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      community Day 0 - 33 - 31M min 5%, Dut 0.5mg/daily, + more

      in Progress Pictures  5 upvotes 1 year ago
      A 31-year-old male is using a hair loss treatment routine that includes daily 0.5mg dutasteride, 5% minoxidil, microneedling, biotin, vitamin D, omega-3 supplements, and alternating shampoos to restore hair density. He reports no side effects or noticeable regrowth yet but feels optimistic about the process.

      community Starting ketoconzole. How much and How many times a week?

      in Ketoconazole  12 upvotes 1 year ago
      A user is experiencing severe dandruff and hair loss, considering using ketoconazole shampoo 2% to manage these issues. They seek advice on application frequency and effectiveness, with suggestions to use it 2-3 times a week and to consider other treatments like finasteride for hair loss.

      community Why Diffuse Thinning is Worse Than a Receding Hairline

      in Research/Science  149 upvotes 1 year ago
      Diffuse thinning is worse than a receding hairline as it affects the entire scalp, complicating styling and hair transplants. Treatments like finasteride, minoxidil, dutasteride, and RU58841 are mentioned, with some users noting improved hair density.

      community What else is good. Besides the big 3.

      in Chat  35 upvotes 1 year ago
      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

      community DHT is about to get smashed ….

      in Update  801 upvotes 1 year ago
      The conversation discusses hair loss treatments like topical finasteride with minoxidil, oral dutasteride, and essential oils. Oral treatments like dutasteride and finasteride are seen as more effective, though some prefer topicals to avoid side effects.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Topical finasteride now the safest possible path?

      in Finasteride/Dutasteride  84 upvotes 1 year ago
      Topical finasteride is considered a safer option for hair regrowth with fewer systemic side effects compared to oral finasteride. Some users report similar efficacy and side effects between topical and oral treatments, while others prefer topical due to reduced systemic exposure.

      community 3 months progress pics (20 days ago)

      in Progress Pictures  243 upvotes 1 year ago
      A user shared their 3-month hair loss treatment progress using 5% minoxidil, 1mg finasteride, and occasional nizoral. They noted significant progress and plan to continue treatments, with another update at the 6-month mark.

      community Dutasteride Literally Saves Your Hair

      in Finasteride/Dutasteride  101 upvotes 1 year ago
      Dutasteride significantly reduces scalp DHT levels and can save hair, though shedding is part of the process. Some users report success with dutasteride, while others struggle despite using it along with finasteride and oral minoxidil.

      community HMI 115 Phase 2 - Leaked pics from Discord

      in Research/Science  362 upvotes 2 years ago
      The conversation discusses HMI 115, a new hair loss treatment with promising results, showing a significant increase in hair density after two months. Some users are skeptical, while others are hopeful for its release and potential affordability.

      community Does it work? Maneup GHK-Cu hair growth serum

      in Treatment  8 upvotes 2 years ago
      The conversation is about the effectiveness of Maneup GHK-Cu hair growth serum, a topical treatment for hair loss. The user is considering trying it but is skeptical due to issues others have had with DIY injections of a similar substance.

      community 6 months on biotin + minoxidil

      in Progress Pictures  357 upvotes 2 years ago
      A user shared a 6-month progress picture showing improvement in hair loss using biotin and minoxidil. They also mentioned dealing with stress, diet issues, and seborrheic dermatitis.

      community New Treatments, and a Huge Group Buy with Lots of Research

      in Research/Science  109 upvotes 2 years ago
      A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

      community Leaving the fight. Got buzzed.

      in Shaved/buzzed  271 upvotes 2 years ago
      The conclusion of the conversation is that the user has decided to embrace their hair loss and has buzzed their head. They plan to continue their current hair loss treatments until they run out of stock. They also mention having dandruff and will continue medication for that.

      community Finasteride does deplete important nuero-active steroids

      in Research/Science  9 upvotes 2 years ago
      Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.

      community The ultimate regiment to reverse hairloss

      in Treatment  5 upvotes 3 years ago
      The conclusion of the conversation is that the user "Shakalakaplaka" shares their comprehensive hair loss regimen, which includes various treatments targeting different pathways such as DHT, inflammation, fibrosis, immune system, testosterone, gut problems, and scalp health. The effectiveness of the regimen is not confirmed, and some users express skepticism or request before and after pictures for credibility.

      community Pyrilutamide from Hairlisciously? Other suppliers?

      in Treatment  8 upvotes 3 years ago
      The conversation is about the effectiveness and trustworthiness of Pyrilutamide hair loss treatment sold by Hairlisciously, with concerns about product purity and a request for alternative suppliers. No specific treatments were confirmed to be used by participants.

      community Anything you use without scientific backing, just trusting your gut?

      in Research/Science  13 upvotes 3 years ago
      The conversation discusses using peppermint oil for hair loss, with one user applying it undiluted to the scalp and another combining it with finasteride and microneedling. Some believe in its effectiveness despite limited scientific evidence, and also mention rosemary oil as potentially beneficial.