The user is experiencing increased hair shedding after one year of using oral dutasteride. They are seeking opinions on their DHT test results, which show levels below baseline.
Blocking DHT is not a cure for hair loss; instead, altering how scalp follicles respond to DHT might be more effective. Current treatments like topical finasteride and minoxidil are temporary solutions, and future approaches may involve gene therapy and bioengineering to change follicle behavior.
User discusses group buy for finerenone, a third-gen mineralocorticoid antagonist for hair loss treatment. Finerenone inhibits TGFb, NOX, and ROS, and improves renal and cardiac function; topical dose should be no more than 10mg per day.
A 24-year-old shared his 11-month hair regrowth progress using 1mg oral finasteride, Dr. Reddy's Minoxidil + Finasteride 5% topical solution, 2.5 mg oral minoxidil, microneedling, ketoconazole shampoo, and plans to switch to dutasteride and tretinoin. Users praised his progress, discussed hair regrowth strategies, and shared personal experiences with hair loss treatments.
Minoxidil may not be effective due to low sulfotransferase activity, and the user considers adding tretinoin to the regimen. They are unsure about the timing and combination with microneedling.
New hair loss treatments PP405 and VDPHL01 are discussed with skepticism and hope, alongside existing treatments like minoxidil and finasteride. Users express frustration over limited progress since the 1980s but remain cautiously optimistic.
The user experienced increased hair shedding after switching from finasteride to dutasteride, despite lifestyle improvements and additional treatments like oral minoxidil and PRP. They are concerned about persistent shedding, changes in hormone levels, and potential chronic telogen effluvium, and are considering a scalp biopsy for further investigation.
A user shared progress pictures showing significant hair regrowth after using a topical solution containing 5% Minoxidil, Finasteride, Redensyl, and Procapyl. The user reported no side effects and applies the solution twice daily.
The conversation discusses the safety and effectiveness of a hair loss drug, GT20029, and the possibility of infrequent application, with users hoping for once-daily use and speculating on the drug's duration of effect on the scalp. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.
Rhamnose may promote hair growth and pigmentation, suggesting it as a potential hair loss treatment. The conversation discusses its potential alongside known treatments like Minoxidil, finasteride, and RU58841.
A 20-year-old male currently using topical minoxidil 5% is considering starting finasteride 1mg due to elevated hormone levels. He seeks advice on whether to adjust anything before beginning finasteride.
A user shared progress pictures showing significant hair regrowth after using 1mg finasteride and weekly microneedling for about 2.5 to 3 months. The user reported no side effects and maintained good health and mood.
A person shares their 10-month hair loss treatment progress using finasteride 1.25 mg daily, topical minoxidil 5% daily, weekly dermarolling with a 1.5mm device, and RU58841 for one month, encouraging others not to give up despite slow results. They noticed their progress after comparing past photos.
The user reported significant hair regrowth using a topical treatment of 0.3% finasteride and 6% minoxidil, with noticeable progress in five months. The treatment is applied once daily, and the user experienced some initial shedding but no side effects.
A 21-year-old male experienced negative side effects from oral finasteride and is considering switching to topical finasteride or RU58841 after using oral minoxidil. He seeks advice on a standard hair loss routine, mentioning peptides, RU58841, and dermarolling.
PP405 might make minoxidil unnecessary, but finasteride or other 5AR inhibitors may still be needed. PP405 is expected to be expensive and not available until at least 2028, with limited information on its effectiveness.
Using high doses of testosterone with RU58841 to create an androgen-free environment for hair regrowth is suggested, but concerns about heart health and the effectiveness of this approach are raised. Alternatives like topical estrogen, progesterone, and other treatments like finasteride and dutasteride are discussed.
Take 1mg finasteride daily as the standard approach; adjust only if side effects occur. Many users experiment unnecessarily with doses and methods, complicating treatment.
A 25-year-old male is using topical minoxidil and plans to start finasteride and a keratin supplement to combat hair loss. He will document his progress with photos and track any side effects.
A 24-year-old has been using Minoxidil and finasteride for 1.5 years with mild improvement but is being rejected for hair transplants due to age and diffuse thinning. They are seeking advice on what to do next.
A 33-year-old man shares his one-year progress using 5% Minoxidil and 0.5% Tretinoin cream, along with derma stamping and specific shampoos, to combat hair thinning and promote hair growth. He avoids using finasteride or dutasteride, despite suggestions from others to try them for long-term maintenance.
The conversation discusses hair loss treatments, specifically the use of 5% topical minoxidil, with considerations for adding finasteride or dutasteride. Concerns about side effects, such as unwanted body hair growth from oral minoxidil, are also mentioned.
The user has been using finasteride and dutasteride for hair loss but is experiencing low energy and motivation, possibly due to high prolactin levels. Despite treatment, hairline recession continues, and the user is considering the impact of low DHT levels on overall health and energy.
A 29-year-old male experiencing hair loss due to TRT is using minoxidil and dermarolling but is hesitant to use finasteride or dutasteride due to potential side effects. He is considering low level laser therapy (LLLT), PRP, ketoconazole shampoo, and oral minoxidil as additional treatments. A reply suggests that without a DHT blocker like finasteride or dutasteride, other treatments may not be effective long-term.
The conversation discusses the lack of clinical studies on cysteine alone for hair loss, with the original poster already using medications like Minoxidil and finasteride. Suggestions include trying 2ddr as a growth stimulant, though concerns about side effects like gas are mentioned.
A 30-year-old male switched from finasteride to a combination of dutasteride, oral minoxidil, and RU58841, achieving significant hair growth without side effects. He plans to add GHK-Cu peptide to his regimen for further improvement.
A 23-year-old male experienced good hair growth and increased self-confidence after 10 months of using oral finasteride (1.25mg) and topical minoxidil (5% twice a day), despite no decrease in hair shedding. He also used 1mm microneedling monthly and reported minor side effects like forgetfulness.
Azelaic acid is discussed as a DHT inhibitor with no reported sexual side effects, but its effectiveness and absorption as a topical treatment are questioned. The user is interested in azelaic acid due to concerns about finasteride affecting penile health.