Search
for

    Sort by

    Community Join

    270-300 / 1000+ results

      community If dutesteride and oral minoxidil doesn’t work that’s it right?

      in Treatment  20 upvotes 2 years ago
      A user is experiencing continued hair loss despite using 0.5mg dutasteride and 2.5mg minoxidil, and is seeking advice on why the treatments aren't working and how to address potential androgen receptor sensitivity. Replies suggest getting tested and considering scalp micropigmentation (SMP).

      community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.

      in Research/Science  3 upvotes 1 year ago
      DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.

      community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

      in Research/Science  93 upvotes 4 years ago
      The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.

      community AA and Hirsutism but T levels are normal

      in Female  5 upvotes 5 years ago
      27-year-old female experiences aggressive hair thinning and hirsutism despite normal testosterone levels. Spironolactone and 2% minoxidil were ineffective; high DHEA sulfate levels may be the cause.

      community Nizoral ketaconazole any good for dht reduction

      in Ketoconazole  8 upvotes 5 years ago
      A 17-year-old is looking for alternatives to finasteride for DHT control to preserve hair, considering ketoconazole shampoo for its potential to inhibit 5AR and also thinking about using caffeine-containing shampoos like alpecin or watermans.

      community High DHT with finasteride. Help!

      in Finasteride/Dutasteride  6 upvotes 2 years ago
      Despite using 5% minoxidil, 0.1% finasteride, and other treatments like microneedling, MK-677, and Cialis, hair loss continues with high testosterone and DHT levels. Considering oral dutasteride but concerned about further increasing testosterone levels.

      community Why is no one talking about redensyl?

      in Question  56 upvotes 6 years ago
      Exploring the effectiveness of redensyl, a hair loss treatment, compared to minoxidil and finasteride. People shared experiences using redensyl and products containing it, such as The Ordinary Hair Serum.

      community Creatine and ru-58841 experiences?

      in Chat  1 upvotes 9 months ago
      RU58841 is preferred over finasteride for blocking DHT on the scalp, especially for those with aggressive MPB. Creatine is associated with increased hair shedding, even when using RU58841.

      community Any experience with dutasteride 2.5mg dose? (Or any dose more than 0.5 mg).

      in Finasteride/Dutasteride  2 upvotes 5 months ago
      A user with aggressive androgenic alopecia is considering increasing their dutasteride dose from 0.5 mg to potentially 2.5 mg, while already using oral minoxidil, Nizoral, RU-58841, and dermapen. They are seeking advice on the effectiveness and side effects of higher dutasteride doses, with suggestions to consult a dermatologist and consider a higher Nizoral concentration.
      Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI?

      community Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI?

      in Treatments  451 upvotes 1 year ago
      Topical dutasteride is suggested as a low side-effect treatment for hair loss, with a proposed dose of 0.025% 1ml/day. It is considered better than finasteride due to its even inhibition of DHT isoforms and lower systemic absorption.

      community Ru-58841 vs KX-826/pyrilutamide while on steroids

      in Finasteride/Dutasteride  5 upvotes 1 year ago
      The user increased their steroid dosage and noticed hair shedding, so they adjusted their regimen by reducing steroid doses and adding oral dutasteride. They are also experimenting with combining RU-58841 and KX-826/pyrilutamide in minoxidil to address hair loss.

      community Minoxidil is a 5ar inhibitor according to research

      in Research/Science  148 upvotes 8 months ago
      Minoxidil may inhibit androgen receptors and affect hormonal pathways, potentially explaining its effectiveness in treating androgenetic alopecia (AGA). Users discuss its varying effectiveness on scalp versus facial hair and note fewer side effects with topical use compared to oral.

      community Some among us are the chosen ones

      in Chat  122 upvotes 11 months ago
      Some individuals experience hair loss despite using treatments like 2.5 mg dutasteride, finasteride, and minoxidil, suggesting sensitivity to DHT or other factors. Various treatments and lifestyle changes are discussed, but results vary, and some consider hair transplants or other solutions.

      community Oral Minoxidil - The Hyper-Responder Concept

      in Research/Science  5 upvotes 7 months ago
      Minoxidil's effectiveness varies due to genetic differences in the SULT1A1 enzyme, affecting how well it converts to its active form, minoxidil sulfate. Hyper-responders may experience rapid hair growth and increased side effects, such as pericardial effusion, even at low doses.

      community Why are low finasteride doses seen as highly ineffective, when studies show 0.05 mg/day to work?

      in Finasteride/Dutasteride  38 upvotes 3 years ago
      The efficacy of low doses of finasteride to reduce scalp DHT, and whether studies showing a 61% reduction are reflected in actual results. Replies discussed hair growth as an unintended consequence of minoxidil and finasteride use, as well as self-selective bias, potential side effects, and that studies measure effectiveness by hair count changes rather than DHT inhibition.

      community Testosterone and Estradiol levels on 1 mg/day dutasteride

      in Finasteride/Dutasteride  43 upvotes 8 months ago
      A 30-year-old man experienced significant hair regrowth and improved libido after using finasteride and dutasteride for androgenetic alopecia, with no adverse effects. He plans to reduce dutasteride dosage when trying to conceive and has been using topical minoxidil since 2015.

      community Minoxidil works amazingly, you just need to give it time.

      in Minoxidil  326 upvotes 6 months ago
      Minoxidil can effectively promote hair regrowth with consistent use, but results differ among individuals. Some recommend combining it with finasteride for better long-term results, though OP chooses to use only minoxidil and accepts the possibility of going bald.

      community Loosing ground, on fin and min. 4years progression

      in Update  191 upvotes 1 year ago
      The user has been using finasteride and minoxidil for hair loss since 2021, with some initial regrowth but now considering switching to dutasteride due to concerns about further hair loss. They also use microneedling and are exploring tretinoin, while others suggest adding oral minoxidil or a hair transplant for better results.

      community Almost 4 months of oral fin, topical min and microneedling

      in Progress Pictures  752 upvotes 2 years ago
      User "Mostuls" shared their 4-month hair loss treatment routine, which includes daily oral finasteride, twice-daily topical minoxidil, and microneedling twice a week with no side effects. Other users discussed the specifics of the treatment and expressed positive reactions to the results.

      community Lowest Effective RU58841 Dose?

      in Treatment  4 upvotes 1 year ago
      RU58841 is discussed as a hair loss treatment, with users considering lower doses like 2.5% to reduce costs. Some users suggest that if already blocking DHT, lower doses might still be effective unless there's high sensitivity to DHT.