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      community Oral Minoxidil and Grapefruit Juice

      in Research/Science  96 upvotes 2 years ago
      The conversation is about the potential dangers of taking oral minoxidil and grapefruit juice together. Some users express concern about dangerous drug interactions, while others argue that grapefruit juice may inhibit the metabolism of finasteride. The conclusion is that grapefruit juice may make finasteride less effective, but it won't affect minoxidil.

      community Why hasn’t anyone made a "DHT sponge" biologic yet???

      in Research/Science  45 upvotes 4 months ago
      The conversation discusses the potential for developing a biologic "DHT sponge" to neutralize DHT in the bloodstream as a treatment for hair loss, suggesting it could be more targeted and have fewer side effects than current treatments like finasteride and dutasteride. Concerns include the complexity, cost, and potential side effects of such a treatment, as well as skepticism about its feasibility and market interest.

      community DHT Gel (2.5%) to beard area + Dut + Pyri 1% + Minox

      in Research/Science  5 upvotes 6 months ago
      The conversation discusses using a combination of DHT gel, dutasteride, pyrilutamide, and minoxidil to promote beard growth while minimizing hair loss. Users suggest consulting a doctor and considering genetic factors before proceeding.

      community If PP405 goes systemic this would be quite catastrophic

      in Research/Science  5 upvotes 1 year ago
      Concerns about the potential systemic effects and safety of PP405 for hair loss, with discussions on its comparison to existing treatments like finasteride and minoxidil. Users express skepticism about untested research chemicals and emphasize the importance of clinical trials to ensure safety and efficacy.

      community Deoxyribose sugar gel worked just as well as minoxidil

      in Research/Science  18 upvotes 1 year ago
      A deoxyribose sugar gel may work as well as minoxidil for hair regrowth by boosting blood supply to hair follicles. Some users discuss combining it with minoxidil and cetrizine, but caution is advised due to potential risks and lack of consistent results.

      community Oral Minoxidil - The Hyper-Responder Concept

      in Research/Science  4 upvotes 5 months ago
      Minoxidil's effectiveness varies due to genetic differences in the SULT1A1 enzyme, affecting how well it converts to its active form, minoxidil sulfate. Hyper-responders may experience rapid hair growth and increased side effects, such as pericardial effusion, even at low doses.

      community What is worth dissolving in topical minoxidil solution?

      in Treatment  3 upvotes 1 year ago
      Switching from minoxidil foam to topical solution and considering adding caffeine, melatonin, or cetirizine. Currently using 2.5mg oral minoxidil and 1mg oral finasteride, planning to ask for 0.5mg oral dutasteride and 5mg oral minoxidil.

      community Anybody here cooking oral minoxidil?

      in Minoxidil  25 upvotes 5 months ago
      The conversation is about making oral minoxidil pills for personal use, including inquiries about ingredients and binders. The user mentions taking 2.5mg of oral minoxidil daily.

      community How I stopped minoxidil build up on my scalp.

      in Minoxidil  46 upvotes 1 year ago
      Switching from minoxidil with propylene glycol to a glycerin-based solution helped reduce scalp buildup and dandruff. Using ketoconazole shampoo and a scalp massager also improved scalp health.

      community Science backed answer only from what you have learnt .

      in Chat  4 upvotes 1 year ago
      Alcohol-based minoxidil absorbs better but can cause irritation; non-alcohol-based is gentler. Topical dutasteride shows promise but needs more research; low-dose oral minoxidil (0.25 mg/day) is effective with fewer side effects. Ingredients like Procapil, Redensyl, caffeine, and Anagain in shampoos have limited evidence; ketoconazole shampoo can help when used 2-3 times a week with other treatments.

      community Pattern hair loss could be due to gut bacteria

       51 upvotes 6 years ago
      Feeding bacteria-free mice with Lactobacillus murinus worsened hair loss, but a regular diet with biotin stopped it. The conversation suggests gut bacteria and diet may influence hair loss, with some skepticism and discussion about other factors like DHT and genetics.

      community Minoxidil Sulfate makes everyone a responder

      in Research/Science  260 upvotes 1 year ago
      Minoxidil sulfate is more effective than regular minoxidil, especially for those with low sulfotransferase levels or scalp sensitivity, but it is unstable unless delivered in a liposomal format. Combining minoxidil with tretinoin can enhance effectiveness, and stopping minoxidil use can lead to rapid hair loss.

      community I'm about to order some retinol and azelaic acid from the ordinary

      in Product  44 upvotes 5 years ago
      The conversation discusses using retinol to enhance minoxidil's effectiveness for hair loss, with a user considering The Ordinary's 0.5% retinol and seeking advice on azelaic acid concentration. Other users suggest using tretinoin instead and consider pre-formulated products combining minoxidil, tretinoin, and azelaic acid, but the original poster has not seen improvement from dermarolling.

      community Anyone have experience with 82M?

      in Question 8 years ago
      A user with diffuse thinning, currently using finasteride, biotin, minoxidil, and nizoral shampoo, is considering a topical solution called "82M" but is skeptical due to its high cost and lack of supporting research. They seek others' experiences with "82M."

      community Dry and itchy scalp after ru58841 and keto. Advice needed

      in Product  3 upvotes 4 years ago
      The user experienced severe scalp itching after using RU58841 and ketoconazole shampoo, despite trying moisturizing treatments. They suspect the issue is related to the propylene glycol in the vehicle and are seeking alternatives.
      Feedback on Hair Repair Clinic 5% Minoxidil Cream vs. Sons 5% Spray

      community Feedback on Hair Repair Clinic 5% Minoxidil Cream vs. Sons 5% Spray

      in General  119 upvotes 3 months ago
      A user is considering switching from a 5% minoxidil spray to a minoxidil cream for easier application and less greasiness. They are inquiring about the Hair Repair Clinic 5% minoxidil cream, which includes optional tretinoin and other ingredients like isopropyl myristate and beeswax.

      community Dandruff and Topical Solutions

      in Finasteride/Dutasteride  2 upvotes 1 year ago
      The user is using a topical solution with finasteride, minoxidil, and retinoic acid, which causes scalp residue and dryness. They seek advice on removing residue and keeping the scalp moisturized.

      community Kirkland Minoxidil 5% Foam Canada Issue

      in Minoxidil  4 upvotes 4 years ago
      Kirkland Minoxidil 5% Foam is either sold out or very expensive, leading to frustration over limited options without propylene glycol. Alternatives like Rogaine and Foligain are discussed, with varying prices and ingredient differences.

      community Water retention from topical minoxidil

      in Minoxidil  4 upvotes 4 years ago
      Topical minoxidil can cause water retention, making the face appear swollen. Switching from liquid to foam and reducing application frequency may help; using dandelion root extract as a diuretic is also suggested.