Finasteride is discussed for hair loss treatment, with opinions divided on its safety and effectiveness. Some consider natural remedies, but these may also affect hormones.
The conversation is about determining which type of Saw Palmetto, either Chamaerops humilis or Serenoa repens, is effective for inhibiting the 5alphareductase enzyme related to hair loss. Specific treatments mentioned are Minoxidil, finasteride, and RU58841.
The conversation discusses whether topical finasteride, dutasteride, or antiandrogens like RU58841 can reduce sebum overproduction as an early indicator of their effectiveness in treating hair loss. It suggests that while hair growth may take months to observe, a decrease in oiliness could be a quicker sign of a product's action.
Finasteride can cause oily skin and acne due to increased testosterone or sensitivity of androgen receptors. Some users find dutasteride results in less oily skin compared to finasteride.
The conversation discusses the conflicting information about Zinc's effect on DHT and its role in hair loss. It mentions that Zinc can act as a 5AR inhibitor at high doses but may increase DHT if taken to correct a deficiency, and highlights the importance of nutritional balance for hair health.
The post discusses using a topical tincture containing zinc, azelaic acid, and other ingredients to inhibit 5alpha-reductase activity for treating hair loss. The user plans to try this natural alternative before using finasteride or RU58841.
Pumpkin Seed Oil and Perilla Oil (with alpha-lipoic acid, linoleic acid, and oleic acid) are discussed as potential 5alpha-reductase inhibitors. The conversation focuses on their effectiveness for hair loss treatment.
The post is a humorous take on the author's experience with hair loss and using finasteride for six months. The conversation includes discussions about hair loss, treatments like finasteride, and personal experiences with baldness.
17-alpha-estradiol may work for hair loss by inhibiting 5-alphareductase, similar to finasteride. It might lower testosterone in the scalp, reducing DHT conversion.
The conversation is about managing allopregnanolone deficiency caused by 5-alpha-reductase inhibitors like finasteride or dutasteride. Specific treatments discussed for hair loss include Minoxidil, finasteride, and RU58841.
The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5alphareductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.
A 19-year-old male has been using minoxidil 5% and dermarolling for four months to treat hair loss, applying minoxidil twice daily and dermarolling once a week. Commenters suggest consistent treatment, improving picture quality, and adding a 5-alpha-reductase inhibitor to enhance results.
The conversation discusses the use of 5-alpha-reductase inhibitors like finasteride and dutasteride for hair loss in transgender women, particularly in relation to testosterone suppression. The original poster has been using dutasteride and is considering stopping it due to undetectable testosterone levels.
Avixis Alfatradiol is a topical 5-alphareductase inhibitor available in Latin America and Germany, but its effectiveness is questioned. A user reported worsened hair loss after using it and recommended finasteride instead due to its proven effectiveness and lower cost.
Saw palmetto, a 5-alphareductase inhibitor, caused unexpected side effects like breast changes and altered semen consistency, which resolved after stopping its use. Concerns about similar side effects with finasteride or dutasteride were expressed, and another user reported low libido and depression from saw palmetto.
The conversation discusses the need for a localized 5-alphareductase inhibitor that only affects the scalp without systemic side effects, similar to pyrilutamide's approach. Current treatments like topical liposomal finasteride and dutasteride are mentioned, but concerns about their systemic effects and lack of research are highlighted.
Reishi mushroom is significantly weaker than finasteride for inhibiting 5alphareductase, requiring much larger quantities to achieve similar effects. The effectiveness and safety of consuming large amounts of Reishi for hair loss are uncertain.
The solution contains minoxidil, finasteride, azelaic acid, caffeine, retinoic acid, and procapil. Users suggest minoxidil with tretinoin and a 5-alphareductase inhibitor, while dismissing retinoic and azelaic acids as unnecessary.
It's safe to take oral dutasteride with pyrilutamide, as many use 5-alpha-reductase inhibitors with topical antiandrogens for better results. Avoid ingesting pyrilutamide.
The conversation is about considering pyrilutamide 1% as an alternative treatment for hair loss due to intolerance to 5-alphareductase inhibitors. Some users suggest it might be effective, while others view it as a temporary solution.
He Shou Wu (Fo Ti) extract was found to prolong the hair growth phase, inhibit 5-alpha-reductase (like finasteride), reduce androgen receptors, and increase growth factors, potentially outperforming minoxidil in recovering hair follicle size after DHT exposure. Two compounds, emodin and TSG, are identified as responsible for these effects and warrant further investigation.
A user asked if microneedling, massages, and essential oils can prevent further hair loss in the crown area without using drugs. The response indicated that without a 5-alpha-reductase inhibitor, hair loss will likely continue.
The conversation discusses a user's two-month hair regrowth progress using Minoxidil and a 0.5mm dermaroller. Some suggest adding a 5-alpha-reductase inhibitor like finasteride or dutasteride to maintain the results.
The impact of creatine on DHT levels, and whether it could cause accelerated male pattern baldness (MPB). The user taking a 5alphareductase inhibitor found that their DHT levels actually reduced despite taking creatine for nine weeks. Replies suggested looking into testosterone levels as well and debating the safety of creatine use in relation to MPB.
The conversation discusses alternative and unorthodox hair loss treatments, including RU58841, nandrolone, and dianabol, as well as theoretical approaches involving high doses of estrogen and selective estrogen receptor modulators. These methods are considered extreme and potentially harmful but are explored for those unable to tolerate traditional 5-alphareductase inhibitors.
A user shared a hair growth stack using minoxidil sulfate, valproic acid, bimatoprost, blue copper peptide, and other ingredients, emphasizing a gel-based formula for better skin tolerance. Another user suggested adding a 5-alpha-reductase inhibitor like finasteride or dutasteride for more effective long-term results.
User considers adding Alfatradiol to their topical finasteride treatment for hair loss. Others discuss Alfatradiol as a weak estrogen and 5α-reductase inhibitor used for pattern hair loss in men and women.
The user has been using topical minoxidil and finasteride since January and added topical dutasteride last month, seeing significant hair regrowth in five months. Other users shared their experiences with similar treatments, discussed side effects, and asked for details about the user's routine.
The conversation is about a user's hair regrowth after 2.5 months using topical minoxidil. Some suggest adding finasteride for long-term results, while others share their experiences with side effects or alternative treatments like dermarolling and dietary improvements.