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      community 2ddr thread, I'll try to add to it monthly

      in Research/Science  19 upvotes 1 year ago
      The user is using a hair loss regimen involving 2ddr applied twice daily, tretinoin weekly, and occasionally micro-needling. They report feeling increased scalp thickness and seeing some hair growth progress.

      community Does anyone plan to microneedle their whole life?

      in Microneedling  4 upvotes 6 months ago
      A 19-year-old is concerned about long-term microneedling for hair loss and is unsure if it will remain effective as they age. They experienced side effects from topical finasteride and are considering whether to try it again in the future, while also dealing with body dysmorphia and stress.

      community Can Micro Needling be harmful in long term?

      in Microneedling  10 upvotes 11 months ago
      The conversation discusses the use of microneedling for hair loss, with concerns about potential long-term effects like fibrosis and scarring. Users share experiences and opinions on combining microneedling with treatments like minoxidil and finasteride, but there is uncertainty about the long-term safety and efficacy.

      community Warning: Danish Nordic Hair Growth is scam!

      in Product  86 upvotes 2 years ago
      A Danish citizen warns against NordicHairGrowth.com, claiming it falsely advertises products for treating androgenic alopecia. The company's ingredients and claims are disputed, including a non-existent patented ingredient RP-24, and a non-verifiable clinical trial.

      community Is microneedling supposed to be a blood bath? 1mm dermastamp

      in Microneedling  41 upvotes 2 years ago
      The conversation is about someone experiencing a lot of bleeding from using a 1.0mm microneedling device for hair loss treatment and asking if it's normal. Various users suggest that the bleeding is excessive and recommend using shorter needles or less pressure, while others share their own microneedling practices with different needle lengths and no bleeding.

      community Brothers in baldness any news on pyrilutamide

      in Chat  12 upvotes 3 years ago
      The conversation is about the potential effectiveness of a hair loss treatment called pyrilutamide. One person has been using it since September and reports positive results.
      M17 regrowth journal

      community M17 regrowth journal

      in Journals / Progress Pictures  144 upvotes 8 months ago
      A 17-year-old is addressing hair loss with finasteride, topical minoxidil, and microneedling. They are considering adding GHK-Cu to their regimen, but others advise caution with finasteride due to age.

      community Black seed oil having gunk in it

      in Product  2 upvotes 1 year ago
      User noticed gunk in their black seed oil for hair growth and is concerned it might be bacteria. They are considering whether to throw it away.

      community Ultimate Non-5AR (fin/dut) stack?

      in Treatment  1 upvotes 1 year ago
      The conversation discusses alternatives to 5AR inhibitors for hair loss treatment, suggesting options like minoxidil, KX-826, pyrilutimide, microneedling, and topical bicalutamide. Concerns about side effects and the effectiveness of these treatments are also highlighted.

      community Aggressive diffuse thinning after 1 year of fin and min

      in Progress Pictures  7 upvotes 1 year ago
      The user is experiencing aggressive diffuse thinning despite using 1mg oral finasteride daily, topical minoxidil twice, microneedling, and Nizoral for seborrheic dermatitis. They are considering switching to dutasteride or RU58841 but are advised to seek a second opinion to determine the cause of hair loss.

      community The expected timeline for PP405 - Next update at AAD Annual Meeting in March 2026 ?

      in Treatment  30 upvotes 6 months ago
      A new hair loss treatment, PP405, showed promising Phase 2a results with 31% of patients experiencing over 20% hair density increase without systemic absorption, avoiding hormonal side effects. The treatment is expected to be expensive, with Phase 3 trials starting mid-2026, and there is skepticism about the data's strength.

      community A Short Recap on PP405 and AAD 2026

      in Update 2 months ago
      PP405 is a promising experimental topical treatment for alopecia that reactivates dormant hair follicles by targeting cellular energy, with large-scale trials planned for 2026. While it shows potential, it cannot regenerate permanently destroyed follicles, making hair transplants the only guaranteed solution for advanced baldness currently.

      community Are we underestimating systemic absorption with homemade/generic Topical Fin? (HPCH vs. PG/Ethanol formulations)

      in Research/Science  5 upvotes 5 months ago
      Topical finasteride may have higher systemic absorption and lower efficacy when using a Propylene Glycol/Ethanol formulation compared to the hydroxypropyl chitosan (HPCH) formulation. The safety profile of topical finasteride relies heavily on the HPCH formulation, and using standard solutions might lead to different pharmacokinetics.

      community Almost 3 weeks on Pyrilutamide-Update

      in Update  12 upvotes 3 years ago
      The user has been using Actifolic Pyrilutamide 0.5% once daily for almost three weeks without noticing any side effects or progress. Other users suggest that significant results typically take 3-6 months to appear.

      community Boar bristle or nylon bristle brush?

      in Female  1 upvotes 2 years ago
      A user with medium length hair and thinning at the top is using an adenosine-based hair growth serum and seeking advice on whether to use a boar bristle or nylon bristle brush to stimulate hair growth. They are concerned about their sensitive scalp.

      community How effective is topical spironolactone for androgenic alopecia?

      in Female  1 upvotes 1 year ago
      Topical spironolactone is discussed as a potential treatment for androgenic alopecia, with the user seeking feedback on its effectiveness. Minoxidil, finasteride, and other treatments like microneedling and keto shampoo are mentioned as alternatives.

      community Hair shed is driving me crazy/coping with stress

      in Female  11 upvotes 2 years ago
      A 25-year-old female is experiencing hair loss and has tried PRP, Minoxidil 5% with Biotin, and weekly needling sessions. Her doctor suggested switching to GFC treatment and stopping the needling sessions due to increased shedding, which may be caused by Minoxidil.
      Sudden Triangular Thinning Patch

      community Sudden Triangular Thinning Patch

      in General  157 upvotes 10 months ago
      A 31-year-old has been using finasteride, dutasteride, and oral minoxidil for hair loss. They noticed a sudden triangular thinning patch on their scalp and are seeking advice, questioning if it could be medication-related.