months.

The conversation discusses using oral finasteride and oral minoxidil as potential treatments for hair loss. The user is seeking advice on whether these treatments could help their condition.

An 18-year-old is concerned about potential balding and seeks advice. They are unsure if their hairline is a widow's peak or if they are experiencing hair loss.

The user switched from finasteride to dutasteride eight months ago due to worsening hair loss but continues to experience hair thinning and seeks advice on additional treatments. They are asking for suggestions on medications, topical therapies, lifestyle changes, or professional treatments.

A 25-year-old is using finasteride for hair loss and plans to start minoxidil and ketoconazole shampoo soon. They hope to see hair regrowth and will continue to shave their head while monitoring progress.

The user experienced no regrowth after nine months on minoxidil and developed red bumps after starting finasteride. They also use Nizoral 2%, which helps slightly, but minoxidil causes intense itching.

The user underwent a hair transplant and was prescribed dutasteride and minoxidil for 6 months to address crown thinning. They are skeptical about the short duration and consider continuing the medication longer.

A 20-year-old with anxiety and depression is considering finasteride for hair loss but is worried about potential side effects. They decide to consult a doctor and consider starting with a low dose, while also exploring topical finasteride as a potentially safer option.

A 19-year-old male switched from finasteride and minoxidil to dutasteride due to continued hair thinning and is experiencing increased nipple sensitivity and a small lump, raising concerns about gynecomastia. Suggestions include slowing the transition, checking hormone levels, and considering an aromatase inhibitor.

The user is using oral Minoxidil 2.5 mg, oral Finasteride 1 mg, and a 2mm derma roller for hair loss but feels discouraged by the lack of results after a month. They are seeking advice and considering additional methods like antiandrogens, exercise, and dietary changes.

The user is considering buzzing their long hair to better assess the effects of finasteride, which they have been using for over two months, and is concerned about maintaining their unique appearance. They are also curious if dyeing short hair could cause any issues.

The user is using oral minoxidil for hair loss and is considering its effects on facial hair. They are advised that minoxidil can help with facial hair, but a DHT blocker like finasteride is needed for head hair.

The user discusses using dutasteride to stop hair loss and bimatoprost for regrowth. They plan to use VEGF with hydrogels for potentially permanent hair follicle improvement and suggest PRP as an alternative.

FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

USER19 shared progress pictures 1.5 years after a hair transplant of 4180 grafts by Dr. Ahmet Yildirim, with no medications used. New hair growth started after the 3rd month.