KX-826/pyrilutamide is undergoing an additional one-year safety and efficacy trial in China after a six-month study. Some participants speculate on the reasons for the extended trial and discuss the potential of other treatments.
The user has been using topical finasteride for seven months and minoxidil for three years, with added tretinoin gel for ten months, and is experiencing continuous shedding without signs of regrowth. They are questioning if the amount of shedding is normal at this stage of treatment and if there's a correlation between finasteride response and the rate of hair loss.
User considers trying RU58841 for hair loss and asks for advice on its effectiveness and application. Responses vary, with some reporting positive results and others warning about potential risks or lack of change.
Oral minoxidil users should monitor heart health with periodic echocardiograms and cardiologist visits due to potential side effects. While some experience serious side effects, they are rare, and the benefits for hair growth often outweigh the risks.
RU58841 and pyrilutamide are being discussed as potential hair loss treatments, with some users reporting side effects. There is interest in these treatments as alternatives to 5ar inhibitors and oral minoxidil due to concerns about safety and side effects.
A user experienced severe side effects, including erectile dysfunction and testicular pain, after taking finasteride for hair loss. They recommend sticking to minoxidil and biotin and avoiding finasteride due to potential risks.
Veradermics' new hair loss treatment, VDPHL01, is likely a modified release oral minoxidil, which has received $75 million in funding for clinical trials. Despite skepticism about investing in a known treatment, some believe it could offer improved efficacy and reduced side effects.
An update on the use of Pyrilutamide, a new drug for hair loss, which has resulted in no shedding or testicle ache; other users have questioned the science behind this and shared their own experiences with Finasteride, Minoxidil, and microneedling.
The user experienced negative side effects from saw palmetto, including low libido and energy, and found some improvement after using Maca and Acetyl L-Carnitine. They emphasize lifestyle changes and positivity for recovery, while expressing caution about saw palmetto's side effects.
OP believes RU58841 affected their thyroid, causing hypothyroidism and impacting minoxidil's effectiveness. They plan to start thyroid medication to improve hair regrowth.
A 22-year-old experiencing worsening hair loss after initially stabilizing on Dutasteride, despite adjusting the dosage. They cannot use Finasteride or Minoxidil due to side effects and are seeking advice and planning to consult a specialist.
A medical student experienced hair loss slowing with Finasteride but developed severe, treatment-resistant insomnia. They tried various medications with little effect, suspecting Post-Finasteride Syndrome, and others suggested the insomnia might be linked to Finasteride's impact on neurosteroids.
Belgium disagrees with the EMA and does not authorize the 1 mg oral form of finasteride for androgenic alopecia, citing a negative benefit-risk ratio. Despite this, some individuals in Belgium can still obtain finasteride through prescriptions, and there is debate over its mental health risks versus its benefits for hair loss and other health issues.
In Austria, finasteride prescriptions are restricted due to suicide risk concerns, with new prescriptions only for current users. Alternatives like topical finasteride, dutasteride, and online purchases face legal challenges.
A user started taking oral minoxidil using Rogaine, despite concerns from others about its safety and proper use. They plan to update on their progress.
The user experienced significant hair regrowth using finasteride and minoxidil but developed erectile dysfunction. They are considering stopping finasteride and relying on minoxidil alone to see if the side effects improve.
The conversation is about someone who initially had positive results with Minoxidil for hair loss, lost those gains due to a hospital stay, and is now not seeing the same results upon resuming treatment. They plan to add microneedling and/or tretinoin to their regimen and are seeking success stories from others who did not respond to Minoxidil alone.
The user started finasteride again, using it every other day, along with a laser helmet, inversion massage, and various supplements. They are considering Minoxidil but had a bad reaction previously and plan to get hair grafts.
People are sharing their experiences with different dosages of dutasteride and finasteride for hair loss. Many report shedding initially but some see improvements over time, with some also using minoxidil.
User shared before and after photos of hair regrowth using Dutasteride 5x a week for 19 months. They experienced significant improvement and thanked others for their support.
Most users did not visit a dermatologist before starting finasteride, opting to purchase it directly or through a primary care physician. Some users shared experiences of side effects and emphasized the potential benefits of medical advice and monitoring.
Switching from finasteride to dutasteride improved erections, sex drive, and mood for one user, though experiences vary widely. Some users report fewer side effects with dutasteride, while others experience more severe issues or hair loss.
Finasteride is generally seen as more successful for hair loss than Dutasteride, with fewer negative experiences reported. Dutasteride is considered more effective but often leads to more complaints, possibly due to higher expectations or improper use.
Switching from daily 0.5mg dutasteride to three times a week may reduce side effects without worsening hair loss. Bloodwork showed no abnormalities, supporting the change.
The conversation is about disappointment with pyrilutamide's performance as a hair loss treatment, with some users expressing interest in other treatments like Verteporfin, GT20029, and RU58841, while others suggest sticking with established treatments like finasteride or dutasteride.