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      community Ru58841 made my hair worse

      in General  138 upvotes 1 year ago
      RU58841 worsened hair condition, causing thinning and unusual patterns. The user stopped using it two months ago but hasn't seen recovery, and there's speculation about androgen receptor upregulation.

      community What happens if you combine dutasteride and a aromataze inhibitor?

      in Question  4 upvotes 7 years ago
      Combining dutasteride and an aromatase inhibitor may increase testosterone levels significantly, potentially enhancing athletic performance but also posing health risks like elevated blood pressure and worsened cholesterol. The user is experimenting with dutasteride, anastrozole, minoxidil, and ketoconazole shampoo to manage hair loss and estradiol levels, while monitoring side effects and hormone levels.

      community Who won’t respond to minoxidil? (Studies)

      in Research/Science  33 upvotes 3 months ago
      Minoxidil's effectiveness varies due to differences in sulfotransferase enzyme levels in the scalp, affecting people with conditions like ASD, liver disease, and androgenic alopecia. Treatments like topical tretinoin, microneedling, and using minoxidil sulfate instead of regular minoxidil can improve results for those with low enzyme levels.

      community Female male-pattern AGA- seeking help

      in Female  1 upvotes 2 years ago
      A female with male-pattern hair loss (AGA) is seeking help after unsuccessful treatments with spironolactone and supplements, and is considering oral minoxidil and finasteride despite concerns about medication side effects. She has ruled out hormonal birth control and PRP/PRFM, and is looking into further medical advice due to abnormal lab results.

      community This and ketoconazole 2% life changing

      in Ketoconazole  69 upvotes 2 years ago
      The post discusses the user's experience with hair loss treatment using finasteride, clobetasol propionate, and ketoconazole shampoo. The conversation warns about the potential side effects of clobetasol, a powerful topical steroid, and emphasizes its short-term usage.

      community 24M, 0.5 Dut, 2.5mg Min, 10mg Biotin. 2 month crown update.

      in Progress Pictures  30 upvotes 5 months ago
      A 24-year-old male shares his two-month progress on hair regrowth using 0.5mg Dutasteride, 2.5mg Minoxidil, 10mg Biotin, and Ketoconazole shampoo, noting significant crown improvement. Users discuss the effectiveness of oral Minoxidil, with some expressing skepticism about photo angles and the necessity of Biotin unless deficient.

      community Spironolactone and pregnancy planning

      in Female  2 upvotes 1 year ago
      A user with AGA uses topical spironolactone 2% due to side effects from the oral form and is concerned about its use during conception and breastfeeding. They seek alternatives to prevent AGA relapse while planning pregnancy and after childbirth.

      community Tretinoin .. beneficial or hindrance?

      in Treatment  6 upvotes 6 months ago
      Tretinoin combined with minoxidil may improve hair regrowth, especially in difficult areas like temples, but requires diligent scalp cleaning. Some users suggest oral minoxidil as a more potent and less irritating alternative.

      community 10 day solo pyrilutamide update

      in Chat  11 upvotes 3 years ago
      The user started using pyrilutamide for hair loss on January 24, applying 1ml daily without other treatments, and after 10 days noticed reduced hair shedding and improved hair quality, with plans to continue for at least 6 months. They experienced chest pain initially, which could be related to starting methylphenidate or pyrilutamide, but the pain has since subsided.

      community Dutasteride broked my liver (maybe)

      in Finasteride/Dutasteride  8 upvotes 3 years ago
      A user shared their experience with high cholesterol, glucose, and potential metabolic syndrome after using Finasteride and Dutasteride for hair loss. They plan to improve their health with diet and exercise before considering medication.

      community 5 weeks tretinoin, severe shed and thinning.

      in Minoxidil  3 upvotes 4 months ago
      The user has been using minoxidil for 5 years and finasteride for 7 months, with recent addition of tretinoin cream causing significant hair shedding. Other users suggest the shedding indicates effectiveness and recommend continuing tretinoin use.

      community Longtime Creatine Users, Good/Bad Experiences?

      in Chat  16 upvotes 9 months ago
      Creatine use is linked to increased hair shedding for some, especially those with DHT sensitivity, but experiences vary. Some users manage hair loss with treatments like finasteride, minoxidil, or dutasteride, while others stop creatine to reduce shedding.

      community How do i use tretinoin on the scalp?

      in Treatment  2 upvotes 3 months ago
      The conversation is about applying tretinoin on the scalp for hair loss, with tips on mixing it with minoxidil foam and using a thin layer to avoid flaking and dryness. Suggestions include exfoliating with rosemary or coconut oil and wearing a hat for sun protection.

      community Koshine 1% application Amazon vs main site

      in Technology  1 upvotes 1 year ago
      The conversation discusses the application frequency of Koshine 1% for hair loss, with conflicting instructions between Amazon and the main website. The user is unsure whether to apply it once or twice daily.

      community Gt20026 - the actual cure to hairloss?

      in Research/Science 3 months ago
      GT20026 is discussed as a potential treatment for hair loss that targets androgen receptors without affecting hormone levels, but it may not promote significant regrowth. It is expected to be available by 2028, with other treatments like Breezula and Clascoterone also mentioned.

      community Growth stimulants worth a damn besides minox?

      in Minoxidil  3 upvotes 2 years ago
      The user experiences side effects from minoxidil and is considering alternatives like stemoxydine and adenosine for hair regrowth and density, but finds options like caffeine and various oils unreliable. They are also using a 5AR inhibitor (finasteride).

      community BPC-157 and Angiogenesis. Bro-Science-Execution-Plan

      in Research/Science  13 upvotes 11 months ago
      BPC-157 may promote hair growth by increasing angiogenesis, similar to how Minoxidil works, though no direct research confirms this yet. Users report combining BPC-157 with Minoxidil and finasteride for better results, but concerns about long-term safety exist.

      community Improvement or Delusional? 21M

      in Is this regrowth?  4 upvotes 1 year ago
      A user is using topical finasteride, keto shampoo, microneedling, and tretinoin for hair loss and is considering adding pyrilutamide. They notice some improvement at the temples and seek advice on whether to focus on cosmetic results despite daily shedding.

      community So I hacked the AAD 2026 live stream

      in Chat  42 upvotes 2 months ago
      The conversation discusses a live stream presentation on Pelage PP405 for hair regrowth, with skepticism about its effectiveness compared to minoxidil. Some users express doubt and suggest sticking to proven treatments like minoxidil, finasteride, and RU58841.