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      community 24M. 5.5 years on minoxidil and almost 5 years on fin/dut

      in Progress Pictures  72 upvotes 5 months ago
      A 24-year-old male shared his 5.5-year progress using minoxidil and nearly 5 years on finasteride/dutasteride for hair loss, reporting no side effects and successful results. He uses 0.5 mg dutasteride daily, oral minoxidil 2.5 mg daily, and topical minoxidil daily, with costs around $4 monthly.

      community Any chemists want to manufacture PP405 / JXL069? (Steps inside)

      in Research/Science  88 upvotes 5 months ago
      The conversation discusses the synthesis and potential use of JXL069 and PP405 for hair loss treatment, with skepticism about their effectiveness and concerns about safety. Users mention that JXL069 has shown no results in hair growth, and there is confusion about its identity and effectiveness compared to PP405.

      community I was very very very very very very very very wrong

      in Ketoconazole  48 upvotes 5 months ago
      Nizoral, a ketoconazole shampoo, can cause scalp dryness and hair shedding if overused. Users discuss alternatives like Selsun Blue, finasteride, and dutasteride for managing hair loss and seborrheic dermatitis.

      community Haircafe video on Min Sulfate, thoughts?

      in Research/Science  101 upvotes 5 months ago
      Minoxidil sulfate is considered for those unresponsive to regular minoxidil, with some trying a 10% formulation from Folligenz. Concerns exist about the product's stability and transparency, but some users report positive initial results.

      community My 6 month journey thus far... 47yo Male.

      in Progress Pictures  425 upvotes 5 months ago
      A 47-year-old male experienced significant hair regrowth over six months using 1mg oral finasteride, 5mg oral minoxidil, and 1ml 5% topical minoxidil, along with weekly derm stamping. He reported no major side effects, improved prostate health, and increased vascularity, with hair texture changes and minor nasal congestion.

      community Dutasteride 8 months in, 2x per week

      in Is this regrowth?  52 upvotes 5 months ago
      The user has been using dutasteride twice a week for 8 months and oral minoxidil for 3 months but is experiencing increased hair thinning. Many recommend taking dutasteride daily for improved results.

      community Can we get a reality check on PP405?

      in Research/Science  83 upvotes 5 months ago
      PP405 is a promising hair loss treatment that may outperform minoxidil and finasteride by reviving dormant follicles and promoting significant regrowth. Results from ongoing trials are awaited, with a potential market release between 2028-2030.

      community P-1075: a BETTER version of Minoxidil

      in Research/Science 6 months ago
      P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.

      community How likely do you think it is for PP405 to come out?

      in Research/Science  21 upvotes 6 months ago
      PP405 is a potential new hair loss treatment that works through metabolic pathways rather than hormonal ones, with an estimated market release between late 2027 and 2029. Current alternatives to finasteride include minoxidil, pyralutamide, fluridil, and RU58841, with hair transplants also being a viable option.

      community Using oral min, fin, biotin for 4 months

      in Is this regrowth?  69 upvotes 6 months ago
      The user has been using oral minoxidil (5mg), finasteride (1mg), and biotin for 4 months with minimal progress in hair regrowth. Other users suggest patience, considering alternative treatments, and note that biotin may not significantly contribute unless there's a deficiency.

      community Balding hair style feedback and advice

      in Styling  127 upvotes 6 months ago
      A 20-year-old with aggressive hair loss is using oral minoxidil and finasteride, considering a buzz cut to manage appearance. Most suggest a buzz cut or shaving, recommending patience with medication and possibly trying RU58841 or dutasteride.

      community Anyone relate but on Finasteride?

      in Finasteride/Dutasteride  465 upvotes 6 months ago
      Finasteride is commonly used for hair loss, with mixed experiences regarding sexual side effects. Some users report no issues, while others experience difficulties, but many find increased confidence and libido.

      community 31M. Just diagnosed with androgenic alopecia. Fears of min.

      in Finasteride/Dutasteride  12 upvotes 6 months ago
      A 31-year-old man with androgenic alopecia is considering treatments like finasteride, minoxidil, and ketoconazole shampoo but is worried about finasteride's side effects. Users recommend starting with finasteride or dutasteride for DHT blocking, suggesting topical solutions to reduce side effects.

      community Progress pictures in the span of 3 months

      in Progress Pictures  53 upvotes 6 months ago
      The user shared progress pictures showing hair improvement over three months using a treatment of 5% minoxidil and 0.1% finasteride solution, along with occasional biotin and multivitamins. Another user discussed their regimen of topical minoxidil, oral minoxidil, finasteride, iron supplements, and dutasteride, seeking advice on application routines.

      community Please tell me there’s actually light at the end of this tunnel.

      in Satire  49 upvotes 7 months ago
      The conversation is about a user experiencing hair shedding after starting a treatment with oral minoxidil, topical minoxidil, and finasteride. Other users reassure that shedding is normal and part of the process, suggesting it will lead to stronger hair growth.

      community Officially 1 Year on Dutasteride and Minoxidil, is this as good as it gets??

      in Chat  28 upvotes 7 months ago
      The user has been using Dutasteride and topical Minoxidil for hair loss, considering switching to oral Minoxidil and increasing Dutasteride dosage. They are seeking advice on whether to change their current regimen or continue, with some users suggesting oral Minoxidil and others cautioning about potential side effects.

      community My experimental hair loss journey under medical supervision: finasteride/dutasteride, oral/topical minoxidil+tretinoin (3-month progress and hair transplant insights for those considering it)

      in Treatment  43 upvotes 7 months ago
      A 23-year-old discusses their hair loss treatment using finasteride, dutasteride, oral and topical minoxidil, and topical tretinoin under medical supervision. They stress stabilizing hair loss before a hair transplant and plan to continue the regimen for at least 18 months.

      community Can we all agree that PP405 is now 4 years away

      in Chat  92 upvotes 7 months ago
      PP405 is expected to be available in 2028, with ongoing discussions about its timeline and potential effectiveness. Current treatments mentioned include sublingual Minoxidil and Vederamicd, with some users experiencing side effects from oral Minoxidil.
      PP405 Identity Research

      community PP405 Identity Research

      in Research  292 upvotes 7 months ago
      PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.

      community Go bald/buzzed, fellas. Your life will improve.

      in Chat  227 upvotes 7 months ago
      Buzzing or shaving your head can boost confidence and save money on hair loss treatments. Some prefer treatments like finasteride and minoxidil to maintain their hair.

      community Zix pre-made - zinc topical on scalp

      in Treatment  3 upvotes 8 months ago
      The user is experimenting with a zinc sulfate and B6 topical solution called "Zix" for hair loss, alongside using a zinc oxide scalp mask and low-level laser therapy (LLLT). They report minimal hair loss after three months of use and are seeking feedback from others who have tried similar treatments.