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A user's plan to use Zix and topical finasteride (5AR inhibitors) for hair loss, followed by blood testing before/after. The user has suggested creating a fund to cover part of the cost of their blood tests. Replies to their post discuss the effectiveness of the treatments.

Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

The user has been using 5% minoxidil and finasteride for a year and recently noticed three new hairs, but other baby hairs aren't growing. They are considering switching to only minoxidil.

People using minoxidil and finasteride often see hair regrowth results around 4-5 months, but some experience no progress even after 10 months. Switching to dutasteride or adjusting dosages can lead to improvements, with some users noticing changes as early as 3 months.

The user reported tiny hair growth in thinning areas and improved thickness after 56 days of using 1 mg oral finasteride, 2.5 mg oral minoxidil, and a serum with Redensyl, Anagain, Capixyl, and Procapil. They also take supplements and maintain a healthy lifestyle with no noticeable side effects.

An 18-year-old experienced hair regrowth using 5% liquid minoxidil and plans to start finasteride at 19. The user noticed thicker hair and new growth, particularly around the temples, and feels more confident.

The user experienced hair regrowth using topical finasteride 0.1%, minoxidil 10%, and microneedling over a year, recovering about 5 years of hairline and 3 years of density. The treatment was applied to the temples and frontal area, with some recovery in the coronal area attributed to microneedling.

The user started finasteride and oral minoxidil for early-stage hair loss around the crown and underwent a session of exosome treatment 3.5 months ago. They are seeing some improvements and are questioning the effectiveness of exosomes for hair regrowth.

The user has been taking 0.5 finasteride for 10 months and wants to repeat blood tests, including estradiol. However, their doctor is reluctant to test estradiol, arguing it's typically low in men, and the user is considering seeking a second opinion.

GLA may help with hair loss due to its anti-inflammatory properties and 5ar enzyme inhibition. It's considered potentially more important than biotin, especially for those already using finasteride and dutasteride.

The post and conversation are about HMI-115, a potential treatment for hair loss. The conclusion is that HMI-115 is not a 5ar-inhibitor and is instead a prolactin receptor inhibitor. Some users are skeptical about its effectiveness and believe that baldness will still be a problem in the future.

OP uses a hair loss treatment stack including dermastamp, Minoxidil 5%, Alfatradiol 0.2%, Pyrilutamide 0.9%, and Nizoral shampoo, costing around 100-110€ monthly. OP avoids finasteride due to past negative experiences.

The user shared their 1-year progress using 2.5 mg oral minoxidil and 0.5 mg oral dutasteride for hair loss, noting visible improvement despite initial shedding. They observed results around the 5-month mark and received positive feedback from others.

The user has been using topical 5% Minoxidil, 0.1% Finasteride, dermastamping, 2% ketoconazole, and a DHT-blocking shampoo with saw palmetto, caffeine, biotin, and argan oil for hair loss. Despite some baby hair growth on one side, the user is experiencing continued hairline recession and shedding, leading to distress.

The user shared their experience with hair regrowth using a natural approach, including a good diet, multivitamins, pumpkin seed oil, and scalp massages, without using minoxidil or finasteride. They emphasize this method for those with stabilized hair loss around Norwood 1.5 - 2, noting satisfactory progress over a year.

The user shared their one-year progress using 5% topical minoxidil and 1mg oral finasteride, reporting good results with some shedding phases. They experienced no side effects and noted improved hair density, especially in the frontal area.

The conversation is about a person's hair improvement after 14.5 months using RU58841 and Minoxidil topically at 50 mg each day, with noticeable hairline improvement but incomplete crown area recovery. The person struggles to take good pictures of their crown area.

Kintor Pharmaceutical's Phase 2 results with the drug Pyrilutamide, a potential alternative to 5-ARI drugs like Finasteride and Dutasteride but without the side effects. It could be used in combination with other topical treatments such as Minoxidil. The safety of the drug has been demonstrated in 6 months of use, however there are still questions about long term efficacy and systemic absorption.

The user shared their 11-month hair regrowth journey using 0.83mg finasteride, Minoxidil twice daily, random derma rolling, and occasional Ketoconazole showers. They reported significant improvement, moving from a Norwood scale of 5.5 to around 2.5-3, and encouraged consistency for results.

A 40-year-old male has been using 5% minoxidil foam twice daily, 1mg finasteride, and a weekly derma roller for 2.5 months to address hair loss. It's suggested to stay consistent, as noticeable changes typically occur around 8 months.

A 28-year-old male experienced significant hair regrowth using dutasteride 0.5 mg and 2.5 mg oral minoxidil after previous treatments with minoxidil and finasteride became less effective. He reported no major side effects, except for unwanted hair growth in certain areas.

A 26-year-old male started treatment with 1 mg finasteride and 2.5 mg oral minoxidil on September 25. By November, he noticed significant hair regrowth with no major side effects, except increased hair growth in other areas.

A 31-year-old experienced hair regrowth using a daily regimen of 5% minoxidil spray and 1mg oral finasteride over six months, with no side effects. The user noticed slow but positive progress, especially in the temple area, and plans to continue the treatment as advised by their doctor.

The user shared their 4-month progress using a topical solution of 5% minoxidil and 0.1% finasteride, reporting initial shedding that stopped after 2.5 months and noticeable regrowth, especially in the crown area. They use Glenmark Hair4U F from India and have experienced no side effects.

A user asked if microneedling, massages, and essential oils can prevent further hair loss in the crown area without using drugs. The response indicated that without a 5-alpha-reductase inhibitor, hair loss will likely continue.

The user is happy with their 6-month hair transplant progress of 4600 grafts in Turkey and has been using finasteride for 5 years and minoxidil for 4 years. The donor area is in good condition, potentially allowing for future hair reinforcement.

User shared results of using minoxidil and dermaneedling for hair loss over 2.5 months, noting improvements, especially around the left temple. No finasteride or other anti-androgens were used.

Latanoprost is discussed as a potential hair loss treatment, noted for its synergy with minoxidil and 5-AR inhibitors, but concerns include its effectiveness on scalp hair, cost, and potential skin darkening. Some users express interest in trying latanoprost or bimatoprost despite limited real-world evidence.

How Finasteride and Dutasteride help reduce hair loss by reducing the amount of DHT in scalp areas, as well as discussing factors such as sensitivity to DHT, 5α-reductase expression in different parts of the hair follicle, and scalp tension.

Finasteride was intentionally developed to treat BPH and later approved for male pattern baldness (MPB) due to its 5AR inhibition effects. The delay in MPB approval was due to concerns about off-label use for female hirsutism and the prioritization of treating a more debilitating condition.