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      community Anyone here using both Alfatradiol and Fluridil?

      in Treatment  5 upvotes 4 years ago
      User asks if stacking Alfatradiol and Fluridil is effective for hair loss. Alfatradiol is a weaker, topical 5ar inhibitor, while Fluridil is an anti-androgen preventing DHT binding to hair follicles.

      community 4 years of dutasteride monotherapy

      in Progress Pictures  191 upvotes 2 years ago
      The conclusion of the conversation is that the user experienced noticeable regrowth of hair after using dutasteride as a single treatment for about 1.5 years. No before photos were available.

      community Can you beat this 104 year old man‘s hair count?

      in Styling  752 upvotes 3 years ago
      A 104 year old man's impressive head of hair and speculations about how he has been able to maintain it; treatments such as minoxidil, finasteride, RU58841, dutasteride, 5-AR blockers, and other supplements are discussed.

      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 1 year ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

      community My DHT-blocking protocol, I'm exited!

       6 upvotes 6 years ago
      The post discusses a hair loss treatment regimen using saw palmetto, pumpkin seed oil extract, EGCG (green tea) extract, grape seed oil extract, rosemary oil extract, and Zix. The user plans to use these DHT-blockers and 5AR inhibitors for six months and report the results.

      community "DHT Itch" and onset Seborrheic Dermatitis

      in Research/Science  76 upvotes 2 years ago
      The post and conversation discuss the link between DHT (a hormone), scalp itchiness, and hair loss. Some users share their experiences and treatments, including the use of fluconazole, corticosteroids, and ketoconazole shampoo, with one user suspecting minoxidil as a potential cause of their symptoms.

      community Do these two supplements inhibit 5alpha-reductase?

      in Chat  1 upvotes 5 years ago
      Pumpkin Seed Oil and Perilla Oil (with alpha-lipoic acid, linoleic acid, and oleic acid) are discussed as potential 5alpha-reductase inhibitors. The conversation focuses on their effectiveness for hair loss treatment.

      community What about cofactor NADPH ? Why don't we ever talk about it ?

      in Research/Science  11 upvotes 2 years ago
      The conversation discusses the role of NADPH in hair loss and the potential impact of creatine and B complex vitamins on hair shedding. The user theorizes that increasing NAD levels with B complex vitamins may reduce hair shedding, despite using finasteride and minoxidil for 9 months.

      community Dermaneedling+minox+tretinoin+azaleic acid and hair loss

      in Minoxidil  1 upvotes 3 months ago
      The user stopped oral treatments due to side effects and switched to a regimen of topical minoxidil, tretinoin, azelaic acid, and dermaneedling, with recent addition of topical finasteride. They are questioning the long-term effectiveness of non-hormonal methods and considering hair transplantation.

      community Finasteride does deplete important nuero-active steroids

      in Research/Science  10 upvotes 2 years ago
      Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.

      community Does anyone have experience with topical dut?

      in Finasteride/Dutasteride  8 upvotes 3 years ago
      The user has been using minoxidil for hair loss and is considering trying a compounded topical treatment with 0.1% dutasteride, minoxidil, tretinoin, collagen, and silicon, as recommended by a trichologist. They learned that dutasteride might be more effective than finasteride and are seeking opinions on the use of topical dutasteride.
      27M on Finasteride/Minoxidil 8-9 Months, Considering Dutasteride for Hair Loss

      community 27M on Finasteride/Minoxidil 8-9 Months, Considering Dutasteride for Hair Loss

      in Finasteride  71 upvotes 6 months ago
      The user has been using finasteride and minoxidil for 8-9 months without significant improvement in hair loss and is considering switching to dutasteride and topical minoxidil. Another user suggests that dutasteride might be more effective due to its potency and advises patience as hair regrowth can take up to a year.

      community Can I switch from Min to Nanoxidil?

      in Minoxidil  1 upvotes 1 year ago
      The user is considering switching from Minoxidil to Nanoxidil due to severe fatigue while continuing with Topical Finasteride and oral Dutasteride. They hope to maintain hair gains without the side effects of Minoxidil.

      community Very reluctantly starting Finasteride.

      in Finasteride/Dutasteride  84 upvotes 2 years ago
      A 23-year-old started taking 0.25 mg of Finasteride daily for hair loss after trying Minoxidil and derma rolling without success. People shared varied experiences with Finasteride, discussing potential side effects, effectiveness, and personal decisions regarding hair loss treatment.

      community 2 month progress with Minoxidil and Dermaroller

      in Minoxidil  412 upvotes 2 years ago
      The conversation discusses a user's two-month hair regrowth progress using Minoxidil and a 0.5mm dermaroller. Some suggest adding a 5-alpha-reductase inhibitor like finasteride or dutasteride to maintain the results.

      community We Are So Back. 10 Months Difference

      in Progress Pictures  1210 upvotes 5 months ago
      The user experienced significant hair regrowth over 10 months by using 1.5mg oral finasteride and minoxidil daily, along with weekly derma stamping, after a previous hair transplant and initial thinning. The conversation highlights the importance of using DHT blockers post-transplant to maintain results.

      community Testosterone and Estradiol levels on 1 mg/day dutasteride

      in Finasteride/Dutasteride  44 upvotes 6 months ago
      A 30-year-old man experienced significant hair regrowth and improved libido after using finasteride and dutasteride for androgenetic alopecia, with no adverse effects. He plans to reduce dutasteride dosage when trying to conceive and has been using topical minoxidil since 2015.

      community Sugar and Hair loss connections

      in Research/Science  41 upvotes 10 months ago
      High sugar diets may worsen hair loss by increasing 5α-reductase activity and androgen levels, especially in women with PCOS. A low sugar diet might reduce scalp DHT levels, similar to finasteride, but genetics also significantly influence hair loss.

      community Minoxidil + Microneedling, 2 months results

      in Progress Pictures  20 upvotes 1 year ago
      The user has been using minoxidil twice daily for 2.5 months to treat hair loss and has seen great results, despite only microneedling once at the start. They occasionally forget a dose but it hasn't affected their positive outcome.

      community How to know if shedding is from tren or minoxidil?

      in Minoxidil  5 upvotes 2 years ago
      The user started using trenbolone and minoxidil simultaneously and experienced increased hair shedding, unsure which is causing it. Replies suggest both drugs could cause hair loss, with one advising to stop trenbolone to protect hair and another indicating minoxidil is unlikely the cause due to the timing.

      community Fin bad responder? My experience

      in Finasteride/Dutasteride  2 upvotes 4 years ago
      The user experienced side effects from ecklonia cava similar to those reported with finasteride, including depression, brain fog, anxiety, and testicular pain. Despite these issues, the user is still considering using topical finasteride in the future.