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      community PP405 Hair Loss Drug: Phase 1 Human Results & Biopsy Insights

      in Research/Science  213 upvotes 1 year ago
      PP405 is a potential hair loss treatment undergoing trials, with discussions on its effectiveness and comparison to existing treatments like finasteride and minoxidil. There is skepticism about its status as a cure, with hopes for future advancements in genetic treatments like CRISPR.

      community 15 months on the Big 3! My journey so far…

      in Progress Pictures  162 upvotes 3 years ago
      A user's progress after 15 months of using the "Big 3" treatments for hair loss (finasteride, minoxidil and micro needling) as well as Nizerol 2%. The post encourages others to seek out available information on hair loss treatment and reassures them that if it doesn't work, it is only hair.

      community Diffuse thinning is the worst man

      in Chat  248 upvotes 2 years ago
      The conversation is about the struggles of dealing with diffuse thinning at a young age and the lack of significant improvement after using treatments like finasteride and minoxidil. Some suggest additional methods like derma rolling, microneedling, and hair fibers, while others share their own experiences and encourage persistence with treatment.

      community Brief update clascoterone phase 3 - Breezula

      in Research/Science  4 upvotes 2 years ago
      Cosmo Pharmaceuticals has enrolled about 850 out of 1400 patients for their phase 3 clinical trials of clascoterone (Breezula) and claims to be on schedule. The conversation is about hair loss treatments.

      community Creating a custom topical growth serum

      in Research/Science  6 upvotes 1 year ago
      A user is creating a custom topical hair regrowth serum using minoxidil, bimatoprost, tretinoin, castor oil, and hyaluronic acid. They are also using dutasteride, oral minoxidil, and castor oil in their current regimen.

      community 3 months of hair treatment! I think I’m hyper responsive to my treatment. Finasteride, biotin pills, derma roller with rosemary/jojoba oil applied after, coffee in the morning for caffeine . No diet or alcohol consumption changes.

      in Progress Pictures  491 upvotes 2 years ago
      The user reports significant hair regrowth after three months using finasteride, biotin pills, a derma roller with rosemary/jojoba oil, and drinking coffee, despite an initial increase in hair shedding. Other users share varied results with similar treatments, with some not experiencing improvements.

      community Group Buy for MR antagonist finerenone

      in Product  11 upvotes 2 years ago
      User discusses group buy for finerenone, a third-gen mineralocorticoid antagonist for hair loss treatment. Finerenone inhibits TGFb, NOX, and ROS, and improves renal and cardiac function; topical dose should be no more than 10mg per day.

      community a new supplement just released

       11 upvotes 8 years ago
      A dermatologist recommended a new supplement containing annurca apple, which reportedly doubles hair density and increases keratin after 60 days, to be used with finasteride. Some users are skeptical, considering it potentially ineffective or a marketing ploy, while others are open to trying it if it proves effective and affordable.

      community 3 months update (oral fin/min 1.2/3mg)

      in Progress Pictures  10 upvotes 3 months ago
      The user started using finasteride and minoxidil in October 2025 and noticed hair growth and thickening after three months, despite initial concerns about side effects. They are hopeful for continued progress and grateful for the support from the forum community.

      community 3 Months update - cannot believe it

      in Progress Pictures  1553 upvotes 8 months ago
      A user shared their positive experience with hair regrowth after three months using topical minoxidil twice daily, 1mg finasteride every morning, and microneedling every 10 days. They reported no side effects and encouraged others to consider similar treatments.

      community Updates about KX-826 & GT20029

      in Research/Science  16 upvotes 3 years ago
      The conversation discusses potential advancements in two hair loss drugs, KX-826 and GT20029, and the interest in whether transitioning from oral finasteride to these drugs would maintain hair growth. One reply expresses skepticism about the compounds' representation.

      community KX-826 Phase 3 Failed. Sorry guys...

