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      community DHT blockers for women, and your experiences with them?

      in Female  5 upvotes 5 years ago
      A user shared their experience with Spironolactone for hair loss, noting it stopped hair loss and cleared acne but had side effects like frequent urination and potential kidney damage. They also mentioned Bicalutamide as a potentially more potent DHT blocker with fewer side effects and asked for others' experiences with DHT blockers for women.

      community Clascoterone/ Breezula will it work

      in Research/Science 5 days ago
      Breezula's effectiveness is uncertain, with some users skeptical about its potential and others noting its recent availability on the grey market. A user reported success with a stack of Dutasteride (oral), Minoxidil (topical), and RU58841 (topical), achieving significant hair improvement after 18 months.

      community Pyrludimide (KX-826) or Breezula (clascoterone)

      in Treatment  9 upvotes 3 weeks ago
      The conversation is about hair loss treatments, specifically Pyrludimide (KX-826) and Breezula (clascoterone), with the user unable to tolerate finasteride and dutasteride. The user plans to use these treatments alongside minoxidil, considering the efficacy and availability of each option.

      community Are any of you using topical spironolactone ?

      in Treatment  4 upvotes 8 months ago
      The user is using topical dutasteride, minoxidil, and spironolactone for hair loss, with positive results after adding spironolactone. Another user takes oral spironolactone, dutasteride, and finasteride, noting decreased libido but no major side effects.

      community What is everyone's stack and why?

      in Treatment  21 upvotes 1 year ago
      People are using various treatments for hair loss, including dutasteride, finasteride, minoxidil (both oral and topical), RU58841, and ketoconazole shampoo. Some also use additional methods like microneedling, vitamins, and oils, with mixed results and personal preferences influencing their choices.

      community Alfatradiol only for mild thinning

      in Product  1 upvotes 5 months ago
      Alfatradiol is considered safe but less effective than finasteride for hair loss. One user reported subtle regrowth using alfatradiol with finasteride and minoxidil, while another found alfatradiol ineffective.

      community Research behind RU-58642? Has anyone heard of this?

      in Research/Science  1 upvotes 10 months ago
      RU-58642 is a powerful anti-androgen that was not developed further, possibly due to safety concerns or financial reasons. RU58841 is a topical alternative, but it is less effective than finasteride and dutasteride, and its long-term effects are not well-studied.

      community The sTressful Journey - 4 Year Battle

      in Update  8 upvotes 2 years ago
      The user experienced no results for 3.5 years while using finasteride, minoxidil, and microneedling, but saw improvement after increasing Dutasteride to 0.6mg daily. Current routine includes Dutasteride 0.6mg, minoxidil once a day, and supplements like collagen, biotin, and vitamin D.

      community Losing ground on 3x a week finasteride

      in Finasteride/Dutasteride  3 upvotes 3 months ago
      The user is experiencing hair loss despite using finasteride three times a week due to side effects and is considering alternatives like topical finasteride, estrogen blockers, or dutasteride. They are also interested in potential treatments like GT20029 and pyrilutamide.

      community Dutasteride 2.5 mg Progress (6 months)

      in Progress Pictures  151 upvotes 6 days ago
      A 49-year-old male switched from Finasteride to Dutasteride 2.5 mg daily, along with oral Minoxidil 5 mg, resulting in significant hair regrowth and stopping hair loss after six months. Despite initial side effects like adrenaline spikes and urinary issues, the user is satisfied with the results and plans to continue the treatment.

      community Duoxidil / Dutasteride/ Minoxidil

      in Minoxidil  83 upvotes 1 year ago
      The conversation discusses a user's positive experience with hair loss treatments, including Duoxidil, oral Dutasteride, oral Minoxidil, and biotin, noting no side effects and effective results. The user plans to start a new cycle of Dutasteride and PRP sessions.

      community Topical minoxidil and salicylic acid

      in Minoxidil  4 upvotes 1 year ago
      The user has been using finasteride for 6 months with decent results and recently added topical minoxidil. They are concerned that salicylic acid in their skincare products might reduce minoxidil's effectiveness.

      community My treatment from 2023 to 2025

      in General  83 upvotes 1 year ago
      The user experienced initial success with finasteride and topical minoxidil, but hair loss returned, leading to changes in treatment including dutasteride, oral minoxidil, and supplements. Despite increasing minoxidil dosage, hair loss persisted, prompting consideration of injectable treatments.

      community If dutesteride and oral minoxidil doesn’t work that’s it right?

      in Treatment  20 upvotes 1 year ago
      A user is experiencing continued hair loss despite using 0.5mg dutasteride and 2.5mg minoxidil, and is seeking advice on why the treatments aren't working and how to address potential androgen receptor sensitivity. Replies suggest getting tested and considering scalp micropigmentation (SMP).

      community Proposed Alternative stack to fin/min combination

      in Treatment 10 months ago
      A user proposed an alternative hair loss treatment stack using topical caffeine, copper, microneedling, and red light as a natural option for those experiencing side effects from finasteride or minoxidil. Other users expressed skepticism, emphasizing that finasteride and minoxidil remain the most effective treatments, while the proposed alternatives are unlikely to provide long-term results.

      community The solution for Topical Fin non responders?

      in Finasteride/Dutasteride  1 upvotes 2 months ago
      The user is considering using tretinoin with topical finasteride due to poor absorption and side effects from oral finasteride. They are also contemplating switching to topical dutasteride, while others suggest trying oral minoxidil or lower oral doses.

      community Rate my stack! (Using a nuclear protocol)

      in Finasteride/Dutasteride  17 upvotes 5 years ago
      A hair loss regimen involving Dutasteride, Oral Minoxidil, Mesotherapy, Topical Minoxidil/Finasteride, RU58841, Alfatridiol, Microneedling, LLLT, Keto shampoo, Vitamin K/D/Fish oil/Borage Oil/MSM, Oral Castor oil and Niacin. It also mentions products that have been dropped from the regimen due to not being worth the hassle or messing with libido.

      community God bless this sub and medications!

      in Progress Pictures  732 upvotes 6 months ago
      The user achieved significant hair regrowth using 0.5mg oral Dutasteride, 2.5mg oral Minoxidil, topical Minoxidil twice daily, Ketoconazole shampoo twice a week, and weekly dermastamping with no side effects. Results were noticeable after 2-3 months, with the best results at 9 months.

      community What is the consensus on RU58841 powder vs topical?

      in Treatment  1 upvotes 1 year ago
      The user is considering using RU58841 and pyrilutamide for hair loss, debating between powder and topical forms, and is currently using a combination of dutasteride, finasteride, minoxidil, tretinoin, and supplements. They report no significant side effects from finasteride and dutasteride, and are seeing some hair growth, but not on the scalp.