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      community It is what it is with some people

      in Satire  162 upvotes 3 months ago
      Hair loss treatments like finasteride and dutasteride are discussed, with concerns about side effects such as depression and brain fog. Some users argue about the necessity and impact of DHT on libido and other bodily functions.

      community (MTF 35) Results of 18 Months of HRT

      in Transgender  775 upvotes 3 months ago
      A transgender woman experienced significant hair regrowth after 18 months of hormone replacement therapy (HRT) with estrogen and bicalutamide. The discussion notes HRT's effectiveness for hair regrowth but warns against its use for cisgender men due to feminizing effects.

      community The expected timeline for PP405 - Next update at AAD Annual Meeting in March 2026 ?

      in Treatment  30 upvotes 3 months ago
      A new hair loss treatment, PP405, showed promising Phase 2a results with 31% of patients experiencing over 20% hair density increase without systemic absorption, avoiding hormonal side effects. The treatment is expected to be expensive, with Phase 3 trials starting mid-2026, and there is skepticism about the data's strength.

      community How safe and/or difficult would it theoretically be to turn raw 99.9% clascoterone into topical formula?

      in Treatment  6 upvotes 3 months ago
      The user discusses their hair regrowth success with minoxidil, red light therapy, massage, and derma stamping but expresses concerns about using finasteride due to potential side effects. They are interested in using clascoterone as a topical treatment for hair loss and are exploring the possibility of creating a topical formula from raw clascoterone powder.

      community How aggressive can I push my stack?

      in Treatments  165 upvotes 4 months ago
      A 21-year-old male is experiencing crown balding and is using RU58841, topical minoxidil, and plans to add dutasteride and oral minoxidil to his treatment. He seeks advice on increasing his treatment stack despite previous side effects like chest pain.
      Can I still save my hairline at age of 15?

      community Can I still save my hairline at age of 15?

      in General  532 upvotes 4 months ago
      A 15-year-old is concerned about hair loss, possibly at Norwood 2 or 3, and is using shampoos and conditioners recommended by a trichologist. Suggestions include considering topical minoxidil and consulting a doctor about topical anti-DHT treatments like finasteride or RU58841, but avoiding 5-alpha-reductase inhibitors at this age.

      community White hair seemed to be turn black, re-pigmentation

      in Update  1 upvotes 4 months ago
      The user experienced hair repigmentation and attributes improvements in hair and overall health to a carnivore diet, Boron, and Selenium supplementation. They stopped using finasteride after 20 years, noticed increased testosterone and libido, and observed hair regrowth with RU58841.

      community Hair loss research is a money grab

      in Chat  227 upvotes 5 months ago
      Hair loss is linked to DHT, with treatments like finasteride and minoxidil being common but not definitive. Economic interests influence research, and there is potential for new treatments like PP405 and RU58841.

      community Do mens shampoo for hair loss help with balding?

      in Research/Science  44 upvotes 5 months ago
      Shampoos, including those with ketoconazole, may offer mild benefits for hair health but are not effective for stopping hair loss or balding. Effective treatments for hair loss include finasteride and minoxidil, often used together, while shampoos are generally not on the scalp long enough to impact hair follicles significantly.

      community Dut 0.5mg ED and oral min 3mg ED 5 months progress

      in Progress Pictures  28 upvotes 5 months ago
      The user is using 0.5mg dutasteride daily and 3mg oral minoxidil daily for hair loss, but hasn't seen improvements after five months. They report miniaturization and thinning, especially at the hairline and crown, and are advised to wait at least a year for better results.

      community Best treatment for receeding hairline

      in General  145 upvotes 5 months ago
      A 21-year-old male is experiencing a receding hairline and has tried tea tree oil and hair growth shampoo without success. He is considering products from companies like Hims, Happy Head, and Dermose for treatment.
      21M on Minoxidil 3 Months: Should I Add Finasteride for Thinning Hair?

      community 21M on Minoxidil 3 Months: Should I Add Finasteride for Thinning Hair?

      in General  246 upvotes 5 months ago
      A 21-year-old male experiencing hair thinning started using Minoxidil, which stopped his shedding and led to the growth of vellus hairs on his temples. He is considering whether to add finasteride to his routine, which currently includes Minoxidil, derma rolling, ketoconazole shampoo, vitamin D3, zinc, and a rosemary and fenugreek lotion.
      M17 regrowth journal

      community M17 regrowth journal

      in Journals / Progress Pictures  144 upvotes 5 months ago
      A 17-year-old is addressing hair loss with finasteride, topical minoxidil, and microneedling. They are considering adding GHK-Cu to their regimen, but others advise caution with finasteride due to age.

      community Any help with female hair loss?

      in Female  2 upvotes 5 months ago
      A 20-year-old female with PCOS is experiencing hair loss and excessive facial hair. She is using ketoconazole and caffeine shampoos, microneedling, and considering anti-androgens like finasteride, but is cautious about minoxidil due to facial hair concerns.

      community Popular hair loss drug linked to higher suicide risk: compared to non-users, finasteride (Proscar/ Propecia) users have a markedly increased risk of depression, anxiety, and suicidal thoughts. Over 30 years of observation, 19,320 suicides were expected.

      in Research/Science  493 upvotes 5 months ago
      Finasteride users may have an increased risk of depression, anxiety, and suicidal thoughts, though some attribute these issues to hair loss itself. The link between finasteride and mental health effects is debated, with varying user experiences.

      community 5 months on dut/fin/min progress

      in Progress Pictures  175 upvotes 6 months ago
      The user experienced significant hair regrowth after 5 months using finasteride, dutasteride, and oral minoxidil, despite initial side effects like erectile dysfunction, which resolved after switching from finasteride to dutasteride. The user reports full recovery of hair density and improved skin condition, though the right temple remains slightly recessed.

      community One year 2.5mg Minoxidil 1.25mg finasteride

      in Progress Pictures  185 upvotes 6 months ago
      A user shared progress pictures after one year of using 2.5mg Minoxidil and 1.25mg Finasteride for hair loss. The discussion includes suggestions for additional treatments like dermastamping, dutasteride, and increasing Minoxidil dosage, with mixed opinions on the effectiveness of current treatments.

      community Finasteride and “anti-aging” effects

      in Treatment  218 upvotes 7 months ago
      Finasteride may help users look younger by suppressing DHT, affecting skin and hair. Users also emphasize skincare, sunscreen, and lifestyle for maintaining a youthful appearance.

      community How to take care of the microneedler?

      in Microneedling  7 upvotes 7 months ago
      Disinfecting microneedlers is important to prevent infection, with suggestions to use high-percentage alcohol or denture tablets for sterilization. Rollers may cause skin damage, so stamps or pens are recommended for safer microneedling.

      community The homeless crackhead protocol

      in Satire  4487 upvotes 7 months ago
      The conversation humorously suggests that drug use might be more effective for hair retention than traditional treatments like minoxidil or finasteride. It attributes full heads of hair in homeless individuals to lifestyle factors like reduced stress or hormonal changes.

      community Nizoral absolutely fucked up my hair

      in Ketoconazole  88 upvotes 7 months ago
      Nizoral shampoo caused significant hair thinning and oiliness for some users, while others found it beneficial for slowing hair loss. The original poster experienced negative effects and was advised to stop using Nizoral and switch to a gentler shampoo.

      community I'm becoming non-responder to minoxidil. What's going on?

      in Minoxidil  7 upvotes 8 months ago
      The user experienced reduced effectiveness of minoxidil after consistent use, despite using dutasteride to maintain hair. They are considering alternatives like microneedling and exploring options like hair transplants due to dissatisfaction with current hair density.