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community We need actual hair loss studies on Epristeride

in Research/Science 6 upvotes 1 year ago

Epristeride is a selective 5 alpha reductase type 2 inhibitor that may reduce scalp DHT similarly to finasteride, with potentially fewer side effects. It is suggested that combining epristeride with finasteride or dutasteride could enhance hair loss treatment effectiveness.

community Phase II topical dut study - outperforms oral fin with a minor DHT reduction

in Research/Science 61 upvotes 4 months ago

Topical dutasteride 0.05% is more effective for hair growth than oral finasteride 1mg, with minimal DHT reduction. The formulation uses castor oil and MCTs for better absorption but is not widely available until 2028.

community M29 Dut/Min/Microneedle/Tretinoin

in Is this regrowth? 22 upvotes 1 year ago

A user has been using finasteride since 2018, switched to dutasteride, and added minoxidil, microneedling, and a tretinoin/spiro compound. They are pleased with the results and hopeful for more improvement.

community Liquid minoxidil + pyrilutamide

in Treatment 17 upvotes 3 years ago

Potential treatments for hair loss, specifically the combination of liquid minoxidil and pyrilutamide, with some suggesting that adding finasteride may be beneficial.

community Clascoterone 5% Delivers Strong Phase 3 Hair-Growth Results

in Research/Science 369 upvotes 5 months ago

Clascoterone 5% solution shows strong potential for hair growth, offering a new treatment for alopecia with minimal side effects. It blocks androgen receptors locally and may be available by late 2026 or early 2027.

community Best homemade topical Finasteride formula ?

in Treatment 3 upvotes 3 years ago

The conversation discusses homemade topical finasteride formulas, comparing two solutions with different proportions of alcohol and propylene glycol. The user seeks advice on which formula is gentler on the scalp, suggesting that less alcohol might be better.

community Curious about 'nuclear' stacks

in Research/Science 1 upvotes 1 year ago

The conversation discusses using higher doses of minoxidil and finasteride, considering dutasteride, and exploring other treatments like RU58841 for hair preservation. The user reports no side effects after six months and is interested in advanced treatment combinations.

community 30M, 15 months Dut 0,5 and prp, what now?

in General 202 upvotes 9 months ago

A 30-year-old male has been experiencing hair loss despite using Dutasteride 0.5mg and PRP for 15 months, with no success. He is considering a hair transplant but is advised to stabilize hair loss first and explore other treatments like topical Minoxidil or combined therapies.

community 23-Year-Old Trans Male: Concerns About Minox and Finasteride for Hair Loss

in General 298 upvotes 10 months ago

A 23-year-old trans male is concerned about hair loss and is considering treatments like topical and oral minoxidil and finasteride. They are worried about the effects on their pet and hormone balance and are seeking affordable options within their existing medical team.

community Studies show: 0.2 mg reduces scalp DHT by ~55%. 1 mg reduces it by ~64%. 5 mg reduces it by ~69%.

in Finasteride/Dutasteride 148 upvotes 8 months ago

Finasteride reduces scalp DHT significantly even at low doses, with 0.2 mg reducing it by about 55%, but higher doses like 1 mg and 5 mg offer only marginally more reduction. Users discuss side effects, with some experiencing none and others reporting issues like low libido, and they also mention using other treatments like minoxidil and dutasteride.

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