      in Research/Science  50 upvotes 2 years ago
      The conversation discusses the failure of Phase 3 trials for the hair loss treatment KX-826, with no significant difference found between the drug and placebo. Some users express disappointment and skepticism, while others discuss alternative treatments like Minoxidil, finasteride, and RU58841.

      community 4 month update - nuclear stack, 42m

      in Progress Pictures  256 upvotes 1 year ago
      A 42-year-old user shared a 4-month update on their hair regrowth using a "nuclear stack" including oral and topical minoxidil, dutasteride, RU58841, micro-needling, keto shampoo, saw palmetto, biotin, multivitamins, scalp massages, and inversion table. They reported significant progress with minimal side effects and plan to continue the routine.

      community Status update on upcoming treatments

      in Technology  43 upvotes 3 months ago
      Current treatments for hair loss include finasteride, minoxidil, and derma rolling. New treatments like Breezula, PP405, and others are not expected until at least 2027 or later.

      community 3 Month Update (Top Minox/Oral Fin/Stamp/Vitamin D)

      in Update  22 upvotes 6 months ago
      The user reports noticeable hair growth progress after three months using topical Minoxidil, oral Finasteride, microneedling, and Vitamin D. Encouragement and additional advice, like using keto shampoo, are given by others.

      community Guys hear me out we might have a breakthrough

      in Satire  665 upvotes 2 years ago
      The conversation is a satirical discussion about unconventional hair loss treatments, including using mold, butter, and other non-traditional substances, with no real evidence of effectiveness. Some users joke about side effects like erectile dysfunction and weight gain.

      community Pre styler thickening clay recommendation

      in Product  2 upvotes 4 months ago
      The user recommends a thickening clay as a great pre-styling product for hair volume and texture, despite its poor hold. They also mention using finasteride and express skepticism about the effectiveness of a shampoo containing saw palmetto and caffeine.

      community Thoughts on this 2-deoxy-D-ribose Topical?

      in Treatment  27 upvotes 1 year ago
      The post and conversation are about skepticism towards a new hair loss treatment containing 2-deoxy-D-ribose, copper peptides, and exosomes, with concerns about the legitimacy of the product and its website. The treatment's effectiveness and authenticity are questioned due to lack of testing and transparency.

      community can someone help me identify these pls

      in Treatment 4 months ago
      The user is experiencing diffuse thinning and inflammation despite using 2.5mg dutasteride daily, ciclopirox, and ketoconazole shampoos. They are considering treatments like hydroxychloroquine and JAK inhibitors due to suspected scarring alopecia and have faced challenges in obtaining a scalp biopsy.

      community ~3 year update on my singular DHT immune hair for you guys

      in Update  20 upvotes 2 years ago
      The post is an update on the user's hair loss journey. They have a strong hair follicle that has remained unaffected by hair loss for almost 3 years. The user is starting finasteride and using ketoconazole, alfatradiol, and oral castor oil for hair maintenance.

      community My 3 month 'progress' so far. I feel like it's working.

      in Progress Pictures  9 upvotes 3 months ago
      The user is experiencing positive hair growth after 3 months using 0.5mg dutasteride, 2.5mg oral minoxidil, topical minoxidil, dermastamping, and biotin shampoo, with some side effects like reduced libido and palpitations. They plan to continue treatment for a year before considering a hair transplant, as advised by another user who suggests waiting for full results from minoxidil and finasteride.

      community Crown recovery update - 7 months of treatment

      in Progress Pictures  1035 upvotes 10 months ago
      A 29-year-old reports positive hair recovery after 7 months using liposomal topical finasteride and minoxidil, low-level light therapy, and vitamins, following a 3600 graft DHI procedure. They experienced no side effects from the topical treatment, unlike with oral finasteride.

      community Estradiol mesotherapy / idea feedback

      in Female  7 upvotes 1 year ago
      The conversation discusses using estradiol mesotherapy to replicate hormone replacement therapy results while minimizing systemic exposure. It also covers the use of Spironolactone cream, which reportedly has no systemic side effects, and the potential risks of using bicalutamide and Spironolactone in men.