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      community My Near-Nuclear Stack is Saving me; Hyperresponder?

      in Progress Pictures 1 year ago
      An 18-year-old is using a high-dose hair loss treatment regimen including finasteride, minoxidil, dutasteride, and plans to add RU58841 and bimatoprost, despite warnings from others about the risks. The user is determined to reverse hair loss but acknowledges the potential dangers and does not recommend others follow their approach.

      community RU-58841 without finassteride?

      in Treatment  6 upvotes 10 months ago
      RU58841 is used without finasteride by some due to side effects, with mixed results. Users report combining RU58841 with minoxidil and adjusting finasteride doses to manage hair loss.

      community New 2025 study: high dose oral minoxidil (up to 10mg)

      in Research/Science  80 upvotes 6 months ago
      High-dose oral minoxidil (>5 mg/day) can increase hair density in some men with androgenetic alopecia, but side effects like extra body hair and heart issues are common. Gradual dose increase is advised, but adverse effects may lead to discontinuation or dose adjustments.

      community Duoxidil / Dutasteride/ Minoxidil

      in Minoxidil  83 upvotes 1 year ago
      The conversation discusses a user's positive experience with hair loss treatments, including Duoxidil, oral Dutasteride, oral Minoxidil, and biotin, noting no side effects and effective results. The user plans to start a new cycle of Dutasteride and PRP sessions.

      community PP405 is NOT gray market jxl069

      in Technology  26 upvotes 3 months ago
      PP405 is a safer alternative to JXL069 for hair loss treatment because it penetrates the skin effectively and degrades in the blood, avoiding systemic toxicity. JXL069, when forced into the body, can cause dangerous side effects like lactic acidosis due to its inability to degrade safely.

      community 1% cetirizine (available in allergy medicines) for androgenetic alopecia

       54 upvotes 6 years ago
      The conversation discusses using 1% cetirizine, an antihistamine, as a potential treatment for androgenetic alopecia (hair loss). One user plans to try cetirizine instead of finasteride, while others are curious or skeptical about its effectiveness, discussing the role of inflammation in hair loss.

      community Fluridil/topilutamide experince

      in Treatment  4 upvotes 2 years ago
      A user is trying fluridil/topilutamide for hair loss and experiencing side effects like pain in the testicles and genital discomfort. They previously had adverse effects with finasteride, dutasteride, and RU58841, and are considering other treatments like topical dutasteride and spironolactone for maintenance before a hair transplant.

      community Efficacy and Systemic DHT Suppression of Topical Finasteride vs Dutasteride

      in General  122 upvotes 1 year ago
      Topical dutasteride may have limited absorption due to its higher molecular mass compared to finasteride, potentially affecting its efficacy in suppressing DHT locally. Microneedling might enhance dutasteride absorption, possibly offering stronger local DHT suppression with fewer systemic effects.

      community Finanstride 1mg and oral Minoxidil 2.5 Results

      in Journals / Progress Pictures  65 upvotes 1 year ago
      A 27-year-old male has been using 1mg finasteride and 2.5mg oral minoxidil daily for androgenetic alopecia, seeing good results in 3 months but experiencing thinning and density loss. He seeks advice on his Norwood scale level and when density might return.

      community CAUTION: My Experience with RU58841

      in Treatment  13 upvotes 2 years ago
      The user experienced concerning side effects like throat irritation, shortness of breath, chest pain, and testicle pain after using RU58841 for hair loss, despite also using finasteride and minoxidil. Other users shared mixed experiences, with one advising to stop using RU58841 due to similar side effects, while another reported significant hair loss reduction without side effects.

      community Why is everyone not directly advised Dutasteride?

      in Finasteride/Dutasteride  169 upvotes 1 year ago
      Dutasteride is less commonly prescribed for hair loss because it is not FDA-approved for this purpose, unlike finasteride, which is more accessible and preferred due to fewer side effects. Dutasteride may be more effective in reducing DHT but has a longer half-life and potentially more significant side effects.

      community Anyone looking at peptides for hair?

      in Treatment  9 upvotes 3 months ago
      The conversation discusses interest in peptides for hair loss, specifically mentioning ahkCU and ghkCU. A user is considering adding ghkCU to their treatment regimen.

      community My experience with Alfatradiol so far

      in Treatment  10 upvotes 3 years ago
      User is 16, experiencing hair loss, and using minoxidil and alfatradiol. Shedding decreased, new hairs growing on temples, but unsure if alfatradiol is effective or if future shedding will occur.

      community Any active Kx-826 Pyrilutamide group buys happening?

      in Product  9 upvotes 4 years ago
      The conversation discusses organizing group buys and tracking progress for Kx-826 Pyrilutamide, a hair loss treatment. Participants express optimism about upcoming results and concerns about self-reporting bias.

      community Do you know any alternative to Minoxidil ?

      in Minoxidil  2 upvotes 6 months ago
      The user experienced side effects from oral minoxidil and is seeking alternatives like Stemoxydine, Aminexil, and Redensyl + Procapil. They have been using finasteride for four years and are considering other treatments due to concerns about side effects.

      community Pyrilutamide or RU or cb-03-01?

      in Minoxidil  2 upvotes 5 months ago
      The conversation discusses using Minoxidil, finasteride, RU58841, and pyrilutamide for hair loss treatment. The user is considering adding a topical treatment and has not experienced side effects from current treatments.

      community Serenoa repens (Saw palmetto)

      in Chat  2 upvotes 1 month ago
      Saw palmetto, a 5-alpha reductase inhibitor, caused unexpected side effects like breast changes and altered semen consistency, which resolved after stopping its use. Concerns about similar side effects with finasteride or dutasteride were expressed, and another user reported low libido and depression from saw palmetto.

      community Insane shedding after upping minoxidil dose.

      in Minoxidil  1 upvotes 6 months ago
      The user experienced increased hair loss after increasing their minoxidil dose to 5mg and is considering switching to dutasteride while on testosterone replacement therapy. They are also using finasteride, microneedling, and considering adding Nizoral and caffeine serum to their regimen.

      community Pelage PP405 Phase 2a completed.

      in Research/Science  59 upvotes 2 months ago
      Minoxidil, finasteride, and RU58841 are discussed as treatments for hair loss, with excitement around a new drug, PP405, and a reformulated oral minoxidil in trials. Concerns about cost, side effects, and long-term use are also mentioned.