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      community DHEA, the culprit behind DUPA ? Read this!

      in Research/Science  19 upvotes 2 years ago
      High DHEA levels may contribute to hair loss by increasing DHT in hair follicles, potentially explaining why finasteride is ineffective for some. Treatments like high-dose dutasteride and RU58841 are suggested, but the underlying cause, such as adrenal issues, should be investigated.

      community Finasteride 1.25mg 10 month Progress

      in Progress Pictures  151 upvotes 2 years ago
      The user shared a 10-month hair loss treatment routine using Finasteride, ketoconazole shampoo, and Red Light Therapy, noting significant progress and considering adding Dutasteride. They experienced initial side effects and changes in libido, but overall reduced hair shedding and regrowth, especially at the temples.

      community Finasteride shed at 5.5 months? - dose increase 4 weeks ago

      in General  107 upvotes 11 months ago
      The user is experiencing hair thinning after increasing finasteride to 0.5 mg daily and oral minoxidil to 3 mg. They are concerned about whether this is normal and if the recent dose increase is affecting their hair, as they plan a hair transplant in 5 weeks.

      community DHT is about to get smashed ….

      in Update  801 upvotes 1 year ago
      The conversation discusses hair loss treatments like topical finasteride with minoxidil, oral dutasteride, and essential oils. Oral treatments like dutasteride and finasteride are seen as more effective, though some prefer topicals to avoid side effects.

      community He is claiming, he can treat alopecia

      in Chat  357 upvotes 5 months ago
      A user claims a product can treat alopecia, but others are skeptical, calling it a scam due to lack of evidence and transparency. The product is said to inhibit Type II 5-αr by 22.9%, but is considered weaker than existing DHT blockers.

      community hight pre-finasteride estrogen levels

      in Finasteride/Dutasteride  1 upvotes 2 years ago
      A user with high pre-finasteride estrogen levels is asking if they need to normalize their hormone levels before starting finasteride and whether they should postpone dermarolling until they begin finasteride. The user is 21.5 years old.

      community Additional supplements / peptides to maximize finasteride benefit

      in Research/Science  3 upvotes 3 weeks ago
      The user is using finasteride, HGH, GHK-CU, BPC-157, KPV, biotin/collagen/keratin vitamins, ketoconazole shampoo, and low-dose naltrexone to address hair loss, avoiding minoxidil due to past shedding experiences. Adenosine is discussed as a potential alternative to minoxidil, though it is noted to be expensive and hard to find.

      community Is PP405 gonna flop or what???

      in Research/Science 2 months ago
      PP405 is viewed skeptically, with some seeing it as overhyped and potentially ineffective compared to existing treatments like minoxidil and finasteride. While it shows some promise in activating dormant hair follicles, many believe it won't replace hair transplants or significantly outperform current options.

      community Is 2.5 mg dut really more effective than .5?

      in Finasteride/Dutasteride  10 upvotes 2 years ago
      A user on .5 mg of dutasteride for hair loss saw no improvement and is considering increasing to 2.5 mg but is unsure of its effectiveness. Another user mentioned that 2.5 mg reduces scalp DHT more and increases hair count more than .5 mg, but the cost and side effects should be considered.

      community 2.5 years 1mg finasteride daily

      in Progress Pictures  4864 upvotes 4 months ago
      Significant hair regrowth was achieved after 2.5 years of taking 1 mg finasteride daily, without using minoxidil or microneedling. Minor side effects included a slightly thinner beard and longer time to finish during sex.

      community Hot Take: Betting on PP405 can backfire

      in Research/Science  81 upvotes 11 months ago
      PP405 is seen as promising but uncertain, with users advised to continue using existing treatments like minoxidil and finasteride. Concerns include its cost, availability, and interaction with hair transplants, while some hope it could complement current treatments.

      community 5 Months Minoxidil (and ~1.5 Years Fin/Dut)

      in Progress Pictures  594 upvotes 1 year ago
      The user experienced significant hair regrowth after switching from finasteride to dutasteride and from topical to oral minoxidil, despite some patchiness along the hairline. The user reduced the oral minoxidil dose due to low blood pressure concerns.

      community My home made topical dutasteride

      in Finasteride/Dutasteride  3 upvotes 1 year ago
      The conversation is about a user making a homemade topical dutasteride solution to use alongside testosterone replacement therapy (TRT) and oral dutasteride. The user aims to reduce DHT locally at the testosterone injection site and on the scalp.

      community DHT before and after from .5mg DUT once a week

      in Research/Science  29 upvotes 7 months ago
      The user experienced improved libido and erections after reducing DHT levels with 0.5mg of dutasteride once a week, despite previous side effects from finasteride. They are also on testosterone replacement therapy and have not noticed major personality changes.

      community blood DHT levels shot up after doubling dutasteride dosage

      in Finasteride/Dutasteride  20 upvotes 2 years ago
      A user increased their dutasteride dosage from 0.5mg to 1mg daily, resulting in a rise in DHT levels from 148 pg/mL to 281 pg/mL, and is considering switching back to finasteride due to continued hair loss. Replies suggest retesting and emphasize the importance of bloodwork before starting treatments.

      community 1.5 Years Before and After. Fin Oral and Topical

      in Progress Pictures  92 upvotes 1 year ago
      The conversation is about a user's progress with hair loss treatment using 0.5mg oral finasteride and 50ml of Essegen-F topical finasteride daily, with improved hair density and minimal side effects. The user also used ketoconazole shampoo for seborrheic dermatitis and noticed significant hair regrowth over 1.5 years.

      community [43M] 6 months topical .01%->.025% / 5% min

      in Progress Pictures  7 upvotes 1 year ago
      A 43-year-old man shares his slow progress using low-dose topical finasteride and 5% minoxidil for hair growth, along with scalp massages, microneedling, biotin supplements, and pumpkin seed oil. Another user suggests shaving and warns about potential infertility from finasteride, but the original poster remains optimistic, citing others' successful results.

      community Any chemists want to manufacture PP405 / JXL069? (Steps inside)

      in Research/Science  114 upvotes 1 year ago
      The conversation discusses the potential of PP405 as a hair loss treatment, with some users expressing skepticism and others hopeful about its development. There is also mention of other treatments like Minoxidil, Finasteride, and Pyrilutamide, with users debating the effectiveness and safety of self-experimentation versus waiting for clinical trial results.

      community So happy with my progress :) (25M)

      in Progress Pictures  53 upvotes 10 months ago
      A 25-year-old male is happy with his hair regrowth progress after using Dutasteride (0.5mg), Minoxidil (5mg), Zinc, and Biotin for nearly five months. He reports visible improvement, reduced insecurity, and shares cost details of his treatment in Chile.