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      community PP405 Update and My Take on Pelage

      in Research/Science  86 upvotes 6 months ago
      Pelage Pharmaceuticals raised $120M for their hair loss treatment, PP405, showing strong investor confidence despite limited data. There is skepticism about its efficacy and long-term effects compared to treatments like GT20029.

      community Seen Alfatradiol mentioned on here a few times recently and found this study - in case anybody is interested. Translated from German.

      in Treatment  5 upvotes 4 years ago
      Alfatradiol (0.025%) is an effective and safe treatment for androgenetic alopecia in both men and women, increasing anagen hair rates with minimal side effects. Users discuss its cost-effectiveness and ease of use compared to other treatments like finasteride and RU58841, with some combining it with stemoxydine and Minoxidil.

      community 1.5 month progress ( 2x Minoxidil a day+ microneedling)

      in Progress Pictures  131 upvotes 3 years ago
      This conversation is about a user's progress pictures after using minoxidil twice a day and microneedling for 1.5 months, with other users recommending finasteride as an additional treatment. They are also discussing the frequency and depth of the microneedling.

      community Reducing Fibrosis in Hair Loss: Topical Pirfenidone

      in Research/Science  57 upvotes 4 weeks ago
      Topical pirfenidone is highlighted as an effective anti-inflammatory and anti-fibrotic treatment for hair loss, particularly in addressing perifollicular fibrosis, which may enhance the effectiveness of standard treatments like finasteride and minoxidil. The user also uses calcipotriol, MCT oil, ciclopirox shampoo, and benzoyl peroxide shampoo as part of their regimen.

      community Any experience with Laduora massage brush

      in Technology  3 upvotes 1 year ago
      The conversation is about the effectiveness of the Laduora duo massage brush for hair regrowth using vibration and red light, and whether the vitamin gel pods make sense. Specific treatments like Minoxidil, finasteride, and RU58841 are not mentioned.

      community My personal experience/observations fighting AGA seriously for 5 years

      in Treatment  47 upvotes 1 year ago
      Minoxidil with alcohol and propylene glycol was more effective than non-alcohol versions, and RU58841 worked best in a non-water-based solution. Oral finasteride showed better results than topical, despite side effects; microneedling and tretinoin worsened hair loss, and PRP was only helpful when younger.

      community My experience with Bosley in California

       38 upvotes 7 years ago
      The user felt pressured during a hair transplant consultation at Bosley, where they were advised to undergo FUT surgery and use a laser cap for maintenance, but did not meet with a doctor. Other users recommended seeking a second opinion from reputable doctors like Dr. Rassman and suggested trying finasteride first.

      community Pp405 - it has to work. It has to.

      in Research/Science  171 upvotes 1 month ago
      Hair loss treatments, including PP405, minoxidil, finasteride, and RU58841, with hopes for future solutions. Participants discuss the emotional impact of hair loss and consider alternatives like hair transplants or acceptance.

      community The Big Fat Layer II

      in Research/Science  26 upvotes 5 years ago
      Hair loss treatment should target dermal white adipose tissue (DWAT) to restore hair follicles. Potential remedies include tocopherol (vitamin E), botox, rosiglitazone, niacin, kojyl cinnamate esters, and ADP355.
      Feedback on Hair Repair Clinic 5% Minoxidil Cream vs. Sons 5% Spray

      community Feedback on Hair Repair Clinic 5% Minoxidil Cream vs. Sons 5% Spray

      in General  119 upvotes 3 months ago
      A user is considering switching from a 5% minoxidil spray to a minoxidil cream for easier application and less greasiness. They are inquiring about the Hair Repair Clinic 5% minoxidil cream, which includes optional tretinoin and other ingredients like isopropyl myristate and beeswax.

      community 3.5 month on fin min dermaroller

      in Is this regrowth?  18 upvotes 1 year ago
      The conversation discusses hair regrowth using finasteride, minoxidil, and a dermaroller. Users also talk about the benefits of using a stamp over a derma roller for scalp treatment.

      community Microneedling + Min 2 months progress

      in Progress Pictures  1067 upvotes 2 years ago
      The post and conversation are about a user's progress with microneedling and minoxidil for hair loss. The user is happy with the progress and plans to continue with the treatment, without using finasteride.

      community Month 2.5 redo. Topical fin/min microneedling once a week.

      in Progress Pictures  18 upvotes 2 years ago
      A user who initially had positive results with oral finasteride, topical minoxidil, and microneedling for hair loss, but experienced side effects like fog and depression. After stopping and losing progress, they restarted with topical treatments and microneedling, reporting good results and no side effects.

      community Combine minoxidil, tazarotene, lumigan

      in Treatment  3 upvotes 9 months ago
      Combining minoxidil 5%, tazarotene 0.1% cream, and lumigan for hair loss treatment is discussed. The conversation focuses on the safety and effectiveness of using these treatments together.

      community Microneedling technique clarification

      in Microneedling  16 upvotes 1 year ago
      The conversation is about using a Dr. Pen for microneedling on a widow's peak, with advice to use a depth of 1.25mm and hold it in place for 10 seconds. The user is also using minoxidil.

      community How can I get this spot more filled in? (Before & After)

      in Is this regrowth?  12 upvotes 1 year ago
      The user has been using a daily topical spray of finasteride and minoxidil, along with occasional microneedling, to address hair loss since August 2023, and is considering switching to oral medication for convenience and cost reasons. Despite progress, they are exploring options like increasing microneedling frequency or potentially undergoing a hair transplant to address a stubborn spot.

      community bpc-157 scalp injections. 3 months

      in Progress Pictures  52 upvotes 3 months ago
      The user experienced reduced hair shedding after three months of injecting 1mg BPC-157 into the scalp, while continuing to use dutasteride and minoxidil. The injections are painful, and the user sometimes switches to injecting into the buttocks.

      community Time for that update again. After 4mos of fin/min/microneedling

      in Update  54 upvotes 10 months ago
      The user is updating on their hair loss treatment progress after 4 months using oral finasteride, topical minoxidil spray, and weekly 1mm dermarolling. The crown area is slowly improving, with a smaller bald spot radius compared to the previous month.

      community Pp405 - lowkey kinda bad results

      in Treatment  16 upvotes 10 months ago
      PP405 increased hair density by 20% in 31% of participants, but results are considered underwhelming. Minoxidil and finasteride are seen as more effective treatments.

      community Replacing Microneedling with Lice?

      in Chat  70 upvotes 9 months ago
      Using lice as an alternative to microneedling for hair loss treatment, with concerns about effectiveness and practicality. Some users humorously suggest genetically altering lice to produce beneficial compounds.

      community GT20029 Big Phase 2 Update Results!

      in Research/Science  53 upvotes 4 months ago
      GT20029 showed promising results for hair growth in a Phase II trial, with the 1.0% twice-weekly regimen being the most effective. Some users expressed skepticism and humor about the product's effects and market availability.

      community It looks like Pelage are giving hints that PP405 is a game changer

      in Chat  243 upvotes 4 weeks ago
      PP405 is seen as a potential breakthrough for converting vellus hairs to terminal hairs, with users expressing both hope and skepticism. It is compared to treatments like minoxidil and finasteride, with discussions on side effects and marketing concerns.

      community 3 months update (min, fin, microneedle, ketocanozal)

      in Progress Pictures  11 upvotes 2 years ago
      The user has been using 5% Minoxidil foam for three months, 1mg Finasteride for 1.5 months, weekly derma stamping, and Ketoconazole shampoo twice a week for hair loss treatment. They have not noticed any improvement since February and are concerned about baby hair falling out when applying Minoxidil and shampooing.