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      community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

      in Research/Science  63 upvotes 2 years ago
      Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

      community Diffuse thinning chronicles pt. 2

      in Progress Pictures  16 upvotes 2 years ago
      A 27-year-old Asian male is treating hair loss with 1mg oral finasteride, topical minoxidil twice daily, and 1.5mm microneedling weekly. The discussion is about his progress with these treatments.

      community Minoxidl 5% and finasteride 1.25mg daily 11 months

      in Finasteride/Dutasteride  101 upvotes 10 months ago
      The conversation discusses using minoxidil 5% and finasteride 1.25mg daily for hair loss, with the user experiencing monthly shedding and a slight decrease in sex drive as a side effect. The user also mentions using a shampoo with piroctone olamine for seborrheic dermatitis and considers oral minoxidil to reduce scalp irritation.

      community How to reduce scalp DHT as much as possible?

      in Finasteride/Dutasteride  16 upvotes 8 months ago
      The conversation discusses reducing scalp DHT to prevent hair loss, with a focus on using dutasteride, finasteride, and other treatments like RU58841 and minoxidil. It highlights the challenges of managing hair loss while on high testosterone levels, suggesting that dutasteride may be more effective than finasteride in such cases.

      community Minoxidil: Sulfotransferase Enzyme booster AVAILABLE NOW

      in Minoxidil  7 upvotes 2 years ago
      A new product, Minoxidil booster, which enhances sulfotransferase enzyme activity in the scalp, is now available. The user has started using this product, applied before Minoxidil, to improve their hair loss treatment results.

      community 35M Just min 5%/Biotine 5000mcg 6 month.

      in Progress Pictures  22 upvotes 10 months ago
      A 35-year-old man used minoxidil 5% and biotin 5000 mcg for six months, resulting in significant hair regrowth. He experienced initial shedding but avoided finasteride due to potential side effects.

      community 5 month Progress (18m)

      in Progress Pictures  33 upvotes 5 years ago
      An 18-year-old shares a 5-month hair loss treatment progress using finasteride, minoxidil, microneedling, Nizoral, biotin, and fish oil. The user discusses the effectiveness of finasteride over time and considers continuing the regimen despite suggestions to simplify it.

      community Guys, we finally have an alternative to finasteride

      in Research/Science  263 upvotes 1 year ago
      A combination of pyrilutamide, minoxidil, and alfatradiol is proposed as an effective alternative to finasteride for treating mild to moderate hair loss, claiming to stabilize hair loss and improve thickness without finasteride's side effects. Some users are skeptical about the effectiveness and approval of these treatments, while others are interested in trying them due to finasteride's side effects.

      community GT20029 and PP405 the new fin and min that we been waiting for ?

      in Chat  36 upvotes 1 year ago
      PP405 and GT20029 are new hair loss treatments with different mechanisms from traditional options like Minoxidil and Finasteride. PP405 targets hair follicle stem cells to reactivate growth, while GT20029 works as an androgen receptor deleter, both requiring ongoing use for effectiveness.

      community Experience with Redensyl?

      in Product  8 upvotes 6 years ago
      Hair loss treatments, specifically experiences with Redensyl as well as other treatments such as Minoxidil, finasteride and RU58841.

      community 5 months Finasteride (.5mg) and Minoxidil (2.5mg)

      in Progress Pictures  223 upvotes 6 months ago
      The user experienced significant hair regrowth and improved hair health after 5 months of using 0.5mg finasteride and 2.5mg minoxidil daily, with only minor side effects like reduced libido. The user is optimistic about achieving over 90% regrowth and may not need a hair transplant.

      community Oral 5mg minoxidil and 1mg finastride

      in Product  4 upvotes 1 year ago
      The conversation is about using 5mg oral minoxidil, 1mg oral finasteride, and Keto shampoo for hair loss, with additional supplements like Biotin, multivitamins, and Vitamin D3 with K2. Suggestions include possibly switching to 2.5mg dutasteride instead of finasteride.

      community Today was Last update on pp405

      in Research/Science  109 upvotes 11 months ago
      A new hair loss treatment, PP405, is moving from phase 2A to 2B in clinical trials, sparking discussions about its potential to regrow dormant hairs and its impact on existing treatments like Minoxidil and finasteride. Some users express skepticism, while others are hopeful about its future effectiveness.

      community [2 months progress] 1mg oral fin + 2.5mg oral min daily

      in Progress Pictures  7 upvotes 2 months ago
      The user reported tiny hair growth in thinning areas and improved thickness after 56 days of using 1 mg oral finasteride, 2.5 mg oral minoxidil, and a serum with Redensyl, Anagain, Capixyl, and Procapil. They also take supplements and maintain a healthy lifestyle with no noticeable side effects.

      community Anyone used Topical Calcipotriol (cream) or VPA ( Valproic Acid)

      in Chat  9 upvotes 5 years ago
      The conversation discusses using topical Calcipotriol and Valproic Acid for hair loss, focusing on their mechanisms involving the VDR receptor and Wnt/beta-catenin pathway. Specific treatments mentioned are Minoxidil, Finasteride, and RU58841.

      community Targeting multiple AGA mechanisms with commonly available substances

       4 upvotes 7 years ago
      The conversation discusses using a multimodal approach to treat androgenic alopecia, including substances like gamma-linolenic acid, DHA, sulforaphane, melatonin, cetirizine, astaxanthin, fisetin, apigenin, curcumin, limonene, genistein, and berberine. Users also mention using ketoconazole, minoxidil, and low-level laser therapy (LLLT) as part of their hair loss treatment regimens.

      community 2nd Edit: 33m. One year on 5%Min + 0.5% Tret

      in Progress Pictures  52 upvotes 2 months ago
      A 33-year-old man shares his one-year progress using 5% Minoxidil and 0.5% Tretinoin cream, along with derma stamping and specific shampoos, to combat hair thinning and promote hair growth. He avoids using finasteride or dutasteride, despite suggestions from others to try them for long-term maintenance.

      community 35% regrowth brothers and sisters! More effective than Minox and Fin?

      in Treatment  107 upvotes 7 years ago
      A double-blind clinical study that found ingestion of tocotrienols resulted in a 34.5% increase in hair regrowth compared to the placebo group, and discussion about potential side effects and cost of supplementation with vitamin E pills. The conversation noted that it may be more effective than commonly used treatments like minoxidil and finasteride.

      community Overwhelming amount of anti-androgens

      in Female 3 years ago
      The conversation discusses the effectiveness of anti-androgens for hair loss, with a preference for topical treatments like RU58841 over oral options due to better scalp concentration and fewer side effects. Topical finasteride at 0.1% may provide some results, especially when combined with a topical androgen receptor antagonist like RU58841.

      community Oral Minoxidil - The Hyper-Responder Concept

      in Research/Science  5 upvotes 7 months ago
      Minoxidil's effectiveness varies due to genetic differences in the SULT1A1 enzyme, affecting how well it converts to its active form, minoxidil sulfate. Hyper-responders may experience rapid hair growth and increased side effects, such as pericardial effusion, even at low doses.