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      community Minox 3mg, Finasteride 1.2mg (6 month perfect adherence)

      in Progress Pictures  370 upvotes 2 months ago
      Significant hair improvement was achieved using 3mg Minoxidil and 1.2mg Finasteride over six months, with no side effects, leading to reconsideration of a hair transplant. A detailed skincare routine, including tretinoin and SPF, also improved skin appearance.

      community 1.25mg Finasteride (6times a week)

      in Finasteride/Dutasteride  3 upvotes 4 months ago
      A 25-year-old is using 1.25mg finasteride six times a week and 5% topical minoxidil daily for hair loss. They are experiencing reduced libido and erectile issues, possibly due to stress, and are questioning if the finasteride dosage is affecting DHT suppression.

      community 20M, 2.5 months, 1mg fin, topical min(local)

      in Progress Pictures  125 upvotes 1 year ago
      A 20-year-old male shares his 2.5-month progress using 1mg finasteride, topical minoxidil, tretinoin, dermarolling, and ketoconazole for hair loss, noting slight libido decrease. Users discuss sourcing topical finasteride and request more photos to see the results.

      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  133 upvotes 2 years ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community Any chemists want to manufacture PP405 / JXL069? (Steps inside)

      in Research/Science  89 upvotes 7 months ago
      The conversation discusses the synthesis and potential use of JXL069 and PP405 for hair loss treatment, with skepticism about their effectiveness and concerns about safety. Users mention that JXL069 has shown no results in hair growth, and there is confusion about its identity and effectiveness compared to PP405.

      community Joining clinical study for Clascoterone (Breezula)

      in Research/Science  7 upvotes 1 year ago
      The conversation is about a user considering joining a clinical study for Clascoterone (Breezula) after experiencing no results with topical finasteride and minoxidil, and side effects from oral finasteride. The user is seeking advice on clinical study participation and experiences.

      community Dutasteride mesotherapy help me !

      in Finasteride/Dutasteride  4 upvotes 8 months ago
      The user experienced side effects like watery semen, erection problems, and decreased libido from finasteride, which resolved after stopping it. They are considering dutasteride mesotherapy as an alternative, as advised by their dermatologist, and are concerned about potential side effects.

      community Low cortisol it is due the fin

      in Finasteride/Dutasteride  8 upvotes 11 months ago
      The user has been taking 1mg finasteride daily for a year with no improvement in hair loss and reports low cortisol levels, sleep issues, and anxiety changes. The conversation includes discussions on the potential effects of finasteride on cortisol and neurosteroids, with suggestions to consult a doctor and consider other factors.

      community cb-03-01 research chem (winlevi/clascoterone cream)

      in Technology  3 upvotes 2 years ago
      The user is considering using CB or clascoterone for hair loss, potentially as an alternative to RU. They're also contemplating asking a dermatologist for topical clascoterone cream to apply to their temple.

      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 1 year ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

      community 6.5 months 0.5-1.5mg d/Dut and 5-10mg OM. Have I regressed?

      in Progress Pictures  6 upvotes 1 year ago
      The user has been using various hair loss treatments, including dutasteride, oral minoxidil, finasteride, RU58841, and dermarolling, but feels they may have lost hair and is considering a hair transplant. They are advised to stick to one treatment for 6-12 months to see results, as frequent changes may hinder progress.

      community 23M Wierd blood test results after 7 months on finasteroid (1mg daily)

      in Finasteride/Dutasteride  5 upvotes 5 months ago
      A user experienced unexpected hormone test results after 7 months on 1mg daily finasteride, noting a decrease in estradiol despite expectations of an increase. Other users suggested that hormone responses can vary and that finasteride might still be effective if DHT levels are within range, while also mentioning factors like circadian rhythm and stress that could impact results.

      community 27M - look 2 months on Oral 3-in-1 - 1.1mg fin+5g min+ 1mg biotin

      in Progress Pictures  1397 upvotes 9 months ago
      A 27-year-old male experienced significant hair regrowth in two months using a daily oral 3-in-1 pill containing 1.1mg finasteride, 5mg minoxidil, and 1mg biotin from LockLab, with no side effects reported. The user also uses a derma-stamp twice a week to promote blood flow and stimulate growth.

      community 6 months before and after pics: VDPHL01 (oral minoxidil)

      in Progress Pictures  111 upvotes 1 year ago
      A user shared their positive experience with a clinical trial for a new oral medication, VDPHL01, which is a reformulated version of oral minoxidil taken at a high dose of 17mg daily, showing significant hair regrowth after six months. The user noted that this formulation is believed to be more effective and time-released, with fewer side effects compared to regular oral minoxidil.

      community Dutasteride causing us to have… girl babies?

      in Finasteride/Dutasteride  26 upvotes 3 years ago
      User Kylo313 used dutasteride for 20 years and had two daughters, questioning if dutasteride affects the likelihood of having male vs female children. Replies mostly request hairline photos and discuss anecdotal experiences, with some suggesting correlation doesn't imply causation and that gender determination isn't affected by dutasteride.

      community I think its working…. (23 years old 3 month treatment)

      in Progress Pictures  89 upvotes 1 year ago
      A 23-year-old is using oral dutasteride, topical minoxidil with finasteride, PRP, and microneedling for hair loss treatment over three months, showing noticeable progress. Some users suggest caution with hormonal treatments and discuss the cost-effectiveness of PRP.

      community New Latanoprost-Based Formula Used by Hollywood Celebrities

      in Treatment  26 upvotes 3 years ago
      A new Latanoprost-based formula used by Hollywood celebrities to treat hair loss, with the formula containing minoxidil, tretinoin, melatonin, azelaic acid, zinc thymulin, vitamin B6, sandalore and methyl vanillate. It also mentions the potential of offering a combined sublingual minoxidil/oral dutasteride option in the future.

      community 5MG finasteride everyday June 1st 2024 - October 7th 2024

      in Progress Pictures  182 upvotes 1 year ago
      The user has been using 1.25 mg of finasteride daily since June 2024 to promote hair regrowth and thickness, considering switching to dutasteride if results are unsatisfactory. They are hesitant to add minoxidil due to cost and potential side effects but have seen some progress with finasteride alone.