OP uses microneedling, Minoxidil, and recently started RU58841 for hair loss. Users suggest adding finasteride, but OP is concerned about side effects.
Results for PP405 are expected next year, with concerns about its pricing and potential black market availability. Some users believe it may be slightly more effective than finasteride and dutasteride, and combining it with treatments like minoxidil and microneedling could be beneficial.
The user "Expliced" shared their progress pictures after using finasteride, minoxidil, and microneedling for 1 year and 3 months. Another user mentioned that using a high-definition camera with flash and sharpening the photo can show new hairs appearing sooner.
Microneedling alone has limited effectiveness for hair growth, but it may enhance the results of topical minoxidil. The optimal needle length varies, and while some users report benefits, others see no significant change without additional treatments.
Nanoxidil is considered to have better absorption and fewer side effects than minoxidil, with added DHT blockers. The user is questioning if switching to the more expensive Spectral.DNC-N is worthwhile compared to cheaper options like Kirkland minoxidil.
The user shared progress pictures after a year of treating hair loss with 5% minoxidil, then a combination of minoxidil/finasteride topical, and microneedling at 1.5mm bi-weekly. They plan to switch to oral finasteride and more frequent microneedling at a shallower depth while continuing the current regimen.
A new hair loss treatment, PP405, is moving from phase 2A to 2B in clinical trials, sparking discussions about its potential to regrow dormant hairs and its impact on existing treatments like Minoxidil and finasteride. Some users express skepticism, while others are hopeful about its future effectiveness.
PP405, a topical treatment, shows promise for hair growth by activating inactive follicles, with 66% of participants experiencing positive results. The treatment is well-tolerated and may proceed directly to Phase 3 trials, offering a potential alternative to minoxidil and finasteride.
The user has been using finasteride for 8 years and started using minoxidil foam 5% twice daily with micro-needling since May 2025. They experienced significant shedding starting in July and are seeking information on how long the shedding will last and when to expect positive results.
A human trial of verteporfin, a potential treatment for hair loss, with some users noting potential improvements in scarring and overall healing compared to control areas.
A 26-year-old male shared his hair loss treatment journey using finasteride, minoxidil, dutasteride, and microneedling, noting dissatisfaction with hair thickness but hoping for improvement. Users discussed side effects, treatment effectiveness, and shared personal experiences with similar treatments.
The user is two months into a hair loss treatment routine using Minoxidil 5%, microneedling with a 1.5mm needle once a week, Finasteride, and Biotin+collagen supplements, reporting thicker hair. Another user suggests microneedling is very effective, and a question is asked about the timing of Minoxidil application after microneedling.
The user has been using a hair loss treatment protocol including topical dutasteride, minoxidil with tretinoin, ketoconazole shampoo, microneedling, a laser cap, and vitamin D for 15 weeks, showing impressive progress. Feedback suggests continuing medical therapy for 12-24 months before considering a hair transplant.
RU58841 is being considered for hair maintenance by someone who can't tolerate finasteride. Alternatives like topical finasteride, dutasteride, and KX826 are also suggested.
User seeks treatment to increase minoxidil efficacy. Suggestions include microneedling, oral minoxidil, and Tretinoin, with mixed experiences and side effects.
The user shared progress pictures showing improvement in hair growth after one year of using finasteride and minoxidil. They are considering microneedling to further improve their hairline and have chosen to use a derma stamp.
Pelage is delaying the start of phase 3 trials for PP405 to 2026 due to necessary regulatory processes, despite having $120 million in funding. Users discuss the potential of PP405 for hair regrowth, with some expressing skepticism and others hopeful for new treatments like Breezula.
A 27-year-old male experienced rapid hair loss after dengue fever, which activated a balding gene. The doctor suggested platelet-rich plasma treatment for hair regrowth.
A female user is considering using RU58841 with minoxidil 2.5% to reduce side effects like facial hair from minoxidil 5%, while also using copper peptides and a hair serum. Other users discuss alternative treatments like spironolactone, alfatradiol, and the side effects of finasteride.
A user shared an extensive hair loss treatment regimen including dutasteride, minoxidil, tadalafil, RU58841, microneedling, and various topical and oral supplements. Responses varied, with some suggesting the regimen is excessive and others offering additional advice or expressing skepticism about its practicality and effectiveness.
The efficacy of microneedling for hair regrowth as either a stand-alone therapy or adjunct to Minoxidil, and whether Tretinoin is a safer and more effective option. Replies include personal accounts from users who have had success with microneedling in combination with minoxidil and peptide serums, as well as considerations of technique, depth, and potential scarring.
The user plans to enhance their hair loss treatment with oral minoxidil, finasteride tablets, laser cap therapy, and various supplements. They are also considering a hair transplant and exploring reputable sources for these products.
The user reported positive hair regrowth after 11 months on finasteride and 4 months of microneedling. Opinions in the conversation vary, with some endorsing microneedling as effective and others emphasizing finasteride as essential, while acknowledging that treatments may not work for everyone.
The conversation is about testing the effectiveness of RU58841 for hair loss, with the user planning to increase their dose to 30 mg per day along with 20 mg of Minoxidil. The test results showed approximately 70 mg/ml, which the user considers a good result.
The user is considering a hair regrowth routine using minoxidil, a laser cap, and possibly topical finasteride, while avoiding oral finasteride due to past surgery concerns. They plan to use these treatments for 6-8 months before consulting a hair transplant doctor.
A user is seeking advice on purchasing RU58841 from Biolab Shop in Poland and is looking for trustworthy sources that deliver to Germany from Europe or China. They are interested in the product's composition and user experiences.