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      community Oral minoxidil - how important is dermastamping?

      in Microneedling 5 months ago
      A trans woman is using 10 mg oral minoxidil, dutasteride, and estradiol for hair regrowth and is also doing dermastamping despite the pain. Users discuss the benefits of dermastamping for serum absorption and hair follicle stimulation, with some expressing surprise at the high minoxidil dosage.

      community 6 months progress, 4600 grafts in Turkey

      in Progress Pictures  200 upvotes 2 years ago
      The user is happy with their 6-month hair transplant progress of 4600 grafts in Turkey and has been using finasteride for 5 years and minoxidil for 4 years. The donor area is in good condition, potentially allowing for future hair reinforcement.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community progress pics (HRT, fin, min, microneedling) (35, trans non-binary)

      in Transgender  11 upvotes 1 year ago
      A non-binary transfeminine person experienced significant hair regrowth after starting finasteride, minoxidil, microneedling, and hormone replacement therapy with estradiol. They encourage trans individuals concerned about hair loss to consider estrogen as it has greatly improved their hair condition.

      community 2 years on treatment (stack update)

      in Progress Pictures  464 upvotes 1 year ago
      A user shared their hair regrowth progress using Dutasteride, topical Minoxidil, Spironolactone, and Estradiol Valerate injections as part of hormone replacement therapy for transitioning. They experienced significant hair improvement and personal satisfaction but caution against this approach for non-transitioning individuals due to irreversible changes.

      community Will pp405 have to be inserted rectally for full benefits?

      in Transgender  32 upvotes 4 months ago
      Pp405 is discussed as a potential hair loss treatment, with humorous suggestions about rectal administration for increased effectiveness. Users joke about unconventional methods and express willingness to try anything for hair regrowth.

      community New hair institute, Seoul, Dr Ko - 2000 graft no shave fue

      in Transplants  55 upvotes 10 months ago
      A user shared their positive experience with a no shave FUE hair transplant by Dr. Ko in Seoul, including aftercare with oxygen therapy, red light therapy, and prescribed dutasteride and oral minoxidil (2.5mg daily). The procedure cost over $5,000 USD, and the user is satisfied with the results.

      community ABS-201 Trial - What should I know going in

      in Research/Science  25 upvotes 1 month ago
      The conversation is about a user preparing to join the ABS-201 clinical trial for hair loss treatment, which involves a prolactin inhibitor. The user plans to update others on their progress if enrolled.
      Do I have a chance of reversing this without a transplant?

      community Do I have a chance of reversing this without a transplant?

      in General  98 upvotes 1 year ago
      A 19-year-old is seeking advice on reversing hair loss without a transplant, currently using oral finasteride and topical minoxidil. A suggestion was made to switch to dutasteride and use a stronger minoxidil, with the addition of a topical anti-androgen after three months.

      community Exosomes for mpb day 1-? Let’s see if it’s bs.

      in Progress Pictures  3 upvotes 3 years ago
      Trying out a new exosome treatment for male pattern baldness, in addition to increasing vitamin intake and using existing treatments such as Nizoral and scalp drops. The user has no expectations that the new treatment will work but is giving it a try anyway.

      community Dim: high estradiol levels what to do

      in Chat  8 upvotes 1 year ago
      A user is experiencing facial bloating from low-dose topical finasteride due to high estradiol levels and is seeking advice on using DIM to manage this issue, including dosage and brand recommendations.

      community For everyone buying 2-deoxy-d-ribose (2ddr)

      in Research/Science  13 upvotes 1 year ago
      The conversation discusses using 2-deoxy-d-ribose (2DDR) for hair regrowth, with users sharing mixed experiences and side effects like hair loss in new areas and increased anxiety. The original poster plans to continue testing and comparing it to minoxidil, noting potential instability in 2DDR formulations.

      community Veradermics VDPHL01: why isn’t anyone talking about it?

      in Treatment  44 upvotes 1 year ago
      Veradermics' new hair loss treatment, VDPHL01, is likely a modified release oral minoxidil, which has received $75 million in funding for clinical trials. Despite skepticism about investing in a known treatment, some believe it could offer improved efficacy and reduced side effects.

      community Estenove Transplant Review From NYC Guy Mid 20s

      in Transplants  1 upvotes 9 months ago
      The user had a hair transplant with Estenove, rating the overall experience 6/10 due to logistical issues, unmet expectations, and dissatisfaction with the results. They advise against pricier packages and express regret over the asymmetrical hairline, despite good customer service and post-op care.

      community HairClone: Good info from their site

      in Technology  10 upvotes 4 years ago
      HairClone aims to rejuvenate miniaturizing hair follicles through follicle banking and cell expansion, with treatments potentially available in the UK by 2022. The process involves extracting, storing, and cloning hair follicles, but full regenerative treatments will take many years to develop.

      community New article on PP405..........

      in Research/Science  109 upvotes 1 year ago
      Scientists at UCLA have developed a promising treatment for male pattern baldness using a molecule called PP405, which can potentially stimulate dormant hair follicles. Initial trials showed significant results within a week, but larger clinical trials are needed to confirm its efficacy and safety.

      community Something not talked about in the hair transplant industry

      in Transplants  111 upvotes 6 months ago
      Hair transplant success largely depends on individual biology, with many patients needing multiple procedures to achieve satisfactory density. Even top surgeons can't guarantee results, and many people use additional treatments like Minoxidil and Finasteride.

      community 3 hair transplants + finasteride + minoxidil (full review)

      in Transplants  120 upvotes 1 year ago
      A user shared their experience with three hair transplants, finasteride, and minoxidil to combat severe hair loss, achieving significant regrowth. They discussed the process, costs, and maintenance, emphasizing that transplanted hair is permanent and doesn't require ongoing medication.

      community Mechanism of action of alfatradiol (17 alpha estradiol)

      in Research/Science  6 upvotes 1 year ago
      The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.