Pumpkin Seed Oil and Perilla Oil (with alpha-lipoic acid, linoleic acid, and oleic acid) are discussed as potential 5alpha-reductase inhibitors. The conversation focuses on their effectiveness for hair loss treatment.
The conversation discusses hair loss treatments, specifically Stemoxydine from Vichy, and mentions alternatives like Minoxidil, finasteride, and RU58841. The user is seeking a more affordable option than L'oreal Serioxyl.
A 27-year-old male with Norwood grade 5 hair loss is using dutasteride and a hair serum with Redensyl, Anagain, Procapil, and Capilia Longa, but is hesitant to use oral minoxidil due to past allergic reactions to topical minoxidil. He plans to try dutasteride alone for 3 months before considering adding oral minoxidil.
A 30-year-old male is using a regimen of dutasteride, minoxidil, ketoconazole shampoo, tretinoin cream, and microneedling for hair regrowth. He reports no side effects and has noticed visual improvement after one month.
A user has been taking finasteride 1mg for 10 years without side effects but is concerned about high estradiol levels affecting weight loss. Another user suggests using estradiol blockers under medical supervision to manage the levels.
User discusses group buy for finerenone, a third-gen mineralocorticoid antagonist for hair loss treatment. Finerenone inhibits TGFb, NOX, and ROS, and improves renal and cardiac function; topical dose should be no more than 10mg per day.
Minoxidil's effectiveness varies due to differences in sulfotransferase enzyme levels in the scalp, affecting people with conditions like ASD, liver disease, and androgenic alopecia. Treatments like topical tretinoin, microneedling, and using minoxidil sulfate instead of regular minoxidil can improve results for those with low enzyme levels.
A user discusses using a mixed solution with minoxidil 2%, hydrocortisone butyrate, and estrone in the morning, and considering adding 5% minoxidil at night. They also use Restax softgel but avoid finasteride.
The user has been using finasteride and oral minoxidil for hair loss, but experienced increased hair loss after using testosterone steroids without post-cycle therapy. They are considering switching to dutasteride and have added ketoconazole shampoo to their routine, but are concerned about side effects and the ongoing hair loss.
A 23-year-old male experienced hair regrowth by adding oral minoxidil to his regimen, which already included dutasteride, topical minoxidil, ketoconazole shampoo, and levothyroxine. He also uses microneedling, biotin vitamins, and exercises regularly, reporting no side effects from oral minoxidil so far.
A trans woman is using 10 mg oral minoxidil, dutasteride, and estradiol for hair regrowth and is also doing dermastamping despite the pain. Users discuss the benefits of dermastamping for serum absorption and hair follicle stimulation, with some expressing surprise at the high minoxidil dosage.
User started using Pantostin Alfatradiol after watching haircafe on YouTube and noticed thicker hair. They wonder why it's not more popular, as it's a 5α-reductase inhibitor with a different mechanism than minoxidil.
The user has been using finasteride, minoxidil, retinoid, and occasional microneedling for hair loss with good results. They recently added stemoxydine, which improved their hair further, and suggest trying it, especially in the EU where it's easily available.
Hair loss treatment with topical finasteride/minoxidil, which had good results after 3.5 months of application. The user also asked if there was any reason to take the oral pill version and if anyone has ever tried mixing them together.
The conversation discusses using oral spironolactone for hair loss in males when 5ari blockers fail. Concerns are raised about spironolactone's side effects, and alternatives like pyrilutamide and breezula are suggested.
A 33-year-old man shares his positive hair regrowth results using 1mg finasteride daily, 5% topical minoxidil twice daily, and a 0.5mm dermaroller weekly. He feels more confident and encourages others to try the routine despite potential side effects.
Orsobalorso took 2.5mg oral minoxidil daily for a year but saw little improvement and stopped due to potential side effects and cost. They also tried finasteride, dutasteride, dermarolling, RU58841, keto, alfatradiol, and stemoxydine, with mild improvement from finasteride.
User asks about topical spironolactone experience. Two studies show it as promising anti-androgen treatment, with 5% cream available on Minoxidilmax website.
Concerns about the long-term safety of VDPHL01, an extended-release minoxidil, due to potential risks similar to Cantu syndrome, were raised, highlighting the lack of monitoring for chronic connective tissue changes. The conversation suggests that while the treatment may improve hair growth, it could lead to issues not detected in short-term trials.
A user shared their 1-year and 3-month hair loss treatment progress using 0.5mg Dutasteride daily, topical and then oral Minoxidil, and microneedling, noting hair darkening and some side effects like watery semen and testicular pain. Despite initial setbacks after switching to oral Minoxidil, they are seeing progress and plan to increase the dosage.
The user is experiencing some hair regrowth after six months on oral minoxidil (3mg), finasteride (1.2mg), and using 1% ketoconazole shampoo twice a week, with no side effects. They are advised to consult a doctor before adjusting doses and to consider blood tests for vitamin and mineral levels.
Veradermics' extended-release oral minoxidil is expected to be commercially available in 2027-2028, while another company, Minx, may release a similar product sooner. VDPHL01 is considered more clinically validated compared to Minx.
A user shared their 3-month progress using oral minoxidil, finasteride, and topical minoxidil for hair loss. Another user commented on the significant improvement, hoping for similar results.
A 21-year-old male shares a 3-month progress update using 1 mg oral finasteride daily and 5% topical minoxidil twice daily, reporting no side effects and noticeable hair growth. Users commend the results and encourage continuation of the treatment.
Combining dutasteride and an aromatase inhibitor may increase testosterone levels significantly, potentially enhancing athletic performance but also posing health risks like elevated blood pressure and worsened cholesterol. The user is experimenting with dutasteride, anastrozole, minoxidil, and ketoconazole shampoo to manage hair loss and estradiol levels, while monitoring side effects and hormone levels.
The user has been using finasteride, dutasteride, pyrithione zinc, and oral minoxidil to treat hair loss and has seen an increase in fine hairs on the hairline but overall thinning on the top. They are considering adding zinc and Vitamin K to their regimen and are already taking hair multivitamins with collagen.
User restarted hair loss treatment with consistent finasteride, minoxidil, ketoconazole shampoo, and weekly dermarolling. Another user shared their regimen including dutasteride, oral minoxidil, RU58841, derma roller, ketoconazole shampoo, and stemoxydine.
The user has experienced limited hair regrowth using 1mg oral finasteride, topical minoxidil foam, and occasional dermarolling since August 2023. They are considering switching to dutasteride, adding oral minoxidil 2.5 mg, and RU58841 to improve results.