PP405, a topical LDH inhibitor, has shown to stimulate hair follicle stem cell proliferation in humans with moderate hair loss. They are advancing to more detailed trials this year.
Hmi115, a prolactin receptor blocker, showed promise for hair growth, but results from Phase 2 trials have not been published. ABS-201, an AI-based analog, is expected to begin trials in December 2025, while commercialization of treatments like PP-405 is anticipated around 2027.
The user had a hair transplant in December 2024 and started using topical minoxidil and finasteride in March 2025, along with dermarolling and multivitamins. They are experiencing increased hair shedding and are questioning if it's the "dread shed" phase.
The user has been using oral finasteride and minoxidil for five months with some progress and plans to switch to dutasteride, while also considering a hair transplant for better coverage. Suggestions include adding microneedling, Nizoral shampoo, and possibly using both oral and topical treatments for improved results.
Kintor Pharma has started a Phase II trial in China for GT20029, a potential new treatment for hair loss. Participants are discussing the significance, potential release dates, and comparing it to other treatments and technologies like stem cell hair transplants and SAMIRNA.
The conversation jokes about using hair loss treatments like finasteride, minoxidil, and derma rolling on a baby, with suggestions ranging from starting treatment immediately to accepting baldness and focusing on other aspects of life. Some users suggest extreme measures like hair transplants in Turkey.
A 22-year-old male experiencing diffuse thinning started finasteride and 2% minoxidil 8 months ago, then switched to 5% minoxidil with tretinoin 4 months ago. Despite initial improvement in hair density, he is now experiencing increased hair shedding, losing 100-200 hairs daily.
The user "baselinesims" shared their progress in treating hair loss using 1mg oral finasteride, 1ml topical minoxidil, 0.5ml topical dutasteride, keto shampoo, cosmerna, and micro needling. They are happy with the progress so far, with diffuse thinning being taken care of and baby hairs showing up. They plan on getting a hair transplant in the future. Other users commented on the improved appearance and mentioned that the lighting in the photos may affect the comparison.
The conversation discusses hair transplant experiences and decisions, focusing on whether individuals would choose the same doctor again. Treatments mentioned include Minoxidil, finasteride, and RU58841.
The user is experiencing hair regrowth using finasteride, minoxidil, and KX-826. They regret not starting treatment earlier but are now seeing progress.