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The user experienced side effects with both oral and topical finasteride and is considering making their own hair loss treatment using CB-03-01 (Breezula) mixed with minoxidil due to fewer reported side effects. They plan to use a lower concentration than what was used in trials.

Finasteride can cause gynecomastia due to hormonal imbalances, and using an aromatase inhibitor like anastrozole can help manage these side effects. It's important to work with an endocrinologist to address these issues safely.

PP405's phase 2a trial results were presented, focusing on safety and pharmacokinetics, with a future meeting planned to share the full dataset. The trial includes a randomized controlled portion and an open-label extension, with no indication of phase 2B completion.

Hair loss discussion includes Minoxidil, Finasteride, and RU58841 treatments. Pyrilutamide cleared for phase 3 clinical trial in China.

A 23-year-old male has been using oral dutasteride and minoxidil for 1.5 years for temple recession, adding topical minoxidil and tretinoin 5-6 months ago, and recently adjusted thyroid medication and added iron supplements due to deficiencies. He noticed some baby hairs but no significant growth yet, and reports no shedding on dutasteride.

User experienced hair thickening with pyri but also side effects like reduced sex drive. Stopping pyri and returning to CB restored sex drive, suggesting pyri may go systemic or be incorrectly formulated.

KX-826 failed Phase III trials due to high placebo effects, patient compliance issues, COVID-19 side effects, and detection method deviations. KX-826 is now marketed as a cosmetic and approved for combination with Minoxidil.

PCOS female visited doctor for hair loss concerns, prescribed spironolactone and minox 5%. Doctor advised against finasteride or dutasteride, user considering self-medication with dutasteride.

Trans women discuss using finasteride and dutasteride for hair loss and whether to continue after testosterone suppression. One user reduced dutasteride dosage after achieving undetectable testosterone levels.

A 23-year-old male experienced significant hair improvement over 9 months using dutasteride, minoxidil, finasteride, PRP, and red light therapy, with no side effects. He plans to continue treatment for 6 more months before deciding on a hair transplant.

A user is seeking advice on making a topical bicalutamide solution as an alternative to RU58841 for hair loss, while already using dutasteride and minoxidil. They are considering crushing bicalutamide pills and adding them to their minoxidil.

The user shared 9-month results using a 4-in-1 spray containing finasteride, minoxidil, ketoconazole, and biotin, along with lifestyle changes like jogging, quitting smoking, and using collagen supplements. They also incorporated dermastamping, dermarolling, and various oils into their routine, reporting positive hair regrowth.

A user from China is participating in a clinical trial for Pyrilutamid, a potential hair loss treatment originally developed for prostate cancer. They've experienced no side effects except initial scalp itchiness, and will share results after the year-long trial.

The user has been using 0.5 mg oral finasteride and recently switched to 2.5 mg oral minoxidil from topical application. They are observing potential early regrowth with longer baby hairs.

A user is experiencing hair regrowth after 2.5 months using dutasteride and a daily spray containing finasteride, minoxidil, biotin, and ketoconazole. They are optimistic about continued progress and have noticed new dark hairs forming.

A 20-year-old used 1 mg finasteride and liquid minoxidil, initially twice daily then once at night, to thicken hair, though temple regrowth was minimal. The user experienced no side effects and continued both treatments for hair improvement.

The user "baselinesims" shared their progress in treating hair loss using 1mg oral finasteride, 1ml topical minoxidil, 0.5ml topical dutasteride, keto shampoo, cosmerna, and micro needling. They are happy with the progress so far, with diffuse thinning being taken care of and baby hairs showing up. They plan on getting a hair transplant in the future. Other users commented on the improved appearance and mentioned that the lighting in the photos may affect the comparison.

A user shared their 9-month progress using RU58841 at 2% daily for hair regrowth, initially starting at 5% but reducing the dose due to early signs of gynecomastia, which has since mostly resolved. They achieved their goal of regrowing hair at the temples and hairline.

The user has been using finasteride, minoxidil, and needling for 11 months with limited progress and plans to add sulforaphane for 3 months. Another user suggested trying Procyanidin B2 for better results.

A 22-year-old male started taking finasteride a month ago and is seeing some progress in hair loss treatment. He is concerned about high estradiol levels but plans to continue the medication and consult an endocrinologist.

The user experiences severe side effects from finasteride and dutasteride, including low libido and anxiety, and is currently using oral minoxidil despite shortness of breath. They are seeking alternative treatments for hair loss, having tried pyrilutamide, fluridil, and RU58841 with no success, and are considering future treatments or a hair transplant.

Hair loss discussion includes treatments like hinoki tree oil and procyanidin b2. Experiences and effectiveness of these treatments are shared.

The user is allergic to minoxidil and plans to try Redensyl hair serum and derma rolling for hair regrowth. They cannot start finasteride until age 18.

The user is taking a 2-in-1 pill containing 1mg finasteride and 3mg minoxidil daily, noticing some hair thickening and new hair growth but minimal progress at the back of the head. They are considering adding topical minoxidil or increasing dosage and are unsure if they should change their routine or wait for more results.

The conversation is about choosing an anti-androgen for hair loss treatment, with options being alfatradiol and pyrilutamide. Alfatradiol is considered a better choice due to its established use, while pyrilutamide is more experimental.

Theaflavin, a black tea extract, may inhibit DHT and androgen receptor activity, but its effectiveness for hair loss is debated. Users report no significant improvement with theaflavin, while some find beta sitosterol helpful.

Increasing the dutasteride dose to 2.5 mg may significantly reduce DHT and promote hair regrowth, with similar side effects to lower doses. Some users combine dutasteride with minoxidil and finasteride for better results, but there are concerns about long-term effectiveness and availability.

A user is seeking a titanium dioxide-free finasteride pill due to health concerns. They have not found a suitable supplier yet.

KX-826 (Pyrilutamide) being tested in the US for hair loss treatment and that they have found enough people to participate in phase II clinical trials. Other treatments discussed are Minoxidil, finasteride, and RU58841.

A user applied the 8T3 product for hair loss, targeting LPP and AGA, and plans to update on its effectiveness. The product uses a saline buffered phosphate vehicle, suitable for those intolerant to ethanolic vehicles.