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      community RU58841, 8% HPLC-MS done by jano, they legit

      in Research/Science  7 upvotes 4 years ago
      The conversation is about testing the effectiveness of RU58841 for hair loss, with the user planning to increase their dose to 30 mg per day along with 20 mg of Minoxidil. The test results showed approximately 70 mg/ml, which the user considers a good result.
      [M23] Finasteride journal

      community [M23] Finasteride journal

      in Journals / Progress Pictures  92 upvotes 11 months ago
      A 23-year-old male noticed hair loss and started using finasteride 1mg, initially experiencing significant shedding which reduced after 100 days. He switched from the brand Andropel to Folcres due to availability in Argentina.

      community Very high testosterone and estradiol on finasterid 1 mg. Am I cooked?

      in Finasteride/Dutasteride  3 upvotes 4 months ago
      A 29-year-old male on 1 mg Finasteride for 3 months has experienced a significant increase in testosterone and estradiol levels, with no major side effects except slightly oilier skin and increased emotional sensitivity. The user is concerned about these hormonal changes and seeks advice, as their general practitioner is not knowledgeable about the issue.

      community Only 1.5 months into treatment - is this normal or too fast?

      in Progress Pictures  16 upvotes 3 months ago
      A 21-year-old started treatment for androgenetic alopecia and seborrheic dermatitis with oral finasteride, topical minoxidil, anti-dandruff shampoo, and a corticosteroid solution. After 1.5 months, they noticed increased hair density and are considering switching to oral minoxidil due to scalp issues.

      community My personal thoughts on DHT. belive it or not

      in Research/Science 1 year ago
      The conversation discusses a personal theory on the role of DHT in stress and reproduction, suggesting it converts testosterone for reproductive traits. The discussion includes skepticism and mentions individual differences in physiology and neurochemistry.

      community Got some bloodwork done, horrifying results.

       10 upvotes 8 years ago
      The user is concerned about high DHT levels despite using finasteride and dutasteride for hair loss, suggesting these treatments may not be effective. They plan to consult an endocrinologist and consider other antiandrogens, acknowledging potential side effects.

      community M19 shed after 1yr on dutasteride

      in Finasteride/Dutasteride  23 upvotes 1 year ago
      A 19-year-old male experienced hair shedding after one year on dutasteride and is considering adding topical minoxidil despite scalp itching. Users suggest continuing dutasteride, maintaining a consistent hair routine, and possibly increasing minoxidil dosage.

      community EMA is re-examining Winlevi (clascoterone at lower concentration)

      in Treatment  9 upvotes 9 months ago
      Clascoterone in Winlevi, a topical AR antagonist, is being re-examined due to concerns about HPA axis suppression in adolescents, but it's unlikely to be banned for adult use in androgenetic alopecia (AGA). The European Medicines Agency recommended refusing Winlevi for acne vulgaris, but this may not affect Breezula's approval for AGA.

      community Thanks bruh, I appreciate yall

      in Progress Pictures  65 upvotes 10 months ago
      The user experienced hair growth improvement using a 1.25mm microneedle weekly, oral finasteride, oral minoxidil, and rosemary oil. They plan to switch to generic finasteride and minoxidil for safety concerns.

      community KX-826 1% Phase II Results from China Just Dropped

      in Research/Science  36 upvotes 8 months ago
      KX-826 (Pyrilutamide) 0.5% and 1.0% solutions showed promising results in increasing hair count for male androgenetic alopecia, with the 0.5% dose slightly outperforming the 1% dose. The treatment was well-tolerated with no sexual side effects, but skepticism remains due to past inconsistencies in trial results.

      community Finasteride and male phenotypes

       5 upvotes 10 years ago
      Finasteride's effectiveness and side effects may vary based on male phenotypes, with some users noting differences in response related to body and facial hair characteristics. Some users report success with lower doses, while others experience side effects, suggesting individual variability in response to the treatment.

      community Shaved at 21, time for me to move on after very little improvement from meds.

      in Shaved/buzzed  54 upvotes 2 years ago
      The user has been experiencing hair loss since the age of 16 and has tried various treatments including minoxidil, finasteride, RU58841, microneedling, and keto 2%. Despite these efforts, there has been little improvement in hair growth. The user is considering other options such as dutasteride, perilutimide, or a hair transplant in the future, but for now, they are accepting the shaved look and focusing on personal growth and school.

      community A Technical Question About Pyrilutamide

      in Research/Science  5 upvotes 2 years ago
      Pyrilutamide is believed to be more effective than RU58841 and 1 mg finasteride in treating hair loss, with no systemic hormonal effects and the potential to block more than 31% of scalp DHT. It may also antagonize scalp testosterone due to its action as an androgen receptor antagonist.

      community NW5.5 testing stack of most common "alternative" treatments and methods

      in Progress Pictures  2 upvotes 1 week ago
      A 43-year-old male with advanced hair loss is experimenting with alternative treatments, including red light therapy, microneedling, scalp massages, an oil mix, and ketoconazole shampoo, after previously experiencing side effects from finasteride and minoxidil. He noticed some minor changes with red light therapy but remains skeptical about significant improvement.

      community [2 months progress] 1mg oral fin + 2.5mg oral min daily

      in Progress Pictures  6 upvotes 5 days ago
      The user reported tiny hair growth in thinning areas and improved thickness after 56 days of using 1 mg oral finasteride, 2.5 mg oral minoxidil, and a serum with Redensyl, Anagain, Capixyl, and Procapil. They also take supplements and maintain a healthy lifestyle with no noticeable side effects.

      community important questions about RU58841

      in Research/Science  3 upvotes 2 years ago
      The user has been using finasteride for hair loss and is considering adding RU58841. They ask about RU58841's effectiveness, potential heart side effects, duration of action, dosage increase over time, transitioning to GT20029, and where to find the liquid form.
      PP405 Identity Research

      community PP405 Identity Research

      in Research  292 upvotes 7 months ago
      PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.