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      community How good are anti-androgens? Are they worth seeking?

      in Research/Science 2 weeks ago
      The conversation discusses hair loss treatments, including dutasteride, oral minoxidil, finasteride, and potential additions like topical finasteride, minoxidil, micro-needling, and topical anti-androgens such as RU58841. The effectiveness and worth of these treatments, including localized dutasteride mesotherapy, are considered.

      community Switching from oral to topical dut

      in Finasteride/Dutasteride  1 upvotes 2 months ago
      Switching from oral to topical dutasteride can cause shedding due to changes in DHT levels, and it's recommended to overlap both treatments to minimize this effect. Topical dutasteride may cause scalp irritation, and the user is considering dutasteride mesotherapy as an alternative.

      community 22 year old, losing hair for 1 year

      in General  192 upvotes 10 months ago
      A 22-year-old male experiencing hair loss suspects androgenetic alopecia (AGA) and possibly telogen effluvium (TE), with a noted improvement in scalp itch after adopting a gluten-free diet. He is advised to consider treatments like finasteride or minoxidil and to check iron and ferritin levels.

      community What happened to topical dutasteride??

      in Finasteride/Dutasteride  28 upvotes 1 year ago
      Topical dutasteride is considered for hair loss, but concerns about systemic absorption and side effects like reduced libido are common. Users have mixed results, with some preferring oral finasteride or dutasteride despite side effects, while others find topical treatments beneficial but challenging.

      community Feel like im not making process. Had insane shed. (Min/Fin/HRT)

      in Progress Pictures  1 upvotes 1 day ago
      The user started using oral minoxidil and estradiol in August 2025, added finasteride in December, and experienced significant hair shedding in February/March. They switched to estradiol injections and are considering their hair washing routine, while another user suggested consulting a dermatologist and possibly trying dutasteride.

      community Stumbled on some research

      in Research/Science  6 upvotes 5 years ago
      Elevated PGD2 levels in bald scalp tissue may contribute to hair loss, and treatments like castor oil, finasteride, and minoxidil are discussed as potential solutions. Some users explore alternatives like oral castor oil and cetirizine for those who cannot use finasteride.

      community Mental Health and Finasteride Questions

      in General  162 upvotes 1 year ago
      A 20-year-old with anxiety and depression is considering finasteride for hair loss but is worried about potential side effects. They decide to consult a doctor and consider starting with a low dose, while also exploring topical finasteride as a potentially safer option.

      community Has anyone had a hair transplant while on pyrilutamide?

      in Treatment  4 upvotes 1 year ago
      The user is considering starting pyrilutamide before a scheduled hair transplant, having previously used oral minoxidil and finasteride with worsening results. They also tried dutasteride, which worsened their hair and made their skin oily.

      community Terrible scalp itch and hair loss

      in Satire  16 upvotes 3 years ago
      Severe scalp itching and hair loss, possibly linked to seborrheic dermatitis, are discussed, with treatments like Dutasteride, Finasteride, and various shampoos mentioned. Some users find relief from itching with DHT blockers like Finasteride, while others suggest consulting multiple dermatologists for accurate diagnosis.

      community Temporalis Hypertrophy and hair loss

      in Treatment  24 upvotes 10 months ago
      Hair loss treatments include finasteride, minoxidil, and scalp exercises. Opinions vary on the effectiveness, with some attributing hair loss to muscle tension and inflammation, while others focus on genetics and DHT.

      community 10 day solo pyrilutamide update

      in Chat  11 upvotes 3 years ago
      The user started using pyrilutamide for hair loss on January 24, applying 1ml daily without other treatments, and after 10 days noticed reduced hair shedding and improved hair quality, with plans to continue for at least 6 months. They experienced chest pain initially, which could be related to starting methylphenidate or pyrilutamide, but the pain has since subsided.
      Any experiences with fin/dut alternatives?

      community Any experiences with fin/dut alternatives?

      in General  76 upvotes 10 months ago
      The user is exploring alternatives to finasteride and dutasteride due to concerns about side effects, and is using rosemary and jojoba oil, ketoconazole, minoxidil, microneedling, multi-peptide serum, saw palmetto, and stinging nettle for hair loss. They are also considering CB 03 01 and spironolactone.

      community Are there actual risks with oral minoxidil? How can they be mitigated

      in Minoxidil  20 upvotes 4 weeks ago
      Oral minoxidil can cause side effects like heart issues, increased body hair, and facial puffiness, but these are often dose-dependent and temporary. Users report varying experiences, with some combining it with finasteride or RU58841 for better results, while others experience minimal or no side effects.

      community Nest topical compound stack to fight hair loss

      in Treatment  1 upvotes 2 years ago
      The user is seeking advice for the best topical treatment to combat their ongoing hair loss, despite already using oral dutasteride, RU-58841, and minoxidil. They are considering adding CB-03-01 or topical Spiro to their regimen to lower testosterone levels at the follicles.

      community I always hear the advice to reduce scalp inflammation. What are some non-steroidal ways to reduce inflammation?

      in Treatment  13 upvotes 9 months ago
      Non-steroidal ways to reduce scalp inflammation include using topical melatonin, urea shampoo, Zyrtec, turmeric with black pepper, omega-3 supplements, a self-made topical solution with cetirizine, melatonin, and piroctone olamine, ketoconazole shampoo, witch hazel shampoo, tacrolimus, and lifestyle changes like a healthy diet and regular exercise. Some users also mentioned unconventional methods like infrared light therapy and a carnivore diet.

      community losing ground after a year with dut 0.5mg

      in Finasteride/Dutasteride  8 upvotes 7 months ago
      A 22-year-old has been using dutasteride (0.5 mg daily) for over a year but is experiencing increased hair shedding, scalp inflammation, and burning, and cannot use minoxidil due to side effects. Suggestions include consulting a dermatologist, trying oral minoxidil, microneedling, rosemary oil, caffeine shampoo, and considering other treatments like PRP or red light therapy.

      community fluridil (topilutamide) vs. cb-03-01 (clascoterone)

      in Research/Science  5 upvotes 2 years ago
      The conversation is about comparing the effectiveness of fluridil and clascoterone in preventing hair loss and inquiring about their use as standalone treatments. There is a question about the concentration of the fluridil brand for efficacy.

      community Can this fate be avoided? Or must i simply accept it.

      12 years ago
      A 19-year-old is experiencing early hair loss, possibly due to oily skin, stress, poor diet, and lack of sleep. They have tried ketoconazole shampoo without success and plan to visit a dermatologist for further advice.

      community Losing the gains and frontline of battle

      in Progress Pictures  59 upvotes 1 year ago
      The conversation discusses hair loss treatments, specifically the use of dutasteride, finasteride, and other methods like PRP, laser, and mesotherapy. Despite these treatments, the user is experiencing hair loss, and others suggest consulting a dermatologist, considering alternative treatments, and addressing potential scalp inflammation.

      community I’m an outlier, very sensitive to Saw Palmetto/Fin

      in Treatment  4 upvotes 4 years ago
      The user experienced sensitivity and side effects from finasteride and Saw Palmetto, leading to swollen and sensitive breasts, and decided to stop finasteride after two weeks. They are now trying Saw Palmetto, Biotin, and Ashwagandha, while others in the conversation discuss their own experiences with hair loss treatments like minoxidil and finasteride.

      community Does creatine increase DHT/cause hair loss?

      in Research/Science  20 upvotes 3 years ago
      Creatine is reported to cause increased hair shedding, but there is no scientific evidence linking it to hair loss. Some users manage hair loss with finasteride and minoxidil or consider stopping creatine if shedding worsens.