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community Oral Minoxidil - The Hyper-Responder Concept

in Research/Science 4 upvotes 5 months ago

Minoxidil's effectiveness varies due to genetic differences in the SULT1A1 enzyme, affecting how well it converts to its active form, minoxidil sulfate. Hyper-responders may experience rapid hair growth and increased side effects, such as pericardial effusion, even at low doses.

community Unused Eucapil- anyone want it?

in Product 1 upvotes 1 year ago

The conversation is about a user offering free unused Eucapil after switching to finasteride for hair loss treatment. The user did not use Eucapil and is willing to give it away locally or ship it if costs are covered.

community My first 5 week journey so far. Am I a hyper responder?

in Progress Pictures 1 upvotes 1 year ago

The user reports noticeable hair growth after 5 weeks using finasteride, minoxidil, dermarolling, and ketoconazole. They seek confirmation of their progress and question if they are a hyper responder.

community Six month update: .5mg Dut, Min 5% foam, Olly hair gummies (all once daily)

in Progress Pictures 275 upvotes 2 months ago

The user experienced significant hair regrowth and increased density after six months of using 0.5mg Dutasteride, 5% Minoxidil foam, and Olly hair gummies daily. The user plans to discontinue the gummies, believing the medications are primarily responsible for the improvement.

community How analogous are pumpkin seeds to fin/dut?

in Finasteride/Dutasteride 4 months ago

Eating pumpkin seeds is unlikely to cause significant hormonal changes or side effects like decreased libido or erectile dysfunction. Pumpkin seeds are not an effective substitute for finasteride or dutasteride in treating hair loss.

community 8 months on dut and just keep shedding

in Finasteride/Dutasteride 4 upvotes 4 months ago

The user experienced increased shedding and side effects like oily skin and acne after switching from finasteride to dutasteride, despite initially having success with finasteride. They also tried oral spironolactone, which reduced libido but didn't help with hair loss, and are considering returning to finasteride only.

community Pelage PP405 Phase 2a completed.

in Research/Science 61 upvotes 2 months ago

Minoxidil, finasteride, and RU58841 are discussed as treatments for hair loss, with excitement around a new drug, PP405, and a reformulated oral minoxidil in trials. Concerns about cost, side effects, and long-term use are also mentioned.

community Isn't it kind of strange that hair loss happens at where the 2 main superficial temporal arterty branches (temples and crown) are?

in Chat 5 upvotes 2 years ago

Hair loss may be linked to blood flow and inflammation, with treatments like Minoxidil, finasteride, and quercetin being discussed. The conversation also mentions the role of 5AR enzyme distribution in hair follicles.

community Discussion: High DHT levels while on Fin+Dut with substantial progress (pics)

in Progress Pictures 63 upvotes 3 years ago

A user's experience with using 5AR inhibitors (Finasteride and Dutasteride) in combination with Minoxidil foam and microneedling, which resulted in substantial improvements to their crown density and hairline, despite high systemic levels of testosterone and dihydrotestosterone.

community It's so over. Im beyond cooked

in Update 5 months ago

The user is experiencing hair loss despite using Dutasteride and plans to try RU58841, considering adding Oral Minoxidil. They express frustration with diffuse thinning and seek advice on managing hair loss.

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