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community The story of RU58841/PSK3841

in Research/Science 1 year ago

RU58841, an anti-androgenic compound, showed early promise for treating alopecia but faced challenges after its patent in 1997. Despite advancing to Phase II trials, safety concerns and financial struggles led Aventis to abandon its development. Proskelia, which later merged into ProStrakan, couldn't prioritize the drug, leading to its eventual stagnation and failure to reach the market.

community Switched from Fin to Dut —Need Advice

in Treatment 7 upvotes 10 months ago

The user switched from finasteride to dutasteride due to continued hair thinning and is seeking advice on whether to continue with dutasteride, while also using minoxidil, topical finasteride, retinoic acid, and ketoconazole shampoo. Responses suggest sticking with dutasteride as it is considered a potent treatment, though experiences vary.

community [PSA] - Do NOT swallow dutasteride capsule content.

in Finasteride/Dutasteride 41 upvotes 6 months ago

Dutasteride capsules should not be bitten or opened due to their foul taste and potential caustic effects. Users shared experiences of accidentally biting capsules and the unpleasant taste, with some suggesting swallowing techniques to avoid this.

community Can I start dut and ru at the same time

in Finasteride/Dutasteride 2 upvotes 5 months ago

The user has been using finasteride for almost two years but is considering switching to dutasteride and is curious about adding RU58841. They decide to stick with dutasteride due to concerns about RU58841's safety.

community Progress at ~6 month mark dut/min

in Progress Pictures 12 upvotes 3 months ago

A user shared their 6-month progress using daily oral dutasteride and minoxidil, along with monthly mesotherapy including zinc, dutasteride, minoxidil, biotin, and panthenol, reporting no noticeable side effects. Encouragement was given to continue despite potential hair shedding.

community 1MG FIN 4 years then HT now for past 6 months 0.5 DUT and 2.5 Oral Min twice daily

in Progress Pictures 170 upvotes 1 year ago

OP used 1mg finasteride for 4 years, then had a hair transplant, and for the past 6 months has been using 0.5mg dutasteride and 2.5mg oral minoxidil twice daily. The treatments resulted in significant hair density and thickness improvement.

community pyrilutamide GB update please? Anything no matter how big or small

in Update 34 upvotes 4 years ago

The effects of Finasteride on hair loss and its side-effects, such as aching balls. The user has been taking it for two years with no changes to the symptom.

community 2 years fin only 1mg/daily + 4 months of gradually introducing Dut 0.5mg/daily

in Progress Pictures 1708 upvotes 9 months ago

A user experienced significant hair regrowth using finasteride 1 mg daily for two years and gradually introduced dutasteride 0.5 mg daily over four months. They reported no side effects and plan to switch fully to dutasteride due to its cost-effectiveness and potential effectiveness.

community Is this good progress? 24M 6 months 2.5mg minoxidil and 3 months 0.5mg dutasteride EOD

in Progress Pictures 610 upvotes 1 year ago

A 24-year-old male achieved significant hair regrowth using 2.5mg oral minoxidil and 0.5mg dutasteride every other day, with no side effects and increased libido. Revita shampoo and conditioner were also used but were less effective than the medications.

community any news about DUPA (Diffuse unpatterned alopecia)?

in Research/Science 8 upvotes 3 years ago

The conversation discusses diffuse unpatterned alopecia (DUPA) and its possible causes, including sensitivity to DHT, not being androgenic alopecia, being diffuse alopecia areata, or hormonal issues. Treatments mentioned include topical melatonin, Clobetasol Propionate for alopecia areata, and the lack of results from using finasteride, dutasteride, and minoxidil.

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