Search

everythinglearnresearchcommunity

for

Search:↓

Significant hair regrowth was achieved using a topical combination of 0.3% finasteride and 6% minoxidil, with weekly dermastamping and ketoconazole shampoo, without side effects. Others suggested additional treatments like red light therapy and PRP.

Tretinoin can make minoxidil more effective for hair loss treatment, but some users did not see improved hair density with this combination and had better results with dutasteride.

PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.

A 23-year-old male shared his 4-month progress using a topical spray with 0.3% Finasteride, 7% Minoxidil, 2.2% Ketoconazole, and 0.2% Biotin, along with microneedling. He noticed new hair growth on his temples and experienced initial shedding, with no significant side effects after the first month.

A user shared their 3.5-month progress using 1 mg oral finasteride daily, 5% topical minoxidil nightly, and a dermaroller weekly, reporting no side effects. Others congratulated the user on their progress and inquired about side effects, to which the user confirmed experiencing none.

A 25-year-old is using a combination of oral minoxidil, finasteride, RU58841, and topical dutasteride mixed with minoxidil to combat hair loss and hopes to see regrowth. They plan to update on the effectiveness of this regimen in a few months.

The user is using topical finasteride (1MG in 30ML stemoxydine) and experiencing a lack of morning erections after three months. They are questioning whether to discontinue the treatment or if the side effect will resolve if they continue.

A user discusses using latanoprost, a costly treatment that may extend the hair growth phase and improve hair quality, wondering why it's not more popular. They already use a combination of finasteride and minoxidil and plan to incorporate latanoprost into their routine.

Hmi115, a prolactin receptor blocker, showed promise for hair growth, but results from Phase 2 trials have not been published. ABS-201, an AI-based analog, is expected to begin trials in December 2025, while commercialization of treatments like PP-405 is anticipated around 2027.

Minoxidil increases hair count despite high prolactin being linked to hair loss. Blocking DHT is effective, but not always necessary; HMI-115 is a promising treatment for androgenetic alopecia.

PP405 shows promise for hair regrowth, with new hairs observed in 66% of patients in just 27 days. The discussion also mentions Minoxidil, finasteride, and RU58841 as potential treatments.

The user is considering using topical finasteride for hairline recession and thinning, despite having low DHT levels and previous side effects from oral finasteride. They are also taking 2.5 mg of oral minoxidil, which has not resulted in regrowth or stabilization.

The user does not respond well to minoxidil and is seeking an alternative to Tretinoin to upregulate sulfurtransferase activity for hair loss treatment. No specific alternative treatments were mentioned.

The user tried minoxidil 5% for 3 years with little improvement, then switched to a 15% minoxidil with 0.1% finasteride solution once daily and started using pyrilutamide, resulting in significant hair regrowth over time. They are considering a hair transplant but are continuing with topical treatments to maximize hair growth first.

The user noticed new baby hairs after using sulforaphane but is still experiencing shedding. They are seeking a supplement to stop shedding, possibly grape seed extract.

The user is trying RU58841, oral minoxidil, and dermarolling to combat hair loss caused by increased scalp testosterone after using finasteride and dutasteride. They plan to document their results.

A 28-year-old male has been taking 1mg finasteride daily since January 26, 2024, with noticeable hair regrowth and no side effects. He also takes Vitamin D3 and a multivitamin daily and advises others to try finasteride despite potential side effects.

The conversation discusses the potential benefits of castor oil for hair thickening, with one user noting it may increase prostaglandin E2 and decrease PGD2. The original poster plans to take 1-2ml orally daily.

A user shared a new hair loss treatment protocol including topical dutasteride, latanoprost, caffeine, minoxidil, tretinoin, and triamcinolone acetonide. Others discussed the effectiveness and availability of these treatments, with some suggesting simpler oral alternatives.

The user experienced significant hair regrowth by returning to a regimen of 1mg oral finasteride daily and daily topical minoxidil after previously reducing their doses. They also emphasize maintaining energy and health through diet, exercise, and supplements.

The conversation discusses the lack of public information on the chemical structure of PP405, a hair loss treatment, and the challenges of synthesizing it without a patent. It also explores a patent related to hydrogen-based topical formulations for reducing oxidative stress and inflammation.

A 35-year-old male has been using finasteride inconsistently for two years and is hesitant about using minoxidil due to potential side effects. He is considering oral minoxidil and microneedling as alternatives and is unsure if dutasteride is too strong.

The user shared a 3.5-month hair regrowth update using finasteride, 5% topical minoxidil, micro-needling, and keto shampoo, along with lifestyle changes like reducing stress and improving diet. They encourage others to stay committed to their regimen despite initial slow progress.

The user is experiencing breast tissue growth from taking dutasteride and minoxidil, and is considering reducing the dosage or stopping the medication. Suggestions include seeing an endocrinologist, using Raloxifene or Arimidex, and considering topical treatments or surgery if necessary.

PP405 shows promise for hair regrowth by manipulating stem cell characteristics and lactate dehydrogenase, with Phase 2a trials pending. Google Ventures' $15M investment suggests confidence, but results and market availability remain uncertain.

The user is frustrated with their lack of hair growth after 3.5 months of using minoxidil, dermarolling, Propidren (Saw Palmetto), and essential oil massages. They are hesitant to use finasteride due to potential side effects, despite suggestions that it might be more effective.

Using retinol with minoxidil may not be as effective as tretinoin, but retinaldehyde or adapalene could be alternatives. A micro-roller with minoxidil is suggested for better results.

A 27-year-old male has been using oral minoxidil and topical finasteride for 3 months, noticing fuller, thicker hair with no side effects. Users discuss the effectiveness and side effects of oral versus topical treatments, with some recommending higher doses or additional treatments like topical minoxidil.

Bimatoprost 1% and 3% solutions showed better hair regrowth than minoxidil 5%. The user plans to test a homemade bimatoprost solution on their scalp and share results.

Clascoterone is being discussed for hair loss, but its current acne formulation may not be suitable for scalp use due to potential skin irritation and lower dosage compared to Breezula. Users mention other treatments like finasteride, minoxidil, and pyrilutamide, with some expressing skepticism about clascoterone's effectiveness for hair loss.