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      PP405 Identity Research

      community PP405 Identity Research

      in Research  292 upvotes 11 months ago
      PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.

      community clascoterone powder to topical diy

      in Product  3 upvotes 3 months ago
      The conversation is about making a topical solution from clascoterone powder, with references to using a RU58841 mixing guide for guidance. Concerns about product authenticity and bulk purchase requirements are also discussed.

      community 6 months progress topical min/fin (19)

      in Progress Pictures  99 upvotes 1 year ago
      The user is using a treatment of topical minoxidil 7% and finasteride 0.1% twice daily, along with a low-level laser therapy cap, biotin, and collagen supplements, and is seeing good progress on the hairline and temples but not the midscalp. They experienced initial shedding, saw results by month three, and are happy with the progress, though some users express concern about using finasteride at a young age.

      community Temple revival. Dropping Oral min.

      in Chat  4 upvotes 1 year ago
      The user experienced negative side effects from oral minoxidil, including cardiac issues and excessive sweating, and decided to switch to topical minoxidil while using other treatments like RU58841, Setipiprant, Azelaic acid, and latanoprost. Another user suggested splitting the oral minoxidil dose to reduce side effects.

      community 0.25 % fin and 0.25% dut together topically

      in Treatment  3 upvotes 7 months ago
      The user is dissatisfied with the results of using 0.3% finasteride and 6% minoxidil for hair thinning and is considering a topical treatment combining finasteride, dutasteride, minoxidil, melatonin, caffeine, and latanoprost. Another user suggests that high topical concentrations can lead to systemic exposure and recommends using oral dutasteride and microdosing topical finasteride.

      community Possibility of updates or more information on the pp405

      in Chat  19 upvotes 9 months ago
      The conversation discusses the potential updates on the pp405 trial for hair loss, with completion expected by December 2025. Participants express skepticism about new treatments, suggesting continued use of finasteride, while others hope for innovative solutions beyond current medications.

      community 5 months topical minox 5% /fin 0.1%

      in Update  1 upvotes 2 years ago
      User applied topical Minoxidil 5% and Finasteride 0.1% daily, with rosemary oil weekly, and saw initial baby hair growth. They plan to add derma stamping and Redensyl serum.

      community Regimen update - Added oral Minox and RU

      in Is this regrowth?  21 upvotes 3 years ago
      The user updated their hair loss treatment to include daily dutasteride, oral minoxidil, topical dutasteride with minoxidil and tretinoin, and RU58841. Commenters feel the extensive treatment is unnecessary for the user's level of hair loss.

      community So happy with results! 4 months

      in Progress Pictures  115 upvotes 1 year ago
      The conversation is about a user experiencing positive hair regrowth results after using finasteride, minoxidil spray, dermapen, and low-level light therapy (LLLT) for four months. The user recommends using a specific device for LLLT and mentions using the Hims spray for finasteride and minoxidil.

      community Fin+Tret+Min 4 month progress pics

      in Progress Pictures  8 upvotes 1 year ago
      The conversation is about hair loss treatment progress using a combination of 0.1% finasteride, 0.025% tretinoin solution, and 2.5mg oral minoxidil. Users express positive reactions and hope for similar results.

      community Dealing with Retrograde Alopecia

      in Treatment  6 upvotes 4 years ago
      User on Dut, oral minox 20 mg, Saw Palmetto, Pumpkin Oil, RU, 8% topical minox, and topical fina for hair loss; top of head improves, but retrograde alopecia worsens. Asks for options besides exosomes and where to find topical melatonin.

      community finasteride microneedling and exosomes

      in Finasteride/Dutasteride  4 upvotes 2 years ago
      The conversation is about a 21-year-old using finasteride, dermarolling, ketoconazole shampoo, hair growth serums, and exosome therapy to treat early-stage thinning on the crown. They are questioning if these treatments are sufficient to improve hair thickness.

      community Eucapil sale on, I'm giving it a go

      in Research/Science  7 upvotes 5 years ago
      Exploring treatment options for male pattern baldness, including minoxidil, finasteride, and RU58841, with a focus on Eucapil, a topical agent. The post also discusses research from various sources about the efficacy of these treatments.

      community 4600 - result 9 month - Dr. Carman

      in Progress Pictures  254 upvotes 2 years ago
      A user shared their 9-month post-hair transplant results with 4600 grafts, using only Nourkin hair vitamins, Vitamin D, and B12, and expressed satisfaction. The replies debated the necessity of medications like finasteride and minoxidil for maintaining hair health.

      community If PP405 goes systemic this would be quite catastrophic

      in Research/Science  4 upvotes 1 year ago
      Concerns about the potential systemic effects and safety of PP405 for hair loss, with discussions on its comparison to existing treatments like finasteride and minoxidil. Users express skepticism about untested research chemicals and emphasize the importance of clinical trials to ensure safety and efficacy.

      community 4 months .5 Dut and 3 months 2.5 Minox update

      in Progress Pictures  24 upvotes 10 months ago
      The user reports positive results from using 0.5 mg dutasteride daily for four months and 2.5 mg oral minoxidil for three months, with no side effects. They switched from topical minoxidil to this oral combination.

      community Any topical melatonin users here ?

      in Treatment  4 upvotes 3 years ago
      The conversation discusses using topical melatonin for diffuse thinning and mentions treatments like Minoxidil, finasteride, and RU58841. The user is seeking advice on whether melatonin could help with their condition.